Gene Information

Name : Theam_0601 (Theam_0601)
Accession : YP_004151214.1
Strain : Thermovibrio ammonificans HB-1
Genome accession: NC_014926
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 551955 - 553268 bp
Length : 1314 bp
Strand : +
Note : KEGG: sul:SYO3AOP1_1757 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase

DNA sequence :
ATGGTTGAGTTTCCTACTTTTGAAGATTTCCTCTCGGGAAGGGAAAAGGTTGCGGTTGTAGGCTTAGGTTACGTGGGTCT
TCCCTTGGCGGTTCTCCTGGGTAGAAAGTTTAAAGTTGTCGGTTTTGACGTAAACCCGGAGAGGGTTGCGCAGCTGAAGG
CCGGCATCGATAAAACCGGTGAGGTTTCCCGCGAGGCCATAGAGGAGGCCTCGGTAGAGTTTACAACCGAGCCGGAGGAG
CTTTCAGGGTGCCGCCTCATTATCGTTACCGTTCCGACTCCCGTGGATAGGCACAACATACCCGATTTAAGACCTGTGAA
ACTTGCAACGAAAACAGTTGGCAGACACATGGTTCCCGGGACGGTGGTTGTTTACGAATCTACGGTTTACCCGGGTCTTA
CCGAGGAGGTGTGCGTTCCGCTCCTGGAGAAGGAGTCGGGGCTGAAGTACATGGAAGAGTTTAAAGTTGGCTACTCCCCG
GAGAGAGTTAATCCCGGAGATAAAAAACACACCATAGAGAAAATAGTTAAGGTGGTTGCCGGCTGCGACGACGAAACGGC
AGACCTCCTTGAAAAGGTTTACGGTTCCGTTATAGAGGCGGGCGTTTACAGGGCTCCCAACATTAAAACTGCAGAGGCCG
CAAAGGTTATAGAGAACACCCAAAGGGACTTAAACATAGCCCTTATGAACGAACTCGCCCTCATATTCCACAGAATGGGA
ATAGATACTCGAGACGTTATAGAGGCGGCGGCTACCAAGTGGAACTTCCTGAAATTTGAGCCGGGCCTTGTGGGAGGGCA
CTGTATAGGCGTTGACCCCTACTACCTTACCTTTAAGGCCCAGGAGCTCGGCTATCACCCCGAAGTTATTCTTGCCGGCA
GGCGGATTAACGACTACATGGGTAAGTTTGTTGCCGAACAGACCGTTAAGCAGATGATAAAAGCCGGTAAGCAGGTTCTT
AACGCCAAAGTTCTGGTTATGGGCGTAACGTTTAAGGAGAACGTGAAGGATGTAAGGAACAGTAAGGTTATAGATATCTA
TAACGAGCTCAACTCCTACGGTGTGAAGGCTTTCCTTTACGACCCCGTTGCCGACGGAGAGGAGTTTAAGCGGGAGTACG
GCGTTGAGCTTATAGAGTCGGTGGAGGCGGAAGCTCCTTACGACGCCGTTGTTGTTGCGGTTAAGCACGACAGCTTTAAA
GAGCTTCCCCCCGAGTTCTTCCGCTCCATTCTCGGGGAGCCTCCGATACTCATAGACGTAAAGGGCATTTACAACAGGGA
GCGGTTTAAGGATTTCCTTCTGTGGAGACTCTAA

Protein sequence :
MVEFPTFEDFLSGREKVAVVGLGYVGLPLAVLLGRKFKVVGFDVNPERVAQLKAGIDKTGEVSREAIEEASVEFTTEPEE
LSGCRLIIVTVPTPVDRHNIPDLRPVKLATKTVGRHMVPGTVVVYESTVYPGLTEEVCVPLLEKESGLKYMEEFKVGYSP
ERVNPGDKKHTIEKIVKVVAGCDDETADLLEKVYGSVIEAGVYRAPNIKTAEAAKVIENTQRDLNIALMNELALIFHRMG
IDTRDVIEAAATKWNFLKFEPGLVGGHCIGVDPYYLTFKAQELGYHPEVILAGRRINDYMGKFVAEQTVKQMIKAGKQVL
NAKVLVMGVTFKENVKDVRNSKVIDIYNELNSYGVKAFLYDPVADGEEFKREYGVELIESVEAEAPYDAVVVAVKHDSFK
ELPPEFFRSILGEPPILIDVKGIYNRERFKDFLLWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 5e-104 54
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-102 54
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-102 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theam_0601 YP_004151214.1 nucleotide sugar dehydrogenase VFG0431 Protein 3e-102 54