Gene Information

Name : Deima_0182 (Deima_0182)
Accession : YP_004169511.1
Strain : Deinococcus maricopensis DSM 21211
Genome accession: NC_014958
Putative virulence/resistance : Virulence
Product : (2,3-dihydroxybenzoyl)adenylate synthase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 209151 - 210764 bp
Length : 1614 bp
Strand : +
Note : COGs: COG1021 Peptide arylation protein; InterPro IPR000873; KEGG: avn:Avin_21210 enterobactin synthetase component E (2,3-dihydroxybenzoate-AMP ligase); PFAM: AMP-dependent synthetase/ligase; PRIAM: (2,3-dihydroxybenzoyl)adenylate synthase; SPTR: Enterob

DNA sequence :
GTGAACGCCGACTTCACGCCCTGGCCACCCGACGTGGCCGCCGAGTACCGCCGACTCGGGTACTGGCGCGGCGAGACGTT
CAGCGCGTGGCTGGACCGCACCAGCCGCCTGCACGCGCACCGCACCGCGCTGATTCACGGTGACGACACCGTCACGTACG
CTGACCTGCACGCCCAGGCCGAGCGGTACGCGACGCTGTTCGCCCGCAGCGGCCTGCAGGCCGGGGACTGCGTGGTCGTG
CAGCTCCCGAACCGGGCGGCGTTCTTCCCCGTATGCTTCGGCCTGATGCGTGTCGGCGCGGCGCCCATCATGGCGCTCCC
CGCGCACCGCGAGCGCGAAATCACCTTCTTCTGCGCGCACACTGACGCGCGCGCGTACGTCACCGTCGACGAGCACGGCG
GGTTCGACCACCGCCGCCTCGCGCGCGCCGCCGTCGCCGCCGCCCCCAGCCTCCGGCACGTGTTCATCCTCGGGGACGCC
GCGGAATTCACGCCGCTGCGCGCCCCGGACGAGGCGGGCGACCTCCCCCCCACCCCGGTGGACGCCTCCACGGTGGCGCT
CTACCAGCTGTCCGGCGGAAGCACCGGCACGCCAAAACTCATTCCGCGCACGCACGACGACTACCTGTACAGCGTCCGCG
CCAGCGCGGACATCTGCGCGCTCGGCCCGGACACCGTGTACCTCGCGGCGCTGCCGCTCGCGCACAACTTCCCGCTCAGC
TCCCCCGGCACGCTCGGCGTGCTCCACGCGGGCGGCACCGTCGTGATCGCCCCCGACCCGACGCCCACCACGACCTTCCC
GCTCATCGAGCGGCACGGCGTGACCATGGCGGCGCTCGTGCCCGCGCTGCTGCTCGTGTGGCTGCAGCACGCCCGCACGC
ACGGCACGCCCGGCTGCCTGCAACTCCTGCAGGTGGGCGGCGCGCCCCTCGCCGCGGATGTCGCGCGGCAGGTGCCGGAC
GTGCTCGGCTGCGCCCTGCAGCAGGTGTTCGGCATGGCCGAAGGGCTCGTGAACTACACCCGTCCGGGCGACCCGGCGTC
GCTCGTGTACCACACGCAGGGCCGCCCCATCAGCCTGCACGACGAGGTCCGCATCGTGAACGACGACGACGAGGACGTCC
CCGCCGGCGTGCCCGGGCACCTGCTCACGCGCGGCCCCTACACGATCCGTGGGTACTTCCGCGCGGACGACCACAACCGC
CGCGCGTTCACGCCCGAAGGGTACTACCGCACCGGCGACGTCGTCACCCGCCGCGCCGACGGGTACCTGGAAGTCACCGG
GCGGCACAAGGACCAGATCAACCGCGCGGGCGAGAAGGTCGCCGCCGAGGAGATCGAGCACGTGCTGCTCACGCACCCGG
CCGTGCACGACGTCGCCGTGGTCGGCCTCCCGGACGCGTGGCTCGGCGAACGCACCTGCGCGTTCGTGCAGCTCACAGGC
GCGGCCACGCCGCGCCTCGCGCTGGACCTCAAGGCGCACGTGCGCGCCGCCGGCCTTGCCGACTACAAAACCCCCGACCT
GATCGAATTCGTCGATGCCCTGCCCCGCACGGCGTTCGGCAAGACCAACAAGGTCGCCCTGCGCGCCCGCCTGAACGAAC
GGAGCCCCCAATGA

Protein sequence :
MNADFTPWPPDVAAEYRRLGYWRGETFSAWLDRTSRLHAHRTALIHGDDTVTYADLHAQAERYATLFARSGLQAGDCVVV
QLPNRAAFFPVCFGLMRVGAAPIMALPAHREREITFFCAHTDARAYVTVDEHGGFDHRRLARAAVAAAPSLRHVFILGDA
AEFTPLRAPDEAGDLPPTPVDASTVALYQLSGGSTGTPKLIPRTHDDYLYSVRASADICALGPDTVYLAALPLAHNFPLS
SPGTLGVLHAGGTVVIAPDPTPTTTFPLIERHGVTMAALVPALLLVWLQHARTHGTPGCLQLLQVGGAPLAADVARQVPD
VLGCALQQVFGMAEGLVNYTRPGDPASLVYHTQGRPISLHDEVRIVNDDDEDVPAGVPGHLLTRGPYTIRGYFRADDHNR
RAFTPEGYYRTGDVVTRRADGYLEVTGRHKDQINRAGEKVAAEEIEHVLLTHPAVHDVAVVGLPDAWLGERTCAFVQLTG
AATPRLALDLKAHVRAAGLADYKTPDLIEFVDALPRTAFGKTNKVALRARLNERSPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-90 45
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-90 45
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-90 45
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-90 45
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-90 45
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-90 45
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-90 45
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-90 45
ybtE CAA21394.1 - Virulence HPI Protein 2e-90 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Deima_0182 YP_004169511.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG1817 Protein 4e-96 48
Deima_0182 YP_004169511.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0168 Protein 6e-110 48
Deima_0182 YP_004169511.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0932 Protein 3e-99 44