Gene Information

Name : Despr_3256 (Despr_3256)
Accession : YP_004196674.1
Strain : Desulfobulbus propionicus DSM 2032
Genome accession: NC_014972
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3741656 - 3743101 bp
Length : 1446 bp
Strand : -
Note : COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR001697; KEGG: sfu:Sfum_2959 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate

DNA sequence :
ATGTACAACACGCCCATTCTGCCCGCCTGTAAAACCAAACTGGTCTGCACCATCGGTCCGGCCTCGGATTCGCCGGAGAT
GCTGGAGAAAATGCTCGAGGCCGGGATGAATATTGCCCGGCTCAATTTCTCCCACGGCGATTTCCGGGTGCACGGCGAGG
TGATTCGCCGCATTCGCCAGGCAGCGGAGCGGGTCAGCCGGCCGGTGGCGATCATGGCCGATCTGCCCGGACCCAAGATC
CGCATCGGTACCCTGGCCGTGGAACCGGTCGAGCTGGTCATCGGCGACTGTTTCACCCTGACCACCGAAGAGGTGGCGGG
CAATCGATCGATGGTTTCGGTGACCCTCAAGGAACTGCCCCAGGCGGTGCGGCCCGGTGATGTGTTGTTCATCAATGACG
GCTTGATTCAGGTGCGGGTGGAAGAGGTCGAGGAGGAACGGGTCCATTGCCGCGTGCTGGTCGGCGGCAAGCTGCGCTCG
AAAAAGGGCCTCAACCTGCCGGGGATCGATCTGGGCATCTCCGCCTTCACCGAGCACGATCGGAATTGCATGCGTTTTGC
CCTGGAGAACGGGGTGGACGCCATCAGCCAGTCCTTTGTCAACGATGCCGCCGACATCCGCGCGGTGCGCGAGGCGGCGG
CCGCAATGGGTTACCAGCCCTTTGTCATTGCCAAGATCGAGCGCGCCTCGATCCTGGAGAAGATCGACCAGATCCTGGAC
GAGGCGGACGGCGTGATGGTGGCCCGGGGCGATCTCGGGGTGGAACTGCCGATCGAGGAGATCGCCATCATGCAGAAGCT
GATCACCTCCCGCGCCAACCTGTTCGGCAAGCCGGTCATCACCGCCACCCAGATGCTCGAATCCATGACCAACAACCGCA
GACCGACCCGGGCCGAGGCCACCGACGTGGCCAACGCCATTCTCGACGGCACCGACTGTGTGATGCTCTCCGAGGAGTCG
GCCATGGGCCGTTATCCACTGGAGGCGGTGCGCATGCTGATGCAGATCGCCGTGGCCACCGAACCGCACCGCACCCGCCA
CAGTTACCGCAAGATGCCCGAACACCCGGTGTATACCGAGATTCGGGAGGTGGATTACATCGCCTCCAGCGTCAATGCCA
TCGTCAGCCACAACGATACCGTGGCCGCCATCCTCGCGCCCACGGACAGCGGCCTCACCGCCCGGCGGTTGTCGCGCTAC
AAGCTGCCCACTTGGGTTCTGGCGGTGAGTGCCAACAAGAAGACCTGCCGGGAATTGCTCTTTTCCTACGGGGTCTTTCC
CCTCTACGAGATCAATCACCCGGCGGACTGGACCGATTTTGCCCGTGATTACGCCTTGAAATACAATCTCAAGGGAAGCT
GCATCATCCAGACTGAAGGGCCGTCACCCGAAAACCCGCACCGGAACCACAAGATGGAGATTATCGATCTCCGCGAGATC
CGTTGA

Protein sequence :
MYNTPILPACKTKLVCTIGPASDSPEMLEKMLEAGMNIARLNFSHGDFRVHGEVIRRIRQAAERVSRPVAIMADLPGPKI
RIGTLAVEPVELVIGDCFTLTTEEVAGNRSMVSVTLKELPQAVRPGDVLFINDGLIQVRVEEVEEERVHCRVLVGGKLRS
KKGLNLPGIDLGISAFTEHDRNCMRFALENGVDAISQSFVNDAADIRAVREAAAAMGYQPFVIAKIERASILEKIDQILD
EADGVMVARGDLGVELPIEEIAIMQKLITSRANLFGKPVITATQMLESMTNNRRPTRAEATDVANAILDGTDCVMLSEES
AMGRYPLEAVRMLMQIAVATEPHRTRHSYRKMPEHPVYTEIREVDYIASSVNAIVSHNDTVAAILAPTDSGLTARRLSRY
KLPTWVLAVSANKKTCRELLFSYGVFPLYEINHPADWTDFARDYALKYNLKGSCIIQTEGPSPENPHRNHKMEIIDLREI
R

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-63 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Despr_3256 YP_004196674.1 pyruvate kinase VFG0479 Protein 1e-63 42