Gene Information

Name : Varpa_5556 (Varpa_5556)
Accession : YP_004157821.1
Strain : Variovorax paradoxus EPS
Genome accession: NC_014931
Putative virulence/resistance : Virulence
Product : two component sigma-54 specific Fis family transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 6051030 - 6052385 bp
Length : 1356 bp
Strand : +
Note : KEGG: aav:Aave_0172 two component, sigma54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase

DNA sequence :
ATGGCGCACCTGCTGATCGTCGATGACGACGATGCCTTTCGCGACACGCTGGCCGAGACGCTGCAGGGCCTCGGCCACGA
CGTGATCGCCGCGGCCGGCGGCGCCGAGGCGATGGAGACGCTGGCGCGCGGACGCTTCGACGCCGTGTTCCTCGACCACC
GCATGCCCGGCATGGACGGCCTGCAGACGCTCGCCGCCATGCAGGCGCGGCTGGTGCACCTGCCGCCGGTGATCGTGCTC
ACCGCGTTCGCGAGCGCGGGCAACACCATCGAGGCGATGCGCCTGGGCGCCTTCGACCATCTGGCCAAGCCGATCAGCCG
CGAGGCGGTGCGCGAAGTGCTGGAACGCGCGCTGCAGCAGCGGACGACCGCAACGCCGTCGAGCGCCCCGGCGGAAGAAG
ACGACAGTGGCGGCGACTTGATCGGCCCTGGCCACGCGATGCGCGAAGTGCACAAGCGCATCGGCCTGGCCGCGGCGAAT
TCGATGCCGGTGCTGGTGCTCGGCGAAACGGGCACCGGCAAGGAAATGGTAGCGCGCGCGCTGCACCGCCATTCGGCACG
CGCCGACCGGCCCTTCGTGGCTATCAACTGCTCGGCCATTCCGAAGGAGCTGCTCGAAAGCGAACTCTTCGGCCATGTGC
GCGGCGCGTTCACGGGTGCCACGGGCGAGCGCCCGGGATGCTTTCGCGCGGCCGACGGCGGCGTGCTGCTGCTCGACGAG
ATCGGCGACATGGCGCTGGACATGCAGGCCAAGATCCTGCGCGCACTGCAGGAGGGCGAGGTCACGCCGCTGGGCAGCCA
CAGAACGATCAAGGTCGACGTGCGCGTGATCGCCGCGACGCACCGCGACTTGGCCGCCGCAGTGCGCGAGGGGCGCTTTC
GGGAAGACCTGCTCTACCGGCTCGATGTGCTCTCGATCCGCCTGCCGCCGCTGCGCGAGCGGCTGGCCGACATCATTCCG
CTGGCCGAGCACTTCCTGCGTCGCGCGGCAACGCCAGAGGCACCGAAGGCGCTGTCCGCCGACGCCGCGCAGCGGCTGCT
GAGCCACCCCTGGCCCGGCAACGTGCGCGAGCTGCGCAATGTGATGGAGCGTTGTCAGGCGCTGGTGCGCCACCGCGTGA
TCGGCGGCGCGGACTTGGCTGCAGCACTGGGCACAGCGCGCCCCGGCGAGACCGAGCAGACGCTCCCGGCCGGCTGGCTC
GACGCCGAGCTGCCCGCCGCCGTGGAGCGGCTGGAGCGGCTGCTGATCGCGAACGCGCTCGCAGAGTCCGGGGGCAATCG
CGCCGAGGCTGCACGCCGGCTGGGCATTCACCGGCAGTTGCTCTACCGCAAGCTCACCCAGCACGGCCTTGAGTAA

Protein sequence :
MAHLLIVDDDDAFRDTLAETLQGLGHDVIAAAGGAEAMETLARGRFDAVFLDHRMPGMDGLQTLAAMQARLVHLPPVIVL
TAFASAGNTIEAMRLGAFDHLAKPISREAVREVLERALQQRTTATPSSAPAEEDDSGGDLIGPGHAMREVHKRIGLAAAN
SMPVLVLGETGTGKEMVARALHRHSARADRPFVAINCSAIPKELLESELFGHVRGAFTGATGERPGCFRAADGGVLLLDE
IGDMALDMQAKILRALQEGEVTPLGSHRTIKVDVRVIAATHRDLAAAVREGRFREDLLYRLDVLSIRLPPLRERLADIIP
LAEHFLRRAATPEAPKALSADAAQRLLSHPWPGNVRELRNVMERCQALVRHRVIGGADLAAALGTARPGETEQTLPAGWL
DAELPAAVERLERLLIANALAESGGNRAEAARRLGIHRQLLYRKLTQHGLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 2e-62 41
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 2e-62 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Varpa_5556 YP_004157821.1 two component sigma-54 specific Fis family transcriptional regulator BAC0467 Protein 4e-74 43
Varpa_5556 YP_004157821.1 two component sigma-54 specific Fis family transcriptional regulator BAC0089 Protein 5e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Varpa_5556 YP_004157821.1 two component sigma-54 specific Fis family transcriptional regulator VFG1249 Protein 4e-72 46
Varpa_5556 YP_004157821.1 two component sigma-54 specific Fis family transcriptional regulator VFG1214 Protein 4e-72 43
Varpa_5556 YP_004157821.1 two component sigma-54 specific Fis family transcriptional regulator VFG0116 Protein 2e-63 41