Gene Information

Name : Varpa_3277 (Varpa_3277)
Accession : YP_004155573.1
Strain : Variovorax paradoxus EPS
Genome accession: NC_014931
Putative virulence/resistance : Virulence
Product : type VI secretion ATPase, clpv1 family
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3529484 - 3532189 bp
Length : 2706 bp
Strand : -
Note : TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp ATPase-like; KEGG: reh:H16_A0651 ATP-dependent protease Clp, ATPase subunit; SMART: AAA ATPase

DNA sequence :
ATGGCGATCTCCCGACGGGCGTTGTTCGGCAAGCTCAATCTCACCCTGTTTCGCGGCATTGAAGCCGCAACAGCATTTGC
CAAGCTGAGAGGAAATCCATATGTCGAATTGACGCACTGGATTCATCAAATCTGGCAAATCAATGACAGCGATTTGCATC
GCATCTGCCGCCATTACCAAATTGATTTTCAGGTTGTCGAAAAAGATCTGATTTCCAGATTGTCGGAATTGCCCTCGGGC
GCGACATCGCTGAGCGATTTTTCCCATCACGTCGAAACGGCCATCGAGCGCGCCTGGATTCTCTCCAGCCTCGAATTCGG
CGATCGTCGTGTGCGCAGTGCGTGGCTGCTTGCGGCGTTGGTGCAAACGCCAGATCTGCGGCGGCTGCTCCTTGGCGTAT
CGCCCGCCTTCCGAAAGCTCCCGGTCGAGCAGTTGATGGATGACGTCATTTCCCTCATCGCAGGCTCCCCGGAAGACAAC
GAAGGGTCGCACGATGGCTTGGGCCTCCCGGCCGCAATGCCAGGAGAAGCGAGCGGCGCGATCGCCGATTCGCCGGACGG
CAAATCCGCCCTGGCGCGGTATTGCCGAGACCTGACCGACAGCGCGCGCGGCGGCGAAATCGATCCGGTGATCGGCCGCG
AACACGAGATCCGCACGATGGTCGACATCCTGCTGCGCCGGCGGCAGAACAACCCTCTGCTCACCGGAGAGGCCGGGGTG
GGCAAGACAGCCGTGGTCGAAGGACTCGCGCTGGCAATCGCCAACGGCGAGGTTCCGCCCTCGCTGCGCGATGCTCGCCT
GCTCAGTCTCGATGTAGGTGCGTTGCTCGCTGGTGCCAGCATGCGGGGGGAGTTCGAGTCCCGTCTGAAGTCTCTGCTCG
AAGAAGCGAGCAAGTCGAGTCAGCCGGTCGTTCTTTTCATCGACGAGGTGCACACCCTGATCGGTGCCGGCGGACAGGCT
GGTACCGGAGATGCAGCCAATCTGCTCAAGCCTGCTCTCGCACGCGGCACCTTGCGCACCATCGGCGCGACCACGTGGAG
CGAATACAAGCGCCATATCGAGAAGGACCCTGCGTTGACCCGTCGTTTTCAGACGCTGCAGGTCGCCGAGCCGGAGGAGG
CCTCGGCCGTCGAAATGGTGCGCGGGCTGGTCGCCGTCTTTGCCGAACATCACGGTGTCACGGTGCTGGACGAGGCGGTG
CGGGCGGCGGTGTCCCTGTCCCATCGCTACATTCCGTCGCGCCAGTTGCCGGACAAGGCCATCAGCCTGCTCGACACGGC
CTGTGCACGTGTCGCCATGTCGCTGCACACGCCACCCGCCGTGGTCGATCAACTGCGCCAGCGAATCGCAGCCCTGGACG
TGGAACTCGCCTTGCTGGCTCAGGAAAGCGCGATCTCGCGGGGAAGTGATGCCCGATCAAAGCGCTTCGAAGCGGCAAAC
GCCCGACTCGATGCCACCGAACACGAACTGTCGACCTACGAGGCCCGGTGGCAAGAAGAGCTTGCGATGGTTCAGCAGAT
TCAATCGCTGAGAACAAAGAAGAGGGAGGAGAAGGGGGGGAGGGAGAGTGGCGCCGAGGGCGAGTGGCCCTCGGCGCGAC
TGCATGCTCTGGAAGAAGAGCTCCTGTTGCGCCAACAGGACTCGCCATTGGTTCTTTCTCAGGTCGACGAGTCGGTGATC
GCGGCCATCGTTGCGGATTGGACTGGGATACCCGTGGGCCGAATGGTGCAAGACGAAGTTGCCGCGGTCTTCAGGCTCGA
AGCCACTCTCGGCGAACGCGTCGTCGGCCAGGACCGCGCGCTTGCCGCGATTGCGGAGCGCATCCGTGTGTCGCGGGCGC
GGCTGACCGATCCGAACAAGCCGGTCGGCGTCTTCCTGCTGGCCGGTCCATCAGGCGTCGGAAAGACCGAAACCGCGTTG
GCACTTGCGGACGCCATGTATGGCGGCGAGCAGAACCTCATCACCATCAACATGAGCGAGTTCCTGGAGCCGCACACCGT
CTCGACACTGAAGGGCTCGCCGCCGGGCTACGTGGGCTACGGAGAAGGCGGTGTTCTGACGGAGGCCGTGCGCCGGAAGC
CCTACAGCGTGATCCTGCTCGACGAGGTGGAAAAGGCGCATCCGGACGTCCACGAAATCTTCTACCAGGTGTTCGACAAA
GGCTGGATGGAAGACGGTGAAGGCCGCCGCATCGACTTCAGAAACACCACCATCCTGTTGACGAGCAACGCAGGTGCGGA
ACTCATCGAGAGCCTGTGCGAAGACCCCGCATCGTCGCCCGAAGTCGAAACCCTGCGCGAAGCGCTCCAGCCTGTTCTTC
GCCAGGTTTTCCCGGCCGCATTCCTGGGGCGCCTGTCCGTCGTGCCTTATCTGCCATTGGGTGCGCAGGCCCTGGGTCGC
ATCGTCTCGCTGCATCTGGACCATGTGGTGCATCGGATGAAAAAGCAGCATGGCATCGAATTGCAATACGGCCCCGGCTT
GGTGGCCGAAATCGTCGATCGATGCGGCACGCATGAAACCGGGGCACGCCGACTGACGGGCTTCATCGAGCAGAACCTGC
TCCCGGTCTTGTCGCGGCAGTGGCTCAACGCCTTGCAGGAAAAGCGAACGATCGTCCGGATATCTGTCGACGCAAGGCCA
CTCGGGAAAACAGGGCCGCGTTCGCAGGAAGGAGATGTCGTCACCTGCCATACCGAGTACGTCTGA

Protein sequence :
MAISRRALFGKLNLTLFRGIEAATAFAKLRGNPYVELTHWIHQIWQINDSDLHRICRHYQIDFQVVEKDLISRLSELPSG
ATSLSDFSHHVETAIERAWILSSLEFGDRRVRSAWLLAALVQTPDLRRLLLGVSPAFRKLPVEQLMDDVISLIAGSPEDN
EGSHDGLGLPAAMPGEASGAIADSPDGKSALARYCRDLTDSARGGEIDPVIGREHEIRTMVDILLRRRQNNPLLTGEAGV
GKTAVVEGLALAIANGEVPPSLRDARLLSLDVGALLAGASMRGEFESRLKSLLEEASKSSQPVVLFIDEVHTLIGAGGQA
GTGDAANLLKPALARGTLRTIGATTWSEYKRHIEKDPALTRRFQTLQVAEPEEASAVEMVRGLVAVFAEHHGVTVLDEAV
RAAVSLSHRYIPSRQLPDKAISLLDTACARVAMSLHTPPAVVDQLRQRIAALDVELALLAQESAISRGSDARSKRFEAAN
ARLDATEHELSTYEARWQEELAMVQQIQSLRTKKREEKGGRESGAEGEWPSARLHALEEELLLRQQDSPLVLSQVDESVI
AAIVADWTGIPVGRMVQDEVAAVFRLEATLGERVVGQDRALAAIAERIRVSRARLTDPNKPVGVFLLAGPSGVGKTETAL
ALADAMYGGEQNLITINMSEFLEPHTVSTLKGSPPGYVGYGEGGVLTEAVRRKPYSVILLDEVEKAHPDVHEIFYQVFDK
GWMEDGEGRRIDFRNTTILLTSNAGAELIESLCEDPASSPEVETLREALQPVLRQVFPAAFLGRLSVVPYLPLGAQALGR
IVSLHLDHVVHRMKKQHGIELQYGPGLVAEIVDRCGTHETGARRLTGFIEQNLLPVLSRQWLNALQEKRTIVRISVDARP
LGKTGPRSQEGDVVTCHTEYV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 0.0 63
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-125 48
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 9e-126 48
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-96 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Varpa_3277 YP_004155573.1 type VI secretion ATPase, clpv1 family VFG2076 Protein 0.0 56
Varpa_3277 YP_004155573.1 type VI secretion ATPase, clpv1 family VFG2084 Protein 1e-131 45