Gene Information

Name : Despr_2575 (Despr_2575)
Accession : YP_004196002.1
Strain : Desulfobulbus propionicus DSM 2032
Genome accession: NC_014972
Putative virulence/resistance : Unknown
Product : hydroxymethylbilane synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2952218 - 2953177 bp
Length : 960 bp
Strand : +
Note : COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: dak:DaAHT2_0535 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; SPTR: Porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase, C-terminal

DNA sequence : 
ATGAGAACATTGCTGCGCATAGGGACGCGCGCCAGCCTGCTGGCCGTGACCCAATCGACCTGGGTCAAGACCCAGATTGA
ACAGGCCCATCCGGGAACCCGGGTGGAGTTGGTGAAAATCACCACCAAGGGGGATCGCATCCTCGACGTGCCGCTGGCCA
AGGTCGGCGGCAAGGGGTTGTTTGTCAAGGAGATCGAAGACGCCCTCCTGGCCGGTGAGGTCGACCTGGCGGTGCATTCG
ATGAAGGATGTGCCCACCGAACTGCCGGAGGGGTTGCACATCGGCGTCATTCCGGTGCGGGAAACGCCCTACGATGCCTT
TCTCTCCAAGACATGCACCACGCTTGCCGATCTGCCGCAGGGCGCCACCATCGGCACCTCCAGCCTGCGGCGCAAATCAC
AGCTGATGGCGCTGCGGCCAGACCTGGACATCGTTGATCTGCGCGGCAACATCGACACCCGGCTACGCAAGCTCGATGAG
GGCGTCTATGACGCCATCATTCTGGCCGGCGCCGGACTGCGGCGTCTGCACTTGGAACACCGGATCACGGCCCTGCTGGA
ACCCACGCAAATGCTGCCGGCCATCAGCCAAGGAGCGCTGGGCATTGAACTGCGCCAGGATGACACCGAACTGGCCGACG
GGCTGCGCTTCCTTCACCACGGAGAAACCGCCGTCGCCGTCGAGGCCGAACGCGCCTTTCTGCTGCGCCTGGAAGGCGGT
TGCCAAGTGCCCATCGCGGCCCACGCCACGCTCGACAGCGGTTCGGTCACCCTGACGGGCCTGATTGCCAGCGTCGATGG
CCGGCAAATCCTCAAGGAAGCAACTACCGGCCCAGCCGAGCAGGCAGCACGCCTCGGTGCGCAATTAGCGCAAACCTTGC
TTGATCGAGGCGGCAAAGCCATTCTCGATGCGGTCTATTGCAGCGCATCAACGTCCCCCCATTCACCCCTTTCTGCCTGA

Protein sequence : 
MRTLLRIGTRASLLAVTQSTWVKTQIEQAHPGTRVELVKITTKGDRILDVPLAKVGGKGLFVKEIEDALLAGEVDLAVHS
MKDVPTELPEGLHIGVIPVRETPYDAFLSKTCTTLADLPQGATIGTSSLRRKSQLMALRPDLDIVDLRGNIDTRLRKLDE
GVYDAIILAGAGLRRLHLEHRITALLEPTQMLPAISQGALGIELRQDDTELADGLRFLHHGETAVAVEAERAFLLRLEGG
CQVPIAAHATLDSGSVTLTGLIASVDGRQILKEATTGPAEQAARLGAQLAQTLLDRGGKAILDAVYCSASTSPHSPLSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-74 58
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-74 58