Gene Information

Name : Varpa_4689 (Varpa_4689)
Accession : YP_004156963.1
Strain : Variovorax paradoxus EPS
Genome accession: NC_014931
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 5110623 - 5111930 bp
Length : 1308 bp
Strand : -
Note : KEGG: vap:Vapar_1926 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase

DNA sequence : 
ATGCAAGCAGCAGCCATTCATTCAAATCAACCGATCGCGATCATTGGCCTGGGCTACGTGGGCCTTCCTCTGGCCGTGGA
GTTCGGCAAGAAGCGCCAGGTGGTCGGCTTCGACATCAATGCCAAGCGAATTGCCGAGCTGCAAAACGGGCAAGACCACA
CGCTCGAAACCACGCCCGAAGAACTGAAGGCCGCTGCACAACTGGCCTTCACATCGCACCTCGACGACCTGCGCGACTGC
GGTGTCTTCATCGTGACCGTGCCCACGCCCATCGACAACGCCAACCGGCCCGACCTGACGCCGTTGATCAAGGCCAGCGA
ATCCGTCGGCAAGGTGATGAAGCCCGGTGCCATCGTGATCTTCGAATCGACGGTGTACCCGGGCGCGACGGAAGAGGTTT
GCGTACCCGTGCTGGAAAAATTCAGCGGCAAGAAGTTCAACGTCGACTTCTTCTGCGGGTACAGCCCGGAGCGGATCAAT
CCGGGGGACAAGGTCAACACGCTCACCAAGATCAAGAAGATCACCAGCGGAAGCACGCCCGAAGTGGCCGACCTGGTGGA
TGCGCTCTACAACGAGATCATTACCGCCGGCACGCACAAGGCCACCAGCCTCAAGGTGGCCGAGGCCGCGAAGGTGATCG
AGAACACGCAGCGCGACCTGAACATCGCGCTGGTCAATGAGCTCTCGGTGATCTTCGAACGCCTGGGCATCGACACCCTC
GACGTGCTGGAGGCCGCGGGCAGCAAATGGAATTTCCTGCCCTTCCGTCCGGGCCTCGTGGGCGGCCATTGCATCGGCGT
GGACCCCTACTACCTTACGCACAAGGCGGAGCAGGTCGGCTATCACCCGCAGGTGATATTGGCCGGCCGCCGCATCAACG
ACAACATGGCGCGCTACGTGGCCCGCAACACCATCAAGTTGATGTTGAAGAACGGCATGGACGTGCCGCGTTGCCGCATC
GGCGTGCTGGGCATCACCTTCAAGGAAAACTGCCCGGACATCCGCAACAGCAAGATCGTGGACATGGTGCGCGAGTTCGA
GGCATGGGGCGCTTCCGTGGAGGTTGTGGACCCGTGGGCGGAAGCTGAAGAAGTGGCTCGCGAGTACGGCCTTCAACTCG
GAAAGGTCGATGCAGACCACCCGGTCGATGCGCTGGTCGTTGCCGTGGGCCACAACGAATACCGCGGCGCGGCGATGTCC
GAGCTGCGCGCCCTGTGCCGAGGCGAGCAGCCCGTGCTGGTCGACGTCAAGAGCCTGTTCAACGCACAGGAAGCCCGCAA
CAGCGGCTTCTCCGTGTTCCGCCTGTAA

Protein sequence : 
MQAAAIHSNQPIAIIGLGYVGLPLAVEFGKKRQVVGFDINAKRIAELQNGQDHTLETTPEELKAAAQLAFTSHLDDLRDC
GVFIVTVPTPIDNANRPDLTPLIKASESVGKVMKPGAIVIFESTVYPGATEEVCVPVLEKFSGKKFNVDFFCGYSPERIN
PGDKVNTLTKIKKITSGSTPEVADLVDALYNEIITAGTHKATSLKVAEAAKVIENTQRDLNIALVNELSVIFERLGIDTL
DVLEAAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKAEQVGYHPQVILAGRRINDNMARYVARNTIKLMLKNGMDVPRCRI
GVLGITFKENCPDIRNSKIVDMVREFEAWGASVEVVDPWAEAEEVAREYGLQLGKVDADHPVDALVVAVGHNEYRGAAMS
ELRALCRGEQPVLVDVKSLFNAQEARNSGFSVFRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-123 62
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-123 62
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-112 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Varpa_4689 YP_004156963.1 nucleotide sugar dehydrogenase VFG0431 Protein 5e-124 62