Gene Information

Name : VVMO6_04203 (VVMO6_04203)
Accession : YP_004191428.1
Strain :
Genome accession: NC_014966
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 1413934 - 1415571 bp
Length : 1638 bp
Strand : +
Note : -

DNA sequence : 
ATGAACTCTGTACAATCTGATTTCACTCCATGGCCAGAGCAGATGGCGGACGATTATCGCCGCCTTGGCTTATGGCAAGA
TAAAACGCTCTATCAGTATCTCAAGCAATCCATTATTCGCTACCCGACCAATATTGCCATTGTATGCAGTCAACAAAGCA
TCACATACGCTGAGCTTGAGCGAAAAATCCATGCGGCTGCCAACGGGTTTCGCTCGCTGGGCCTCGCTGAAGGCGATAAC
GTGATTCTGCAGATGACCAATATCGCCGAGTTCTATGTCAGTTACTTTGCGCTGATTCATCAAGGCATTCGCCCAATATT
GGCGTTACCTGCCCATCGTCACGCTGAGATTAGCTACTTCTGCCAACATGCCCAAGCCAAAGCGTATCTGATCGATGGCC
AAACTCGTGGTTTTGACTACCAAACACTGGCCGAGCAACTCCTCAAAGAGAACCCATGTTTGCGCCATGTCATCGTCAGA
GCCAATCACTCCGAGCTGCTGCAATCTCATTTCATCTCATTTGACGACTTTCGCGATGAACGAGAACTGTCCCCTGTCAG
TCACGCAAGTCAGGTTGCCTTTTTTCAACTTTCCGGCGGAACGACGGGCACTCCCAAATTGATCCCGCGTACGCACAATG
ATTATGCTTACAGTGTGGTCGGCAGTAACGCCATCTGTGGTTTTAATGAGTACACACGCTATCTTTGCGCGCTACCCGCT
GCGCACAATTTTCCGCTCAGTTCCCCTGGTTCGCTTGGGGTATTTTTCGCTGGTGGCACCGTTATCCTGACGCAAGACCC
AACGCCCAAAGCGGCATTTCCTCTGATTGAACGTCACAAAGTAACCGTATCGGCTCTGGTTCCCCCGTTAGCTTTGCTGT
GGATGGACGCCGCGCCACACGCACGCTACAACTTATCAAGCTTACAGTTAATCCAAGTTGGTGGTGCTAAGTTGAGCCAA
AGTGCGGCAAAAGCTTTGCCAAAAGCACTCAATTGCCAGCTTCAACAAGTGTTCGGCATGGCAGAAGGGCTAGTGAATTA
TACTCGGCTAGACGATCCGCTCGAGGTGATCATCGAAACGCAAGGTCGCCCTATATCCGCCCATGACCAAGTGAAAGTGG
TCAATGAAGCCGGTGAAGAGGTTGCGTGCGGAGAAGAAGGTTTTCTCCTTACCCAAGGGCCTTATACGATTCGCGGCTAC
TACCGAGCACCGGAGCACAATCAGCGTTCGTTCACTCACAACGGTTTTTATCGCACTGGCGATATTGTGAAGATAACAGA
GCAAGGCAATATCATCGTCACAGGCCGGGACAAAGATCAGATCAATCGCGGCGGTGAAAAAATCGCGGCGGAAGAAGTGG
AGAATCATTTACTGGGCCACAGTGCGATTCATGATGTGGCGTTGATTGCCATTCCCGACCGCTTGTTGGGTGAGCGAAGC
TGCGCAGTGATCGTCACCAAACGTCATCTCAATATCACAGGAACGGAACTAAAACGTTACTTACGCAGCAAAGGGTTGGC
GGACTATAAGATCCCCGATGTGATCCAATTTGCCGATGCTCTGCCCAAAACATCCGTAGGAAAGATCGACAAGAAACGCT
TGCGTGAATCTTACGCCCAGCTTGGTTTGAGTGCTTAG

Protein sequence : 
MNSVQSDFTPWPEQMADDYRRLGLWQDKTLYQYLKQSIIRYPTNIAIVCSQQSITYAELERKIHAAANGFRSLGLAEGDN
VILQMTNIAEFYVSYFALIHQGIRPILALPAHRHAEISYFCQHAQAKAYLIDGQTRGFDYQTLAEQLLKENPCLRHVIVR
ANHSELLQSHFISFDDFRDERELSPVSHASQVAFFQLSGGTTGTPKLIPRTHNDYAYSVVGSNAICGFNEYTRYLCALPA
AHNFPLSSPGSLGVFFAGGTVILTQDPTPKAAFPLIERHKVTVSALVPPLALLWMDAAPHARYNLSSLQLIQVGGAKLSQ
SAAKALPKALNCQLQQVFGMAEGLVNYTRLDDPLEVIIETQGRPISAHDQVKVVNEAGEEVACGEEGFLLTQGPYTIRGY
YRAPEHNQRSFTHNGFYRTGDIVKITEQGNIIVTGRDKDQINRGGEKIAAEEVENHLLGHSAIHDVALIAIPDRLLGERS
CAVIVTKRHLNITGTELKRYLRSKGLADYKIPDVIQFADALPKTSVGKIDKKRLRESYAQLGLSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 9e-105 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-105 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-105 47
ybtE CAA21394.1 - Virulence HPI Protein 9e-105 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-105 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 6e-105 47
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-105 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-104 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-105 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VVMO6_04203 YP_004191428.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-119 50
VVMO6_04203 YP_004191428.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 4e-113 47
VVMO6_04203 YP_004191428.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 6e-100 43