Gene Information

Name : Despr_2224 (Despr_2224)
Accession : YP_004195659.1
Strain : Desulfobulbus propionicus DSM 2032
Genome accession: NC_014972
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 2536805 - 2538184 bp
Length : 1380 bp
Strand : +
Note : COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR003593: IPR000194: IPR020003: IPR005714; KEGG: dps:DP2659 flagellum-specific ATP synthase (FliI); PFAM: H+transporting two-sector ATPase alpha/beta subunit central region;

DNA sequence :
ATGGCCAACGTATCCGATTTGCTCACCGCCTTTTCTCCCATCCGTGTCTACGGCCAGGTGCACCGTATCGTCGGCCTGGT
GGTCGAGGGCACCTGCGCCCGTTCCTCCATCGGTTCCCTCTGTGAACTGTTTCCGCTCCAGGACGGCGAGGTCATTCCCG
CCGAGATCGTCGGCTACAGCAATAACCGGGCCCTGTTGATGCCCTTGGGCGAGTTGCGCGGCCTGGGACCAGGCAGCCGC
ATTCGGGTCAAGAAGGAACAGGCCACCATCAGCGTCGGCGACGGCTTGCTCGGTCGGGTACTCGACGGCATGGCCCAGCC
GCTCGATCAAGGGCCGCCCCTGTACCTGCCCCACGAAAAGGCGCTCTATTCCTTGCCGCCGGGGCCAATGCAGCGTGACG
CCATCACCCAGCCACTCGATCTCGGCATCCGGGCGATCAACGGCCTGCTGACCTGCGGCATCGGCCAGCGCATGGGGATC
ATGGCCGGATCGGGGGTGGGCAAGAGCGTGCTGCTGGGTATGATGGCCAAGTACGCCAAGGCGGACATCAACGTCATCGC
CCTGATCGGCGAGCGCGGCCGCGAAGTCAAGGAATTCATCGAACGCGATCTGGGCAAGGAAAGTCTTGCCCATTCGGTGA
TTGTCGCCGTCACCTCGGATCAGTCGCCGCTGTTGCGCATGCGTGGCGCCTTCGTCGCCACCGCCATTGCCGAGTATTTT
TGTCAGCGGGGCAAGAACGTGCTGTTGATGATGGATTCGGTGACCCGCTTTGCCATGGCCATGCGCGAGATCGGCCTGTC
CATCGGCGAACCGCCCACTACCAAGGGCTACACGCCGAGCGTGTTCGCCACTCTGCCCAAGCTGCTGGAACGGGCCGGAA
ATTTCCAGCACCAGGGTTCGATCACCGGCCTGTACACGGTGCTGGTGGACGGCGACGACTTGACCGAACCGGTGGCCGAC
TCGGTTCGTTCCATCCTCGATGGCCACATCGTGCTCTCCCGCAGCATTGCCGCCAAGAATCATTACCCGGCCATCGACGT
GATGATGTCCACCAGCCGGGTCATGCGTGACATCACCACCTCCCGCCACCGGGAATTGGCCGGCAAGGCCCGCAGCGTCA
TGGCCATATACCGGGAATCCGAGGACCTGATCAACATCGGTGCCTATGCCACGGGCAGCAATAAGAAAATCGACTATGCC
ATCTCACGGATGGACGCCATCAATGCCTTCCTCACCCAAGGATTCGAGGAATCCTCAACCCTTGAGGAAACTATTGCCGC
CATGGGCGAGCTGGTCAGCGACCGCCAGGGAAACGACCGCAGGCGAGCGGGGCGCAAGGGATTTGATCGACGAAAAACCG
ATATGTCGGCCGACGAGTGA

Protein sequence :
MANVSDLLTAFSPIRVYGQVHRIVGLVVEGTCARSSIGSLCELFPLQDGEVIPAEIVGYSNNRALLMPLGELRGLGPGSR
IRVKKEQATISVGDGLLGRVLDGMAQPLDQGPPLYLPHEKALYSLPPGPMQRDAITQPLDLGIRAINGLLTCGIGQRMGI
MAGSGVGKSVLLGMMAKYAKADINVIALIGERGREVKEFIERDLGKESLAHSVIVAVTSDQSPLLRMRGAFVATAIAEYF
CQRGKNVLLMMDSVTRFAMAMREIGLSIGEPPTTKGYTPSVFATLPKLLERAGNFQHQGSITGLYTVLVDGDDLTEPVAD
SVRSILDGHIVLSRSIAAKNHYPAIDVMMSTSRVMRDITTSRHRELAGKARSVMAIYRESEDLINIGAYATGSNKKIDYA
ISRMDAINAFLTQGFEESSTLEETIAAMGELVSDRQGNDRRRAGRKGFDRRKTDMSADE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-93 52
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-84 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-84 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-84 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-84 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-84 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-84 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 49
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-83 49
escN AAL57542.1 EscN Virulence LEE Protein 6e-83 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-83 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-83 47
escN AAC31513.1 L0034 Virulence LEE Protein 3e-83 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-83 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-83 47
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-83 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 7e-83 47
escN AAC38383.1 EscN Virulence LEE Protein 7e-83 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-83 47
escN AAK26715.1 EscN Virulence LEE Protein 6e-83 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-83 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-73 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-73 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-73 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-73 47
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-73 47
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 5e-77 47
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-82 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-60 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-61 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-81 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-81 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-69 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-64 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-65 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 9e-66 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-62 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-62 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 8e-70 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-69 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-69 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-73 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 4e-95 53
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 2e-93 51
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 5e-91 50
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 1e-91 50
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 1e-88 49
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 3e-88 49
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 1e-81 48
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 2e-83 47
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 4e-83 47
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 1e-73 47
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 2e-66 41
Despr_2224 YP_004195659.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 3e-65 41