Gene Information

Name : Bache_2159 (Bache_2159)
Accession : YP_004161714.1
Strain : Bacteroides helcogenes P 36-108
Genome accession: NC_014933
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2637585 - 2638865 bp
Length : 1281 bp
Strand : +
Note : COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: pdi:BDI_2219 UDP-glucose-6 dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisat

DNA sequence :
ATGGACTCAATAAAAATTTGCGTAATCGGTCTCGGTTATGTAGGGCTACCTTTGGCCCGTCTTTTTTCCACTAAGTATCA
AACCATTGGTTTTGATATGGACCAAAAGCGTGTGGATTACTTAATGTCTGGCCATGATTCTACATTTGAAGTGTCTGATG
AATTGTTACAAGATGCCATTTACAATCACGGGTTTATATGTACTACAAATATGGATAAAATTCGTGACTGCAATTTTTAT
GTGGTTGCAGTTCCTACTCCTGTGGATGACAATAATCGTCCAGATCTTCGTCCTTTATGGGGAGCCAGCGAGACGGTGGG
TAAAGTTATCAAGAAAGGTGACATTGTGGTTTATGAATCTACTGTTTATCCTGGGGTCACTGAGGAGGAATGCTTGCCTG
TGGTGGAACGTGTATCAGGTTTGAAGTTTAATGAAGACTTCTTTGCCGGTTATTCTCCCGAACGTATCAATCCCGGAGAT
AAATTTCATACGGTAGAGAAGATAAAAAAAGTAACATCAGGTTCTACTCCGGAGATTGCAGATGTTGTGGATGCGGTTTA
TAATTCGGTATTGGTGAATGGCACTCATAAAGCGCCAAATATCAAGGTGGCGGAAGCATCGAAGATCATAGAGAATTCTC
AGCGTGATGTGAATATCGCTTTTATGAATGAATTGGCGAAGATATTCAATGCAATGGGTATTGATACTAATGATGTGATA
GAGGCTGCTGCCTCTAAATGGAACTTTATCAAGTTGAAACCGGGCTTGGTTGGTGGACATTGTATAAGTGTGGATCCTTA
TTATTTGATTCAGAAAGCACAAGTGTATGGCGTGCTGCCCCGTGTGATGTTTTCTGCACGTCGCTTGAATGACGGTATGG
GTGATTATGTAGGCAATCAAGCGATAAAGTTGATGAACAAGAAAGGGGTGTTGGTTAAGGATAGTAAAATTTTGATTTTA
GGTTTCACATTTAAGGAAAATTGTCCGGATGTGCGTAACACCAAGGTTATTGATATATACCACACATTAGAGGAATATAC
AAAAAACATCACCGTATATGATCCTTGGGCAGATGCTGATAGGGTTAAATATGAGTATGGTGTGAATTTGTCTGCCAATT
CGTTCGATTCATTGAAGGGAAAATTTGATGCCGTGGTATTGGCTGTAGCTCATAAAGAATTTGTGTCCATTGATATACGC
TCATTTCTGAAGGATAAAAATGGGGTAGTATATGATGTAAAGGGTGTTTTAAATAGAGAAGTAGTTGATGGAAGATTATA
A

Protein sequence :
MDSIKICVIGLGYVGLPLARLFSTKYQTIGFDMDQKRVDYLMSGHDSTFEVSDELLQDAIYNHGFICTTNMDKIRDCNFY
VVAVPTPVDDNNRPDLRPLWGASETVGKVIKKGDIVVYESTVYPGVTEEECLPVVERVSGLKFNEDFFAGYSPERINPGD
KFHTVEKIKKVTSGSTPEIADVVDAVYNSVLVNGTHKAPNIKVAEASKIIENSQRDVNIAFMNELAKIFNAMGIDTNDVI
EAAASKWNFIKLKPGLVGGHCISVDPYYLIQKAQVYGVLPRVMFSARRLNDGMGDYVGNQAIKLMNKKGVLVKDSKILIL
GFTFKENCPDVRNTKVIDIYHTLEEYTKNITVYDPWADADRVKYEYGVNLSANSFDSLKGKFDAVVLAVAHKEFVSIDIR
SFLKDKNGVVYDVKGVLNREVVDGRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 9e-103 55
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 9e-103 55
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-92 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bache_2159 YP_004161714.1 nucleotide sugar dehydrogenase VFG0431 Protein 4e-103 55