Gene Information

Name : VVMO6_04208 (VVMO6_04208)
Accession : YP_004191433.1
Strain :
Genome accession: NC_014966
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 1418094 - 1419722 bp
Length : 1629 bp
Strand : -
Note : -

DNA sequence : 
ATGGTCGTCGCGACAACCGAAACACCAAAGCAGATACTCGATGGCTTTGTGCGTAAACCTAGTGTTCAAAGTGAACAATA
TCAGGCTGCAAATTTGTGGCGCAATTCGCCGCTGTGGCAAATTCTTCATCAGGGAGTAGGGCGTCACCCGGATAGGATAG
CGGTGACCGATAACCACACTTCACTGAGCTATCTCGAGTTGGCCAATCGCGTGGATAGGATCGCCGCTGGGTTGCGAGAA
GAAGGGCTTGTGTGTGGTGACAGTGTTGTCTTGCAGTTAGCCAATACACTCGATTTTCTCGTCGTGTTTTTTGCTCTTCA
GCGCCTTGGTGTGGTTCCCGTACTGGCATTACCTGCGCACGGTTTGGTCGAAATTCGCCACTTTATGCAACTCTCTGGGG
CAAGAGTGTACATCGGCTCCAATCATGAAAAGGATGACAAAGCGTTGGCGATTGCCACTCAGTTGCAAGCGGAACTATCA
ATATCCATTCGCTGCTATATCAGCGGGCATTTTGGTCAGTTTTCGCCGTTGCCAGAGTGTGACGCTGGCGATTTTACACC
AGCGATGGTAGACCCAGAACACCCGGCACTTTTCCTCGTTTCTGGAGGCACGACAGGGCTACCCAAACTGATCCCCCGTA
CCCACAATGATTATCTGTTTAATGTTGAGCAATGTGCGAAAGCCAGTGAAATCAGTGCGCAGGATGTGTATTTGGCGGTG
TTGCCTGCGGCACACAATTTTACCTTGGGTTGTCCTGGGATCTTAGGGGTGTTGAATACTGGCGGAAAAGTGGTTTTGAC
CACCAACCCAAGCCCAGATTATTGTTTTGAACTTATTGAAAAACAGCGTATTACCGCAACGGCGTTGGTGCCTGCATTGG
CGCAGCTGTGGACGGAGGCAACTCAATGGGAGTCGACGGATCGTTCGAGTTTACGTTTGATGCAAGTCGGTGGTTCCAAA
CTTGCTTATAGCGATGCGCTGGAAATGCAACACGCCTTTCCAAACGCGTTGCAGCAAGTTTTTGGTATGGCGGAAGGTTT
GATTGCGTGTACCCGTTTGGGCGACGACAAAGAAATTATTGCAACAAGGCAAGGTCGTCCTGTCAGCGAATGGGACGAAG
TCCTCGTTGTGGATGATCAAGGCAAGCCAGTTGCGATTGGAGAGGAAGGGGAACTGCTGACCCGAGGGCCTTACACGCTT
AGCGGATATTACCGTGCGCCAGAGCATAATCTGCGGGCGTTTACGGATGAAGGGTATTATCGCAGTGGCGATCGCGTGGT
CGTCGATGCCAACGGTTACTTCACGGTCACTGGGCGGATAAAGGATGTGATCATTCGTGCTGGCGAAAACATTGCTGCTG
ATGAGTTAGAAGAACTCTTATTGTCGCATCCACAAATTGCCCAAGTAGCGGTGTTTCCCCTGCCAGATGCTCATTTAGGT
GAAAAAATCGCCGTCGCCGCCGTCATTCGAGGTCCCGAAATTATGTTGCGAGACATTCGGCAATTTCTCCAAGCCAAAGA
GATCGCCGCATTCAAACTTCCTGATGAACTGTTTGCGGTCAAATCGTTGCCAAAAACGGCCGTAGGCAAAATCGACAAGA
AGCGCATTTTAAGCACCATTCTGCCGTGA

Protein sequence : 
MVVATTETPKQILDGFVRKPSVQSEQYQAANLWRNSPLWQILHQGVGRHPDRIAVTDNHTSLSYLELANRVDRIAAGLRE
EGLVCGDSVVLQLANTLDFLVVFFALQRLGVVPVLALPAHGLVEIRHFMQLSGARVYIGSNHEKDDKALAIATQLQAELS
ISIRCYISGHFGQFSPLPECDAGDFTPAMVDPEHPALFLVSGGTTGLPKLIPRTHNDYLFNVEQCAKASEISAQDVYLAV
LPAAHNFTLGCPGILGVLNTGGKVVLTTNPSPDYCFELIEKQRITATALVPALAQLWTEATQWESTDRSSLRLMQVGGSK
LAYSDALEMQHAFPNALQQVFGMAEGLIACTRLGDDKEIIATRQGRPVSEWDEVLVVDDQGKPVAIGEEGELLTRGPYTL
SGYYRAPEHNLRAFTDEGYYRSGDRVVVDANGYFTVTGRIKDVIIRAGENIAADELEELLLSHPQIAQVAVFPLPDAHLG
EKIAVAAVIRGPEIMLRDIRQFLQAKEIAAFKLPDELFAVKSLPKTAVGKIDKKRILSTILP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE CAA21394.1 - Virulence HPI Protein 2e-92 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-92 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-92 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 47
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-92 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 47
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 7e-92 46
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-91 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VVMO6_04208 YP_004191433.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-105 48
VVMO6_04208 YP_004191433.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-104 46
VVMO6_04208 YP_004191433.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 9e-89 42