Gene Information

Name : Varpa_2906 (Varpa_2906)
Accession : YP_004155208.1
Strain : Variovorax paradoxus EPS
Genome accession: NC_014931
Putative virulence/resistance : Virulence
Product : type VI secretion ATPase, clpv1 family
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3126436 - 3129174 bp
Length : 2739 bp
Strand : +
Note : TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; KEGG: vap:Vapar_0200 type VI secretion ATPase, ClpV1 family; SMART: AAA ATPase

DNA sequence :
ATGACCGACATCCGCCGCGTCTCTCTCTTTTCCAAGCTGAACCCGATGCTCTACAAGGCATTGGAGACCGCCACCGCCTT
CGCCAAGCTGCGCGGCAACGCCTACGTCGAACTCGTGCACTGGCTGCACCAGATCCTGCAGCTGCAGGACAGCGACATGC
TGCGCATCGTCAAGCGGGCGGGGCTCAACCTCGATGCGGTGGAGCAGGACCTCGTGCGCGCGCTCGACCGCCTGCCGCAT
GGCGCGACGTCGATCAGCGACATCTCCGAGCACGTGGACAACGCCGTCGAACGCGCGTGGGTGTATGCGAGCCTGCGCTT
CGAGGCCACGTCGATTCGCGGCGGGTATCTTCTGGCCGGCATCACCAAGACGCCGGGGTTGCGCCAGGTCCTCTCGGGCA
TCTCGCGCGAGTTCGACAAGATCGTGCCCGACGTTTTGGTGGCCCAACTCGAGGCGTGGACCGAAGGCTCGCCAGAAGAC
GACTACGACATCACGCCGAACGAGGGCGCGGGCGGCGGTGCGCCGGCCATGCAACACCAGGGCGATGGAACGCCGGCAGG
CGGCTCTGCGCTCGCGAAGTACGCGAGCGACCTCACGGCCAAGGCGCGTGCGGGCGAACTCGATCCGGTCTACGGCCGCG
ACGAGGAGATCCGCCAGATCATCGACATCCTCATGCGCCGCCGGCAGAACAACCCGCTGCTCACCGGCGAGGCCGGCGTG
GGGAAGACGGCGGTGGTTGAAGGCCTGGCCTCGCGGCTGGCTTCGGGCGATGTGCCGCCTTCGCTCAAGGACGTGTCGCT
CTGGGTGCTCGACCCCACGCTGCTGCAGGCCGGCGCGGGCGTGAAGGGCGAGTTCGAGCAGCGGCTGCGCCAGGTGATCG
ACGAGGTCGAGAAAAGCCCCAAGCCCATCGTGCTCTTCGTCGACGAGGTGCACACGCTGGTCGGCGCGGGCGGCACGGCC
GGCACCGGCGATGCGGCCAACCTGCTCAAGCCCGCGCTCGCGCGCGGCCGGCTTCGCACCATCGGCGCAACGACGTGGTC
GGAGTACAAGAAGTACATCGAGAAAGACCCGGCGCTCACGCGGCGTTTCCAGACCATCCAGGTGCATGAGCCCACCGAGC
CCAAGGCGGTGATCATGCTGCGCGGCATTTCGGCGGAACTGGAGAAGCACCACGGCGTGCTGATCCTCGATGCGGCGCTT
GAAGCGGCCGTGAGCCTGTCGCACCGCTACATTCCCGCGCGGCAGTTGCCCGACAAGGCCGTGAGCCTGCTCGACACGGC
GTGCGCGCGTGTGGCACTGAGCCAGCATGCGCTTCCGGCGGCGCTCGAAGACCTGCAACGGCGCATCGAGGTGCTCGGCA
TCGAGTCCGGCATCGCGGGGCGCGAAGCCGCGATCGGCGTCGGAGAGCACCAGCGTGTCGAGGACATCGCGGCCCAGGTG
GCCGCCGCGCAAGCCGAACTCGATCTGCTGGAGCAGCGGCGGCTGGAAGAGAGCGCGCTGGTCGAGCGCATCGTGGCGCT
GCGCAAGCTGTTGTCGCCCGCGGCGGTGCCGGTGCAGGCCGAAGCCGACGTCGAAGTTGAAACCGAAGAGGACGCCGACC
CGGTCGGCGAAGCACCGCAAGTCGATGCGGAGCCCGAACGCACCCCTGAAGACATTCGCGCCGAACTCAACGAAGCGCAG
GACAAGCTGGTGCAGCTGCAGGGCGAATCGCCGCTGATCCTCGCCGCCGTCGATGCGCAGGCCATCGCCACCGTCGTGGC
CGACTGGACCGGCATTCCCATCGGCCGCATGGTGCGCGACGATGCGCAGTCCGTGCTGCGCCTGGGCGAGATCCTCTCGG
CCCGCGTGGTGGCCCAGCCCGATGCGCTGGAGACCATCTCGCGGCGCATCCGCACAGCGCGCGCGCGGCTGGACAACCCC
AACAAGCCCGTCGGCGTTTTCCTGCTGTGCGGCCCCTCGGGCGTCGGCAAGACGGAGACCGCGCTCGCGCTTTCGGAAGC
GTTGTATGGCGGCGAGCAGAACCTCGTGACCATCAACATGAGCGAGTTCCAGGAGTCGCACACGGTCTCCACGCTCAAAG
GCGCGCCGCCCGGCTACGTGGGCTATGGCGAAGGCGGCGTGCTCACCGAAGCCGTGCGCCGCCGGCCCTACAGCGTGGTG
CTGCTCGACGAGATCGAGAAGGCGCACACCGATGTGCACGAGATCTTTTTCCAGGTGTTCGACAAGGGCTGGATGGAAGA
CGGAGAAGGACGCCACATCGACTTTCGCAACACCGTGATCATCATGACCTCCAACGTCGGCACCGACCTGGTCATGCAGT
TGTGCGAAGACCCGACCCTGCGCCCCGACCCCGAACCGCTTGCAGCGGCGCTGCGCGAACCGCTGCTCAAGGTGTTTGCG
CCGGCGCTGCTCGGGCGGCTGGTTGTAGTGCCTTATTACCCGTTGCAGGCCGATGCGTTGCATCGCATCATCCGCCTTCA
GCTCGACCGCATCGCGGCGCGGCTCGACGCCAACCACGGCATCGCCATGCACTACGACGACAGCGCCGTGGAACTGGTGG
CGCGCCGCTGCACGGCCATCGAGTCGGGCGGCCGGATGATCGACGCCATCCTCACGCACACCATCCTCCCCCGGCTGAGC
GAAGAGGTCATCGGCGCCACCGTCGGCGCGCGCAAGCTCGCGGGCGTGCGGCTGTCGGCACAGGAAGACGACTTCCGATA
CGAATTCTCGGAAGCATAA

Protein sequence :
MTDIRRVSLFSKLNPMLYKALETATAFAKLRGNAYVELVHWLHQILQLQDSDMLRIVKRAGLNLDAVEQDLVRALDRLPH
GATSISDISEHVDNAVERAWVYASLRFEATSIRGGYLLAGITKTPGLRQVLSGISREFDKIVPDVLVAQLEAWTEGSPED
DYDITPNEGAGGGAPAMQHQGDGTPAGGSALAKYASDLTAKARAGELDPVYGRDEEIRQIIDILMRRRQNNPLLTGEAGV
GKTAVVEGLASRLASGDVPPSLKDVSLWVLDPTLLQAGAGVKGEFEQRLRQVIDEVEKSPKPIVLFVDEVHTLVGAGGTA
GTGDAANLLKPALARGRLRTIGATTWSEYKKYIEKDPALTRRFQTIQVHEPTEPKAVIMLRGISAELEKHHGVLILDAAL
EAAVSLSHRYIPARQLPDKAVSLLDTACARVALSQHALPAALEDLQRRIEVLGIESGIAGREAAIGVGEHQRVEDIAAQV
AAAQAELDLLEQRRLEESALVERIVALRKLLSPAAVPVQAEADVEVETEEDADPVGEAPQVDAEPERTPEDIRAELNEAQ
DKLVQLQGESPLILAAVDAQAIATVVADWTGIPIGRMVRDDAQSVLRLGEILSARVVAQPDALETISRRIRTARARLDNP
NKPVGVFLLCGPSGVGKTETALALSEALYGGEQNLVTINMSEFQESHTVSTLKGAPPGYVGYGEGGVLTEAVRRRPYSVV
LLDEIEKAHTDVHEIFFQVFDKGWMEDGEGRHIDFRNTVIIMTSNVGTDLVMQLCEDPTLRPDPEPLAAALREPLLKVFA
PALLGRLVVVPYYPLQADALHRIIRLQLDRIAARLDANHGIAMHYDDSAVELVARRCTAIESGGRMIDAILTHTILPRLS
EEVIGATVGARKLAGVRLSAQEDDFRYEFSEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-121 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-121 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Varpa_2906 YP_004155208.1 type VI secretion ATPase, clpv1 family VFG2076 Protein 0.0 59
Varpa_2906 YP_004155208.1 type VI secretion ATPase, clpv1 family VFG2084 Protein 3e-127 41