Gene Information

Name : GM18_4265 (GM18_4265)
Accession : YP_004200955.1
Strain : Geobacter sp. M18
Genome accession: NC_014973
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 5007685 - 5009010 bp
Length : 1326 bp
Strand : -
Note : TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; KEGG: gbm:Gbem_3835 flagellar protein export ATPase FliI; SMART: AAA ATPase

DNA sequence :
GTGGGGATTGATCTCGCCCGCTACATGCCGGTGGTCGAAGCCGCCAAGCCGGTCCGTTTCCACGGCAAGGTGACCCAGGT
GGTCGGCCTGGTCATCGAGGGGTTCTGCCCCGAGACGGCGGTGGGGAGCGTCTGCGAGGTGCACTCCGAGGGGCATGCCC
CGATCCCCGCCGAGGTGGTCGGCTTCCGTGACAACAAGACGCTCTTGATGCCGCTGGGCGAGCTGCGCGGCGTCGGGCTG
GGAAGCGTGATCTCGGTGCGGCGCGAGAAGGCGGCCCTGGGGGTCGGCCCGGCCCTGCTGGGAAGGGTCATAGACGGGCT
GGGGGAGCCGATCGACGACAAGGGGCCCATCGAGGTGGTGGACGAATACCCGATCTACGCCCTGCCGGTGAACCCCATGA
AGAGGCGCCCGATCAGGAAGCCCCTGAACCTGGGCATCCGCGCCATCAACGGGCTTCTGACCTGCGGCGAGGGGCAGAGG
GTGGGGATCATGGCCGGCTCAGGCGTCGGCAAATCGACCCTTCTGGGCATGATCGCCCGCTATACCGAGGCCGACGTGAA
CGTGATCGCCCTGATCGGCGAGCGCGGCCGGGAACTCAGGGAATTCATCGAGAAGGACCTGCAGGCGGAGGGGCTCAGGA
AATCGGTCGTGGTGGTGGCGACCAGCGACCAGCCACCGCTGGTCAGGATGCGCGGCGCCTACATAGCGACCACCATCGCC
GAGTACTTCCAGGCCCAGGGGAAGAAGGTGCTCCTGATGATGGACTCGGCCACCCGCTTCGCCATGGCGATGCGCGAGGT
GGGGCTAGCCATCGGCGAGCCCCCCACCACCAAGGGGTACACCCCGAGCGTTTTCGCCGCGCTCCCGAGGCTCTTGGAGC
GGACCGGCAACTTCCAGGGGGGGAGCATCACCGGCCTGTACACCGTGCTGGTCGAGGGGGACGATTTCAACGAGCCGATC
TCAGACGCCATGCGCAGCATCCTGGACGGGCACATCATCCTGACCCGTGAGCTCGCGGCGCGCAACATCTACCCGCCGAT
CGACCTCTTGAACAGCGCGAGCCGCGTCATGAGCGACGTGACCAGCAGGGAGCACCGGGCGCTCGCCGGCCAGTTCAAGG
AGACGCTGGCCACCTATCGGCAGGCGGAGGACATGATCAACATCGGCGCCTACAAGGCCGGCAGCAACGCGAAGATCGAC
ATGGCGATCGCCAAGATGGAGCAGATGATCGCGTATTTGAAGCAGGACGTGGCGGACGAGGAGAATTTTGAGGAGTCCAT
AGCGGCCCTCTCCAGGATATTCGGGGTAGGAAGCCTCACGGAATAG

Protein sequence :
MGIDLARYMPVVEAAKPVRFHGKVTQVVGLVIEGFCPETAVGSVCEVHSEGHAPIPAEVVGFRDNKTLLMPLGELRGVGL
GSVISVRREKAALGVGPALLGRVIDGLGEPIDDKGPIEVVDEYPIYALPVNPMKRRPIRKPLNLGIRAINGLLTCGEGQR
VGIMAGSGVGKSTLLGMIARYTEADVNVIALIGERGRELREFIEKDLQAEGLRKSVVVVATSDQPPLVRMRGAYIATTIA
EYFQAQGKKVLLMMDSATRFAMAMREVGLAIGEPPTTKGYTPSVFAALPRLLERTGNFQGGSITGLYTVLVEGDDFNEPI
SDAMRSILDGHIILTRELAARNIYPPIDLLNSASRVMSDVTSREHRALAGQFKETLATYRQAEDMINIGAYKAGSNAKID
MAIAKMEQMIAYLKQDVADEENFEESIAALSRIFGVGSLTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-93 52
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-93 52
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-105 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-94 51
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-93 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-93 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-94 51
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-93 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 9e-94 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-94 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-85 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-85 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-84 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 6e-85 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-84 48
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-86 47
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-86 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-84 46
escN AAC38383.1 EscN Virulence LEE Protein 4e-85 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-84 46
escN AAK26715.1 EscN Virulence LEE Protein 2e-84 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-84 46
escN AAL57542.1 EscN Virulence LEE Protein 2e-84 46
escN AAC31513.1 L0034 Virulence LEE Protein 1e-84 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-84 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-84 46
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-84 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-72 46
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-82 46
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-84 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-84 45
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 5e-82 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-70 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-74 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-74 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-74 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-77 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-68 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-68 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-72 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-77 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 6e-78 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-81 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-77 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-72 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG2144 Protein 7e-106 53
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG0390 Protein 2e-106 52
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG0192 Protein 2e-109 51
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG0048 Protein 4e-106 51
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG1254 Protein 7e-96 49
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG2499 Protein 4e-89 49
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG0515 Protein 3e-85 48
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG2331 Protein 8e-87 46
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG0812 Protein 8e-85 46
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG0730 Protein 2e-85 46
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG1008 Protein 5e-73 44
GM18_4265 YP_004200955.1 FliI/YscN family ATPase VFG1778 Protein 2e-69 42