Gene Information

Name : Isop_0880 (Isop_0880)
Accession : YP_004178019.1
Strain : Isosphaera pallida ATCC 43644
Genome accession: NC_014962
Putative virulence/resistance : Unknown
Product : hydroxymethylpyrimidine synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1236984 - 1238414 bp
Length : 1431 bp
Strand : -
Note : COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: psl:Psta_1377 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: Phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; PF

DNA sequence :
ATGAACGCCTCCCTTGAACCGTCCACCCACGCCACCACGCCAGCTTACTCCCCCTTGTCGCCGCCATTGCCCCGGTTCCG
TTACGCCGGCCCAACCGGCATGACCCAGCTGCAGGCGGCCCGTGCGGGAACGATCACCCCCGAAATGGAATACGTGGCAG
CCCGCGAGGGATTGCCTCCCGAACTCATCCGCGCCGAGGTGGCCCGGGGCCGCATGGTCATCCCCGCCAATGTCAACCAC
TTGAAACTCGGCTTGCAACCCATGGCGATTGGATTGGCCGCCCGCTGCAAAATCAACGCCAACATCGGCAACTCAGCCGT
CACATCCGAGGTCGAGAACGAACTAGCCAAGCTTCGCGCCGCGATCGAACTTGGGGCCGACACGGTGATGGATCTGTCCA
CCGGCGCGGGGATTGACGAGATCCGCCAGGCGATCCTCGCCGCCAGTCCCGTCCCCATCGGCACGGTGCCGTTGTATCAA
GCGGTGCAGCAAGTCAAAAAGGTCGAAGACCTCAAACCTCAAGACTTCCTCGACATCGTGGAACACCAAGCCAAGCAGGG
GGTCGATTACATGACCCTTCACGCTGGCATCCTTCGCGACATGATCCCCCTCACGGCCGGGCGGGTCACCGGCATCGTCT
CGCGGGGCGGCTCGCTCATCGCTAAGTGGATGGTCGCGCACAAGGCTGAGAATCCCCTTTATACTCAGTTTGACCAACTC
TGCGAAATCATGCGGGCCTACGACGTGACCTGGAGCCTGGGCGACAGCCTGCGGCCCGGCTCGATCGCCGACGCCTCCGA
CAAAGCTCAGTTCGCCGAACTCAAGGTCCTGGGCCAACTAACCCGACGCGCTAAGGCGCTGGGGTGCCAAGTCATGGTCG
AAGGGCCGGGCCATGTGCCAATGGATCAAATCCCGGTCAACATGGAAAAACAGGCGTTCGAGTGCGAAGAAGCACCTTTC
TATGTGCTAGGACCGCTCGTCACTGACATCGCCCCCGGCTACGACCATATTACCTCGGCGATCGGCGCGGCCATCGCCGG
TTGGTATGGTGCGTCGATGCTCTGTTACGTCACCCCCAAAGAACACCTCGGTTTGCCTGAAGTCGATGATGTTCGCCAAG
GAGTGATCGCCTACAAGATCGCCGCCCACGCCGCCGACCTCGCCCGCAAGCGTCCAGGCGCGCGCGACCGCGACGACGCC
CTGTCCCACGCTCGCTACACCTTCGACTGGCGGCGTCAGTTCGCCCTTGCACTCGACCCTCAAACCGCTCAACGGATGCA
CGACGAAACCTTGCCACAAGAAGCGTTCAAGTCGGCTGCGTTTTGCTCGATGTGCGGTCCCAAGTTTTGTTCAATGAAGA
TCACCGAAGATGTTCGTCGACTCGTCGAAGTTGAGATCCAGGCCAAAGACCAACCCGTGACCGTCGGATGA

Protein sequence :
MNASLEPSTHATTPAYSPLSPPLPRFRYAGPTGMTQLQAARAGTITPEMEYVAAREGLPPELIRAEVARGRMVIPANVNH
LKLGLQPMAIGLAARCKINANIGNSAVTSEVENELAKLRAAIELGADTVMDLSTGAGIDEIRQAILAASPVPIGTVPLYQ
AVQQVKKVEDLKPQDFLDIVEHQAKQGVDYMTLHAGILRDMIPLTAGRVTGIVSRGGSLIAKWMVAHKAENPLYTQFDQL
CEIMRAYDVTWSLGDSLRPGSIADASDKAQFAELKVLGQLTRRAKALGCQVMVEGPGHVPMDQIPVNMEKQAFECEEAPF
YVLGPLVTDIAPGYDHITSAIGAAIAGWYGASMLCYVTPKEHLGLPEVDDVRQGVIAYKIAAHAADLARKRPGARDRDDA
LSHARYTFDWRRQFALALDPQTAQRMHDETLPQEAFKSAAFCSMCGPKFCSMKITEDVRRLVEVEIQAKDQPVTVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-121 60
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-121 60
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-117 57