Gene Information

Name : Varpa_4858 (Varpa_4858)
Accession : YP_004157130.1
Strain : Variovorax paradoxus EPS
Genome accession: NC_014931
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 5276953 - 5278671 bp
Length : 1719 bp
Strand : +
Note : TIGRFAM: urease, alpha subunit; KEGG: vap:Vapar_4243 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein

DNA sequence :
ATGGCCACCATCGGGCGACGCGCCTATGCAGAAATCTTCGGCCCCACCGTGGGCGACCGGGTCCGCCTTGCAGACACCGA
GCTGCTGATCGAAGTCGAGGCCGACTACACGCTGCGTGCCGGCGGCTACGGCGAAGAAGTGAAGTTCGGCGGCGGCAAGA
CGATTCGCGACGGCATGGCGCAATCGCAGCGCACCCGCGCGCAAGGCGCCGTCGACACCGTGCTCACCAACGCGCTCATC
CTCGACCACTGGGGCATCGTGAAAGCCGACATCGGGCTCAAGGACGGCCGCATCGCCGCCATCGGCAAGGCCGGCAACCC
CGACGTGCAACCGGGCGTGGACATCGTCATCGGCCCGGGCACCGAAATCATCAGTTGCGAAGGCAACATCGTCACCGCGG
GCGGCATCGACAGCCACATCCACTTCATCTGCCCGCAGCAGATCGAAGAGGCGCTGTCTTCCGGCGTGACGACGATGCTC
GGTGGCGGCACCGGCCCCGCCACCGGCACCTTCGCGACCACCGCCACGCCCGGCCCCTGGCACATCGAGCGCATGCTGCA
GGCGGCCGATGCGTTCCCGATGAACCTGGGCTTCCTCGGCAAGGGCAATGCGAGCCTGCCGGATGCGCTGCACGAGCAGA
TCGAGGCCGGCGTCATCGGCCTGAAGCTGCACGAGGACTGGGGCACCACGCCCGCGGCCATCAGCAATTGCCTCGATGTG
GCCGACGCCACCGACACGCAGGTGGCGATCCACAGCGACACGCTCAACGAATCGGGCTTTGTCGAGAACACCATCGCCGC
CGTGGGTGGCCGCGCGATCTGCGCGTTCCACACCGAAGGCGCGGGTGGCGGCCATGCACCGGACATCCTGCGCGTGGTGG
GCGAGGCGAACTTCCTGCCGTCGTCCACCAACCCCACGATGCCCTACACCGTGAACACGCTCGACGAGCACGTCGACATG
CTCATGGTGTGCCACCACCTCGATGCAGGAATCGCCGAAGACCTGGCCTTCGCCGAGTCGCGCATCCGCAAGGAAACCAT
CGCCGCCGAAGACGTGCTGCACGACCTCGGCGCAATCAGCATGTTCAGCTCCGACAGCCAGGCCATGGGCCGCGTCGGCG
AGGTGATCATCCGCACCTGGCAGACCGCGCACAAGATGAAGGTGCAGCGCGGCACGCTCCCCGAAGACAGCGAACGCAAC
GACAACTTCCGCGCGAAGCGCTACGTCGCCAAGTACACGATCAACCCGGCGATCGCGCACGGCATCGCGCACGAGGTGGG
CTCGCTGGAAGTCGGCAAGTGGGCCGACATCGTGATCTGGAAGCCCGCCTTCTTCGGCGTGAAGCCCTTCACCATCCTGA
AGGGCGGCACGATTGCGATGGCCGCGATGGGCGACCCGAGCGCGTCGATCCCGACGCCGCAGCCGGTGCACTTTCGCCCG
ATGTTCGGCGCGTACGGCGGCTCGCTCGCGAAGAGCTCGCTCACCTTCGTCTCGCAGGCCGGGCTCGCCTCGGGCATCAA
GGAGCGCTACGGTTTAGCCAAGCACCTCTGCGCGGTGAAGAACATCCGCAACGTGCGCAAAGGCGACCTGATCCACAACG
GCTATACGCCGAAGATGGAAATCGATGCGCAGACCTACGCGGTGCGCGCCGACGGGCATCTGCTGACCTGCGAGCCGGCG
AAGCTGCTGCCGATGGCGCAGCGGTATTTCCTGTTCTAG

Protein sequence :
MATIGRRAYAEIFGPTVGDRVRLADTELLIEVEADYTLRAGGYGEEVKFGGGKTIRDGMAQSQRTRAQGAVDTVLTNALI
LDHWGIVKADIGLKDGRIAAIGKAGNPDVQPGVDIVIGPGTEIISCEGNIVTAGGIDSHIHFICPQQIEEALSSGVTTML
GGGTGPATGTFATTATPGPWHIERMLQAADAFPMNLGFLGKGNASLPDALHEQIEAGVIGLKLHEDWGTTPAAISNCLDV
ADATDTQVAIHSDTLNESGFVENTIAAVGGRAICAFHTEGAGGGHAPDILRVVGEANFLPSSTNPTMPYTVNTLDEHVDM
LMVCHHLDAGIAEDLAFAESRIRKETIAAEDVLHDLGAISMFSSDSQAMGRVGEVIIRTWQTAHKMKVQRGTLPEDSERN
DNFRAKRYVAKYTINPAIAHGIAHEVGSLEVGKWADIVIWKPAFFGVKPFTILKGGTIAMAAMGDPSASIPTPQPVHFRP
MFGAYGGSLAKSSLTFVSQAGLASGIKERYGLAKHLCAVKNIRNVRKGDLIHNGYTPKMEIDAQTYAVRADGHLLTCEPA
KLLPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 9e-172 70
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 9e-172 70
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-150 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-150 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 6e-150 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-150 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Varpa_4858 YP_004157130.1 urease subunit alpha VFG0270 Protein 6e-142 60