Gene Information

Name : GM18_3258 (GM18_3258)
Accession : YP_004199971.1
Strain : Geobacter sp. M18
Genome accession: NC_014973
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3830235 - 3831674 bp
Length : 1440 bp
Strand : -
Note : TIGRFAM: pyruvate kinase; KEGG: gem:GM21_3093 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
ATGTTCCGTCGCACCAAGATCGTAGCCACCGTCGGACCAGCCTGTGACTCCGAGGAGAAGCTGGACGCCCTGATCCACGC
CGGGGTCGATGTCTTCCGGCTCAACTTCTCCCATGGCGATTACGCCTCCAAGGCCGCGGTCATCAAAAGCGTCAGGAAGC
TCTCCCTGGAGCACGAACATGCGGTCGCCATTCTGGGTGACCTGCAGGGGCCCAAGATCCGCACCGGCCTCATGGAAGGG
GGCTCCATGCAGCTCGTGGCCGGGAGCGAGGTGGTGGTTACCACGAGGCAGGTGCTGGGGCAGGGAAGCCTGATCCCGAC
CATCTATCAGGGGCTGCCCCGCGACGTGAAGCCGGACGACCGTATCCTTCTGGACGACGGCCTGATGGAACTCAAGGTGC
TCGGGGTGGAGGGGGACGAGGTGCGCTGCCAGGTGGTGACCGGCGGACTGCTCAAGGACCGCAAGGGGATCAACCTACCC
GGCGCCAAGGTTTCCGCTCCCGCGCTCACCGAAAAGGACCGCGAGGACCTGCAGTTCTGCATGGACCAGCAGATGGACTA
TGTGGCCCTCTCCTTCGTGCGCGAGGCCTCCGACGTGGCCGAGTTGAAGGAGATCATCGAAAAGGCGGGTTCGCATCTGC
GCATCATCGCGAAGATCGAGAAGCCCGAGGCGGTTCTTAACTTCGCGGCCATCCTCCGTGTCTCCGACGGGATCATGGTG
GCGCGCGGCGACCTGGGGGTGGAATTGAGCCCGGAGAAGGTGCCGCTGATCCAAAAGCGCATCATCCGCAGCTGCAACGA
CGCCGGAAAGCCGGTGATCACGGCCACCCAGATGCTGGAAAGCATGGTGAACAACCCGCGCCCGACCCGCGCCGAAACCT
CCGACGTCGCCAACGCCATCCTGGACGGCACCGATGCCATCATGCTCTCCGCCGAGACCGCATCCGGCAAGTACCCGCTA
GAAGCCGTCTCCATGATGGTGCAGGTGGCGCGCGACGTGGAGGGGGACCCGCAGCTCATGGCGCAGTGCTGCAGGGGACC
CAGCGGGCAAAACGGTCTTCCCAACGTCTCCGAGGTGATCGGCATGGCCGCCTGCCGCGCGGCGGAGAGCGTCAAGGCCG
CGGCGATCCTCGCCTTCACCCAGACCGGCAGCACCGCGGCCCTTGTTTCCAAGTACCGCCCCGCGCAACCCATCATCGCC
GTGACGCCGTCGCAGGAGGTGCGTCGCGGGCTTGCCCTGTACTCGGGGGTCCATGCGCTTCGCGTCGACATCGAAGGTGA
CACCGAGTCTCAGATCCTGTCGGTCGAGGCGGCGGTTCTCGCCATGGGATGGCTCAAAAAGGGGGACCTTGTGGTGATTA
CCATGGGAAGCCCACTCTCCAGCCCCGGTACCACCAACCTGATGAAGGTGCACCGGCTGGAGGAGCCGGGATCGGCCTGA

Protein sequence :
MFRRTKIVATVGPACDSEEKLDALIHAGVDVFRLNFSHGDYASKAAVIKSVRKLSLEHEHAVAILGDLQGPKIRTGLMEG
GSMQLVAGSEVVVTTRQVLGQGSLIPTIYQGLPRDVKPDDRILLDDGLMELKVLGVEGDEVRCQVVTGGLLKDRKGINLP
GAKVSAPALTEKDREDLQFCMDQQMDYVALSFVREASDVAELKEIIEKAGSHLRIIAKIEKPEAVLNFAAILRVSDGIMV
ARGDLGVELSPEKVPLIQKRIIRSCNDAGKPVITATQMLESMVNNPRPTRAETSDVANAILDGTDAIMLSAETASGKYPL
EAVSMMVQVARDVEGDPQLMAQCCRGPSGQNGLPNVSEVIGMAACRAAESVKAAAILAFTQTGSTAALVSKYRPAQPIIA
VTPSQEVRRGLALYSGVHALRVDIEGDTESQILSVEAAVLAMGWLKKGDLVVITMGSPLSSPGTTNLMKVHRLEEPGSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-78 45
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-78 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-79 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-78 44
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 3e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GM18_3258 YP_004199971.1 pyruvate kinase VFG0479 Protein 5e-79 45