Gene Information

Name : clpB (BARCL_1183)
Accession : YP_004159425.1
Strain : Bartonella clarridgeiae 73
Genome accession: NC_014932
Putative virulence/resistance : Virulence
Product : ATP-dependent clp protease, atp-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1324478 - 1327069 bp
Length : 2592 bp
Strand : -
Note : -

DNA sequence :
ATGAATTTGGAAAAATATAGCGAACGGCTTCAAGGTTTTTTACAAGCAGCGCAAAGCAGTGCTCTTTCTTCTGATCATCA
GCAGTTTATGCCTGAACATTTCTTGAAAGTGCTCTTAGAAGATAGTCAAGGATTAGCAGTTTCTTTGATCCAAAAAGCAG
GAGGAAATTTGCCTGCTATTCAAAAAGAACTCAAAGAAGCCCTCGATGCTTTGCCAAAAGTACAAGGCGGAAATGGACAA
CTCTATATGTCTCAGCCTTTGGCAAAAGTCTTCGCAAAAGCAGAAGAAATTGCTCAAAAAGCAAACGATCAATTTGTGAC
AGTGGAACGTGTTTTACAAGCTTTACTTCTCGAAAAAAGTGCAAAAACAGCCGACATTTTGACAATAGGAGGGGTGAAAG
CTCAAGAGCTTGAGCAAGTCATCAATACAATGCGAAAGGGAAAAACTGCAACAAGTCGTCATGCCGAAAGCCAATATGAA
GCCTTGGAAAAATATGCCCGTGATTTAACAAAAGAAGCACGGGAAGGAAAACTCGATCCTGTGATTGGACGAGAAGAAGA
AATCAGAAGGACTATTCAAGTCTTATCACGTCGAACCAAAAATAATCCTGTGCTAATCGGAGAACCAGGAGTCGGGAAAA
CCGCCATCGTCGAAGGATTAGCGCTCCGCATTGTCAATGGTGATGTGCCCGAAACATTGCGTGATAAACAACTCTATGCT
CTCGATATGGGAGCTCTTATCGCTGGGGCAAAATATCGAGGTGAATTTGAAGAACGTTTGAAAGCTGTTCTCACAGATGT
TCAAGCCGAAAATGGACAAATTATTCTCTTCATCGATGAATTACATAATCTCGTCGGAGCCGGGAAATCCGATGGACCTA
TGGATGCTTCTAATTTGCTCAAACCCGCTCTCGCGCGTGGTGAACTCCATTGTGTGGGTGCTACAACGCTCGATGAATAT
CGAAAATATGTCGAAAAAGATGCTGCTTTAGCTCGACGTTTCCAACCCGTCTTCGTTCCTGAGCCAACCGTCGAGGACAG
TATCTCTATCTTGCGAGGAATCAAAGAAAAATACGAACAACATCACAAAGTACGATTGGCTGACAGTGCTTTGATTGCTG
CTGCACGATTGTCTCAACGCTATATTGCCGATCGTTTCTTGCCCGATAAAGCTATCGATTTGATCGATGAAGCCGCCGCA
CGTTTGCGGATGCAGGTCGATTCAAAACCAGAAGAACTCGATGCAATCGATCGACGCATCATGCAGTTGAAAATCGAACA
GGAAGCTTTGAAAACAGAAGTTGATCCCGCAACAAAAGAACGCTTGAAAACTGTCAAAGCCGAACTCGAAACTTTGGAAA
AAAGCTCAACAGAAATGACACAAGCTTGGCAAGCCGAAAAACAAAAATTAGGCTATGCTGCCGATCTGAAAAAACAACTC
GAAGAAGCACGAAATGCTTTGGCTATTGCTCAACGAAATGGACAGTTCCAACGTGCTGGTGAACTTGCATATAGTGTCAT
TCCTGAACTCGAAAAACAACTCAATGTCGCAGAAAATGACGACCAACAAAATAATCTGGTCGAAGAAATCGTTACTACAG
AGCATATTGCTCAAATCGTTTCTCGTTGGACAGGAATCCCCGTCGATCGGATGCTCGAAGGTGAACGAGAAAAATTATTG
CGGATGGAAGACGAAATCAGTAACCGAGTGGTGGGGCAAACCGAAGCCGTACAGGCTATCGCACGAGCTGTACGACGCGC
ACGCGCCGGATTACAAGATCCTAACCGCCCTATCGGCTCCTTTATGTTCCTAGGACCAACAGGGGTCGGAAAAACAGAAC
TCACAAAAGCTCTCGCTGCTTTTCTCTTCCAAGATGATCAGGCTATGTTGCGGATCGATATGTCCGAATATATGGAAAAG
CATGCCGGAGCACGATTGATCGGTGCTCCTCCAGGATATATCGGATATGAAGAAGGAGGGATCCTCACAGAAGCTGTTAG
ACGTAGACCATATCAGGTCATTCTCTTCGACGAAATTGAAAAAGCGCATCCCGATATTTTTAATCTCCTTCTTCAAGTGC
TTGATGAAGGACGATTGACAGATAGTCAAGGACGAACCGTCGATTTTCGAAATACCGTCCTCATTATGACTTCTAATCTC
GGAGCCGAGAGCTTGACAGCATTATCGGAAGGACAAATAACACAGCAAGCAAAAGAAGAAGTGATGCAAGTAGTCAAAGC
TGCCTTCCGACCAGAATTCCTTAATCGCGTCGATGAAATTATCCTCTTTCAAAGATTACAACGCAAAGATATCGAAGCAA
TCGTCGATATTCAAATTCAACACTTACAAAATTTGCTCAGTGAACGCAAAATTACCTTGCAGATCAAACCAGAAGCCCGA
ACGTTGCTCGCTCATAAAGGCTATGATCCCCTCTATGGAGCTCGGCCGTTAAAACGAATGATGCAAAGAGAAATTCAGGA
TCCCCTCGCAGAAAGCCTCTTAAAGGGGATAATCCGTGATGATACAACCGTGACGATTGCAAAAGAAGGAGAGCAATTGA
TTTTTTCCTCTATAACAGAAAAAGAAAAATAA

Protein sequence :
MNLEKYSERLQGFLQAAQSSALSSDHQQFMPEHFLKVLLEDSQGLAVSLIQKAGGNLPAIQKELKEALDALPKVQGGNGQ
LYMSQPLAKVFAKAEEIAQKANDQFVTVERVLQALLLEKSAKTADILTIGGVKAQELEQVINTMRKGKTATSRHAESQYE
ALEKYARDLTKEAREGKLDPVIGREEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPETLRDKQLYA
LDMGALIAGAKYRGEFEERLKAVLTDVQAENGQIILFIDELHNLVGAGKSDGPMDASNLLKPALARGELHCVGATTLDEY
RKYVEKDAALARRFQPVFVPEPTVEDSISILRGIKEKYEQHHKVRLADSALIAAARLSQRYIADRFLPDKAIDLIDEAAA
RLRMQVDSKPEELDAIDRRIMQLKIEQEALKTEVDPATKERLKTVKAELETLEKSSTEMTQAWQAEKQKLGYAADLKKQL
EEARNALAIAQRNGQFQRAGELAYSVIPELEKQLNVAENDDQQNNLVEEIVTTEHIAQIVSRWTGIPVDRMLEGEREKLL
RMEDEISNRVVGQTEAVQAIARAVRRARAGLQDPNRPIGSFMFLGPTGVGKTELTKALAAFLFQDDQAMLRIDMSEYMEK
HAGARLIGAPPGYIGYEEGGILTEAVRRRPYQVILFDEIEKAHPDIFNLLLQVLDEGRLTDSQGRTVDFRNTVLIMTSNL
GAESLTALSEGQITQQAKEEVMQVVKAAFRPEFLNRVDEIILFQRLQRKDIEAIVDIQIQHLQNLLSERKITLQIKPEAR
TLLAHKGYDPLYGARPLKRMMQREIQDPLAESLLKGIIRDDTTVTIAKEGEQLIFSSITEKEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-103 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_004159425.1 ATP-dependent clp protease, atp-binding subunit ClpB VFG2076 Protein 6e-116 41
clpB YP_004159425.1 ATP-dependent clp protease, atp-binding subunit ClpB VFG2084 Protein 4e-110 41