Gene Information

Name : Isop_3753 (Isop_3753)
Accession : YP_004169319.1
Strain :
Genome accession: NC_014957
Putative virulence/resistance : Virulence
Product : NAD-dependent epimerase/dehydratase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0451
EC number : -
Position : 38601 - 39566 bp
Length : 966 bp
Strand : +
Note : COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904: IPR001509; KEGG: rrs:RoseRS_2395 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epime

DNA sequence : 
ATGACCACGATCACCATCGCCACCCCCACGGCGCCGCGTCGCGCGTTGGTGACCGGCGGGGCGGGCTTCATTGGCTCGCA
TTTGGTCGAGGCGTTGCTGGCGAGGGGATGGCAGGTTCGGGTCCTGGACAACTTCTCCAGCGGCCAGCTCGCCAACCTCA
AGCCGTGGCTGGACCGCATCGAGTTGCTGGAGGGGGACGCGGCCGATCCGGTCCTGGCGGCGCGGGCGTGCCGGGAGGTC
GAGGTGGTCTTCCACCAGGCGGCGATCCCCAGCGTGCCCAAGTCGGTGTTGGACCCCATCGCCACCCACCACGCCGGCCC
CACGGCGACCTTGACGATGCTCCAGGCCGCCCGCGCTGCTGGGGCGCGGCGGTTCATCTTTGCCGCCAGCAGCTCGGCCT
ACGGCGATACCCCCACCTTGCCCAAGCACGAGGCTATGCTTCCACAACCGTTGAGTCCCTACGCCGCCAGCAAGCTCGCC
GGCGAACACTATGTGGCCGCCTTCGCCCGCTCGATGGGGTTGGATGGGGTCTCATTGCGTTATTTCAACATCTTTGGACC
CCGCCAGGACCCCTCCAGCCCTTACAGTGGGGTGATCTCGCGGTTCCACCTGGTCATGAGCCACGGCGCCCCCCCCACCA
TCTACGGCGACGGCACCCAAACCCGCGACTTCACTGCCGTGGCCAACGCGGTTCACGCCAACCTGCTGGCCGCCGACCAC
CCCCAGGCTCTGCGGGGCGCGGTGCTCAATGTCGGCACTGGTCAACGTACCTCGCTGCTGGACCTAGTGGCCGCCCTCAA
CCGCCTCCTCCAGCTCGATCCGCCGCTCCAACCCCGCTACGAGCCGCCCCGACCCGGCGACATCGCCCACTCCCTCGCCT
CACTTGAGCTGGTCCATGCCACCCTCGGCTACCAACCCCTCGTCTCCTTCGAGGACGGACTCCGCGCGTTGGTGCAATCC
TCGTGA

Protein sequence : 
MTTITIATPTAPRRALVTGGAGFIGSHLVEALLARGWQVRVLDNFSSGQLANLKPWLDRIELLEGDAADPVLAARACREV
EVVFHQAAIPSVPKSVLDPIATHHAGPTATLTMLQAARAAGARRFIFAASSSAYGDTPTLPKHEAMLPQPLSPYAASKLA
GEHYVAAFARSMGLDGVSLRYFNIFGPRQDPSSPYSGVISRFHLVMSHGAPPTIYGDGTQTRDFTAVANAVHANLLAADH
PQALRGAVLNVGTGQRTSLLDLVAALNRLLQLDPPLQPRYEPPRPGDIAHSLASLELVHATLGYQPLVSFEDGLRALVQS
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviC NP_458739.1 Vi polysaccharide biosynthesis protein, epimerase Virulence SPI-7 Protein 2e-33 46
tviC NP_807944.1 VI polysaccharide biosynthesis epimerase Virulence SPI-7 Protein 2e-33 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Isop_3753 YP_004169319.1 NAD-dependent epimerase/dehydratase VFG0430 Protein 7e-34 46