Gene Information

Name : Nitsa_1731 (Nitsa_1731)
Accession : YP_004168726.1
Strain : Nitratifractor salsuginis DSM 16511
Genome accession: NC_014935
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 1731416 - 1732699 bp
Length : 1284 bp
Strand : -
Note : COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: abu:Abu_0661 UDP-hexose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation

DNA sequence :
ATGGCAAAAATAGCCGTAATAGGGCTCGGGTATGTCGGCTTGCCGCTGGCACATGCCTTTAGTGAAAAATATCCGGTGAC
AGGCTTCGATATCGCCCAATGGCGGATCGATGAGCTACGCCGCGGCTACGATCGGACGCTGGAGCTGAGTGAAGCGCAAG
TCAAAGAGGCGATCGCCAACGGAATGCAATTTACCAATAAGCTCGATGAGATTGCGGAGTGCAATGTCTACATCGTGACC
GTACCGACCCCCATCGACAAACACAAGCGCCCCGATCTCACCCCTCTGATCAAAGCGAGTGAATCGATCGGAAAGGTGCT
CAAGCCCGGCGATATCGTCATCTACGAATCCACCGTCTACCCCGGTGCCACCGAAGAGGTCTGTGTCCCCATCCTCGAAA
AAGTCTCCGGTCTGAAATATATCTCATCCGACTCACCAACGACCGAAAATGGTTTCTACTGCGGCTATAGCCCCGAACGT
ATCAACCCCGGCGACAAGGAGCATACGGTTACGAAGATTCTGAAAGTCACTTCCGGCTCCACCCCCGAGATCGCCAAAAA
GATCGATGAGCTCTACGCCAGCGTGATTACTGCCGGAACCCACCTGGCTCCCAGTATCAAAGTGGCCGAAGCGGCGAAGG
TCATCGAAAACTCCCAAAGAGATATCAATATCGCCTTCGTCAACGAACTGGCCATCATTTTCAACAAACTCGGCATCGAT
ACCCAGGCGGTGCTGGAGGCGGCGGGGACGAAATGGAACTTCCTCCCCTTCCGGCCGGGTCTGGTGGGTGGCCACTGCAT
CGGGGTCGATCCCTACTATCTGACCCACAAAGCGCAAGAAGTCGGCTATTATCCCGAGATCATCCTCGCCGGACGCCGGC
TCAATGATCAGATGGGGATCTATGTCGCCAATCAGGTCGTCAAACTGATGATCAAAAAAGGGCAAAGAATCGAAGGGGGC
AAAGTGCTGGTCCTGGGCATCACCTTCAAAGAAAATTGCCCCGATATCCGCAACTCTCGTGTCATTGATGTTATTAGAGA
GTTGCAAGAGTTCGGCACCCAGGTCGATGTCTTTGACCCCTGGGCCGATCCGGAAGAGGTGAAGCACGAGTATGGCATCT
CTCTTGTTCCCGAAGAGAGTTTACAGCTCGATGCTTACGATGCAATTGTGCTTGCGGTTGCTCATAATGAGTTTAAGAAT
TTGGATCTCGAGAGTGATGAGCATCGAGTAGTCTACGATATCAAGTCGATGCTCGATGGTAAGAGAGTGGATGGAAGGCT
GTAA

Protein sequence :
MAKIAVIGLGYVGLPLAHAFSEKYPVTGFDIAQWRIDELRRGYDRTLELSEAQVKEAIANGMQFTNKLDEIAECNVYIVT
VPTPIDKHKRPDLTPLIKASESIGKVLKPGDIVIYESTVYPGATEEVCVPILEKVSGLKYISSDSPTTENGFYCGYSPER
INPGDKEHTVTKILKVTSGSTPEIAKKIDELYASVITAGTHLAPSIKVAEAAKVIENSQRDINIAFVNELAIIFNKLGID
TQAVLEAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQEVGYYPEIILAGRRLNDQMGIYVANQVVKLMIKKGQRIEGG
KVLVLGITFKENCPDIRNSRVIDVIRELQEFGTQVDVFDPWADPEEVKHEYGISLVPEESLQLDAYDAIVLAVAHNEFKN
LDLESDEHRVVYDIKSMLDGKRVDGRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-124 61
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-124 61
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 5e-109 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nitsa_1731 YP_004168726.1 nucleotide sugar dehydrogenase VFG0431 Protein 3e-124 61