Gene Information

Name : Varpa_2722 (Varpa_2722)
Accession : YP_004155031.1
Strain : Variovorax paradoxus EPS
Genome accession: NC_014931
Putative virulence/resistance : Unknown
Product : integrase family protein
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 2933381 - 2934592 bp
Length : 1212 bp
Strand : +
Note : PFAM: integrase family protein; KEGG: rfr:Rfer_1354 phage integrase

DNA sequence :
ATGGCATTGACGGATATGGCAGCACGCAAGGCAAAGCCTGAGGTTCGCTCATACAACCTCACGGACGGGGCGGGCCTATA
TCTGCAGGTGACGCCTGCAGGCGGCAAACTGTGGCGCTGGAACTACCGCCATGATGGCAAGCAGAAGACGATGGCCTTCG
GGAGCTACCCCGAGGTGTCGATCGCTGACGCACGCGAAGCACACCAGGCGGCGCGCAAGCAGAAGGCCGCGGGCGCTGAT
CCAATGGCGCAGCGGAAGCTGGACAAGATCGCAGGGGTGATGGCTAGGGAGCACTCATTCAAGGCCATTGCACAACAGTG
GCACGACCAGTGGAAGCCGAACAAGGCCGAGCGGCATGCTCGCATTGTGTGGGGCCGCCTTGAGAACGATGTCTTCCCTG
CTATCGGTGCGCGACCGATCTCCGAGGTCAAACCTTCGGAGCTCGTGGCCATGATCAAGAAGATAGCCGGCCGCGGCGCA
CCTGACATGGCGAAGCGGTGCCTGGAGATCAGTGGGCAGGTCTTTCGTTATGCCGTGGCGCATGGCATTTCCGAGCGAAA
CCCGGCTGCGGACATCAAACCTGGCGACGTGTTGCCGCCGCGAAAGACGAACCACTTCGCGCGCGTCGAATCGAGTGAGC
TGCCAGACCTACTTCGCAAGATCGAAGCCTACTCAGGGACGCCTGCTACGCGGCTGGCGATGAAGCTGATGGCCTATACC
TTTGTGCGCACGGGTGAGCTCATCGGCGCGCGTTGGCCCGAGTTCGACCTCGATGCCGCTGTGTGGCGCATCCCTCCAGA
GCGTATGAAGATGAAGACGCTGCACATCGTCCCGCTGTCGACGCAGGCTGTCGAGGTGCTGCGCACGCTCCAACTGGTGA
CCGGGGACAGTGCGCTGCTCTTTCCTGGTGAGAGAGATCATGAGAAGTCGATCAGCAACAATACCATCCTGGGCGCGCTG
AAGCGGATGGGCTACGCGGGTCGAATGACCGGCCACGGCTTCCGCGGTGTGGCCTCGACCGAATTGCACGAGATGGGGTT
CGAGGAGGCGCACATCGAGGCGCAGATGTCGCACCTGAAGCGCAACCGAGTCGCCTCGGCCTACGACCATTCGAAGTACC
TCAAGCAGCGCGTCGCGATGATGCAGACTTGGGCCGATCGTCTCGACCAGTTCCGCGCTGGCGCGAAGATCTTGCCGTTC
AAGGCTGCGTAG

Protein sequence :
MALTDMAARKAKPEVRSYNLTDGAGLYLQVTPAGGKLWRWNYRHDGKQKTMAFGSYPEVSIADAREAHQAARKQKAAGAD
PMAQRKLDKIAGVMAREHSFKAIAQQWHDQWKPNKAERHARIVWGRLENDVFPAIGARPISEVKPSELVAMIKKIAGRGA
PDMAKRCLEISGQVFRYAVAHGISERNPAADIKPGDVLPPRKTNHFARVESSELPDLLRKIEAYSGTPATRLAMKLMAYT
FVRTGELIGARWPEFDLDAAVWRIPPERMKMKTLHIVPLSTQAVEVLRTLQLVTGDSALLFPGERDHEKSISNNTILGAL
KRMGYAGRMTGHGFRGVASTELHEMGFEEAHIEAQMSHLKRNRVASAYDHSKYLKQRVAMMQTWADRLDQFRAGAKILPF
KAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 3e-77 44
int AAD44730.1 Int Not tested SHI-2 Protein 1e-74 43
int AAC31482.1 CP4-like integrase Not tested LEE Protein 3e-74 42
int ACU09430.1 integrase Not tested LEE Protein 3e-74 42
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 4e-74 42
ECs4534 NP_312561.1 integrase Not tested LEE Protein 4e-74 42
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-75 42
int CAC39282.1 integrase Not tested LPA Protein 4e-75 42
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 2e-64 41
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 2e-64 41
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 6e-64 41
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 1e-63 41
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 8e-64 41
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 6e-64 41
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 4e-63 41
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 2e-62 41
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 2e-62 41
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 1e-62 41
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-64 41
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 4e-63 41
int AAL51028.1 CP4-like integrase Not tested LEE Protein 4e-63 41
int-phe AAL60261.1 Int-phe Not tested LEE Protein 4e-63 41
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 3e-63 41
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 5e-63 41
int AAL51003.1 CP4-like integrase Not tested LEE Protein 2e-63 41
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 5e-63 41
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 3e-64 41
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-64 41
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 2e-62 41
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 3e-77 41
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 4e-68 41
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 4e-68 41
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 3e-73 41
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 4e-73 41
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 4e-73 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Varpa_2722 YP_004155031.1 integrase family protein VFG0783 Protein 2e-74 42
Varpa_2722 YP_004155031.1 integrase family protein VFG0626 Protein 7e-65 41
Varpa_2722 YP_004155031.1 integrase family protein VFG1693 Protein 2e-64 41
Varpa_2722 YP_004155031.1 integrase family protein VFG0598 Protein 2e-73 41