Gene Information

Name : Isop_2864 (Isop_2864)
Accession : YP_004179978.1
Strain : Isosphaera pallida ATCC 43644
Genome accession: NC_014962
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 4180044 - 4181612 bp
Length : 1569 bp
Strand : -
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR011702: IPR006220: IPR001317: IPR 000991: IPR001674: IPR004739; KEGG: psl:Psta_2814 GMP synthase, large subunit; PFAM: GMP synthase domain protein; glutamine amidotransferase class

DNA sequence :
GTGGACCGCGTCTCGCCGCGCCCAGTTTTGGTGTTCGATTTCGGCTCTCAGTATGTCCAACTGCTGGCTCGACGCGCCCG
TGAGGCGGGTACGTTGGCGATGATCGTTCGTCACGATTTGCCTGTGGAACGGGTTCGGGAACTCAATCCGATCGGGTTGA
TCCTTTCAGGCGGACCGGCCAGCGTTTACGATCCCAGCGCTCCTCGTTGCGACCCCCGAATCTTCGACCTCGGTGTGCCG
ATCCTGGGAGTCTGCTATGGAATGCAACTGCTGTGCGACGCGCTGGGAACGCCGGGCGGGGTCCGCTCCGCTGAAACCCG
GGAATATGGCCGCACTCACTTGCATTTGCTCGAATCGGCAGCCAACGATCCACTCTTTACCGGAGTTCCCCCCGAATCGA
TCGTCTGGATGAGTCACGGCGATCAGGTGCGCGAGCTTCCGAATGGATTTCGGGCTCTCGCGCGCTCGGGCGATTGCCCA
CTGGCGGCGGTCGTCAAAACCGATCGACCAATCTATGGACTTCAGTTTCATCCCGAGGTGGTTCACACTGAATACGGCCA
AACCATTCTCAGCAATTTTCTCAAGCGGGTGTGCCACGCTCCGGGTGACTGGAACATGGGCACCTTTCTGGAGCGGGCCG
TCGAACGGATTCGTTGCCAGGTCGGCGAGGAGGGCCGGGTGGTCTGCGGACTCTCCGGTGGGGTGGATTCAGCGGTCGCC
GCGGCGCTTCTGGCGCGGGCCATCGGCGATCGGGTGGTCTGCGTGCTGGTGGACAACGGGTTGTTACGGGCCGGCGAGCG
CGACGCAGTCGTCGCCGCCTTCCGCGACCACTTCGCCGTCGAATTGCGGGTCATCGACGCAGCCGACCGCTTCCTGGAAC
GGCTCCAAGGCGTCACCGATCCCCAGGAAAAACGCATCCGAATCGGCCATTTATTCATTGAACTCTTCCGCAACGAAGCC
GCTGCCATCCCCCACGCCCGTTTTCTGGCGCAAGGGACGCTCTATCCCGACGTGATTGAGAGCGGAGGGGGAGCCGACGG
CCCAGCGGCCACGATCAAACATCACCACAACGTTGGAGGTCTGCCCGCCGAGTTGGGTCTGGAACTGATCGAACCCTTGC
GCGACCTGTTCAAGGACGAGGTCCGCAAGCTCGGGATCGAACTCGGTTTGCCCGCCTGGTTTGTTGGCCGCCACCCCTTT
CCGGGTCCCGGTTTGGCGGTTCGCTGCTTGGGGCCGGTCGAACCTCGCCGCCTCGAAATCCTCCGACGCGCCGACGCGAT
CTTCCTGGAGGAACTCCGCGCTGCGGGCCTCTACGACCGCACCGGCCAGGCCTTCGCCGTGCTTCTGCCGGTCAAGTCGG
TCGGCGTCATGGGCGACGGTCGAACCTATGACGAAACCATCGTCCTCCGTTCCGTCGATACTGACGACTTCATGACCGCC
GACTGGTCCCGATTGCCCCATGACCTGCTCGCCAAGGTTTCCACCCGGATCGTCAACGAGGTCCCAGGTGTCAACCGAGT
CGCCTACGATATCACCAGCAAACCCCCCGGCACGATTGAGTGGGAATGA

Protein sequence :
MDRVSPRPVLVFDFGSQYVQLLARRAREAGTLAMIVRHDLPVERVRELNPIGLILSGGPASVYDPSAPRCDPRIFDLGVP
ILGVCYGMQLLCDALGTPGGVRSAETREYGRTHLHLLESAANDPLFTGVPPESIVWMSHGDQVRELPNGFRALARSGDCP
LAAVVKTDRPIYGLQFHPEVVHTEYGQTILSNFLKRVCHAPGDWNMGTFLERAVERIRCQVGEEGRVVCGLSGGVDSAVA
AALLARAIGDRVVCVLVDNGLLRAGERDAVVAAFRDHFAVELRVIDAADRFLERLQGVTDPQEKRIRIGHLFIELFRNEA
AAIPHARFLAQGTLYPDVIESGGGADGPAATIKHHHNVGGLPAELGLELIEPLRDLFKDEVRKLGIELGLPAWFVGRHPF
PGPGLAVRCLGPVEPRRLEILRRADAIFLEELRAAGLYDRTGQAFAVLLPVKSVGVMGDGRTYDETIVLRSVDTDDFMTA
DWSRLPHDLLAKVSTRIVNEVPGVNRVAYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-122 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-122 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-122 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-109 52