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Name : hpaE (TSC_c10440) Accession : YP_004202215.1 Strain : Thermus scotoductus SA-01 Genome accession: NC_014974 Putative virulence/resistance : Virulence Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.60 Position : 987993 - 989543 bp Length : 1551 bp Strand : + Note : - DNA sequence : ATGAGGTACCCGGACCAGGTGGCAGGGATTCCCTGGGAACGGATCGAGGCCATTCGAAACGCCCTAAAGGGGTGGACGGC CCTCCACTTCATCGGCGGGGAGTTCCGCCCCTCGGAAAGCGGGGAGGTCTTCCCCACCTTGGATCCTTCCACCAACGAGG TGCTCTCCCATGCGGCCCGGGGCGGGGAGAGAGAAGTGGACCGGGCGGCCAAGGCGGCCCACGAGGCCTTCCAGCGGTGG AGCCGCACCCCGGCCCGGGAGAGGAAGCGCTACCTCCTGAGGATCGCCGAGCTTTTGGAAAAGCATGCGGATGAGCTGGC GGTGGTGGAGGCCTTGGATGCCGGGCAGGTGCTGCGGATTGTCAAGGCCCAGGTGGCCCGCTCCGCGGAGAACTTCGCCT TCTACGCCGAGTACGCCGAGCACGCCATGGAGGACCGCACCTTCCCCGTGGACCGGGACTGGCTTTACTACAGCCTGAGG GTCCCGGCTGGGCCGGTGGGCATCATCACTCCCTGGAACGCTCCCCTGATGCTTTCCACCTGGCGCATCGCCCCGGCCCT GGCCTTCGGGGACACGGTGGTCCTGAAGCCCGCGGAGTGGAGCCCCTTAACCGCCAGCAAGCTGGCGGAGATCGTGCAGG AGGCGGACCTTCCCCCTGGGGTCTTCAACCTGGTCCAGGGCTACGGCGAGGAGGCGGGGGCTGCCCTGGTGGCCCATCCC CTCGTTCCCCTCATCACCCTCACCGGGGAGACGGAAACCGGGAAGATCGTCATGCAAAACGCCGCCCGCCACCTTAAGCG GCTCTCCCTGGAGCTTGGCGGGAAAAGCCCGGCCTTGGTCTTTGCTGACGCCGATTTGGAAAGGGCTTTGGACGCGGTGC TCTTCCAGATCTACTCCTTCAACGGGGAGCGGTGCACAGCGAGCTCCCGCCTCCTGGTGGAGGAGTCCATCTTTGAAACC TTTGTGGAGAGGGTGGCGGAACGGGCGCGGGCCATCCGGGTGGGCCATCCCCTGGACCCCGAGACCGAGGTGGGCCCCCT CATCCACCCCGAGCACCTGGAGAGGGTTTTGGGGTATGTGGAGGCGGGCCTTAAGGAGGGGGCAAGGCTTCTCGTGGGCG GGAAGAGGGCCACCACCTCCTTCCGCGGGGAGGATCTTTCCCAGGGGAACTACCTGGAGCCCACCCTCTTCGTGGGGGAA AACCACATGAAAATCGCCCAGGAGGAGATCTTCGGGCCCGTCTTGGTGGCCATTCCTTTCAAGGACGAGGAGGAAGCCCT TAGGAAGGCCAACGACACCCGGTATGGCCTTGCGGCCTACGTGTTCACCCGGGACTTGGAAAGGGCCCATCGCCTGGCCC TGGAGCTAGAGGCGGGCCTCGTTTACCTGAACAGCCACAACGTGCGCCACCTGCCCACCCCCTTTGGCGGGGTGAAGGCC AGCGGGGAGCGGCGGGAGGGTGGCCTTTATGCTCTTGAGTTTTACACCGACCTCAAGGCCGTGGGGCTTCCCCTGAGGCC CCCCCACGTGCCCAAGTTCGGAAAGAGGTGA Protein sequence : MRYPDQVAGIPWERIEAIRNALKGWTALHFIGGEFRPSESGEVFPTLDPSTNEVLSHAARGGEREVDRAAKAAHEAFQRW SRTPARERKRYLLRIAELLEKHADELAVVEALDAGQVLRIVKAQVARSAENFAFYAEYAEHAMEDRTFPVDRDWLYYSLR VPAGPVGIITPWNAPLMLSTWRIAPALAFGDTVVLKPAEWSPLTASKLAEIVQEADLPPGVFNLVQGYGEEAGAALVAHP LVPLITLTGETETGKIVMQNAARHLKRLSLELGGKSPALVFADADLERALDAVLFQIYSFNGERCTASSRLLVEESIFET FVERVAERARAIRVGHPLDPETEVGPLIHPEHLERVLGYVEAGLKEGARLLVGGKRATTSFRGEDLSQGNYLEPTLFVGE NHMKIAQEEIFGPVLVAIPFKDEEEALRKANDTRYGLAAYVFTRDLERAHRLALELEAGLVYLNSHNVRHLPTPFGGVKA SGERREGGLYALEFYTDLKAVGLPLRPPHVPKFGKR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 8e-93 | 48 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 1e-67 | 44 |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-63 | 42 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-65 | 41 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-65 | 41 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-65 | 41 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 6e-65 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| hpaE | YP_004202215.1 | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase | VFG0082 | Protein | 9e-64 | 42 |
