Gene Information

Name : Mesci_4442 (Mesci_4442)
Accession : YP_004143602.1
Strain : Mesorhizobium ciceri WSM1271
Genome accession: NC_014923
Putative virulence/resistance : Resistance
Product : aminoglycoside/hydroxyurea antibiotic resistance kinase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG3570
EC number : -
Position : 4571017 - 4571856 bp
Length : 840 bp
Strand : +
Note : PFAM: aminoglycoside/hydroxyurea antibiotic resistance kinase; KEGG: mlo:mll8451 streptomycin phosphotransferase, streptomycin-resistance

DNA sequence : 
ATGGACACGCCAGCCTTTCCGGCGCGCTGGAAAGTCAGCGCGCCCGAACTCATTGCCGAGACCTTTTCGAGCCGCATCTG
GAAGGTATTGCGCGAAGACGGATCGCCGGCGATCGTCAAGGCGCTGAAGCCTTTCGATGACGTCGCCGACGAGTTGCGCG
GAGAGCACTATCTCGCCTGGCGGCGCGGCGAAGGCGCGGTGCGTCTGCTCGGCCGCGACGGCCACAGCATGCTGCTCGAA
TATGCCGGTGAAACCCTGCTGCAGCAGGTTCTCGACGAACAGGGCGACTTTGCCGCGACCGCAATCGCGGCGGAGCTGAT
GGCAAAACTGTTTTCACGGGGGAAAGCCCCCTACCCGTCCGAGCTTCAGCCGCTCCGGGAACGCTTCGCCAGCCTGTTCG
ACAAGGCGAATACCGATCGCGACGCCGGCCTTGACAGCCTCTATGTCGAGGCAGCCGTCATCGCCGAGCGGCTGCTGGCC
GATCCGCACGACATCAGGCCCCTGCATGGCGATCTGCATCACGAAAACATCCTGCACGGGCCGCGCGGCTGGCTGGCGAT
CGATCCGAAGGGCGTGCTCGGCGATCCCGGCTTCGACGCGGCGAACATGTTCTACAACCCGCTCGACCGGGACGATCTCT
GCCTCGATCCGGAGCGGATCGCTGATATGGCCGAGATCTTTGCCAAAACACTGAGCCAGACACCGACCGCTATCCTCGAT
CATGCCATTGCCTATGGATGCCTGTCGGCGTCCTGGCATCACGAGGACGACAATGCGGTCGAGGAGAATCGCGAAATGTC
GATCGTCAAGGCGATCCGGGCGGTGCGGGCAGGCTTCTGA

Protein sequence : 
MDTPAFPARWKVSAPELIAETFSSRIWKVLREDGSPAIVKALKPFDDVADELRGEHYLAWRRGEGAVRLLGRDGHSMLLE
YAGETLLQQVLDEQGDFAATAIAAELMAKLFSRGKAPYPSELQPLRERFASLFDKANTDRDAGLDSLYVEAAVIAERLLA
DPHDIRPLHGDLHHENILHGPRGWLAIDPKGVLGDPGFDAANMFYNPLDRDDLCLDPERIADMAEIFAKTLSQTPTAILD
HAIAYGCLSASWHHEDDNAVEENREMSIVKAIRAVRAGF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
strB AEA34676.1 aminoglycoside resistance protein B Not tested Not named Protein 8e-82 58
BJAB07104_00281 YP_008207746.1 Streptomycin 6-kinase Not tested AbaR25 Protein 1e-81 58
BJAB0868_00285 YP_008211611.1 Streptomycin 6-kinase Not tested AbaR26 Protein 1e-81 58
strB YP_001800933.1 aminoglycoside-6-phosphotransferase Not tested Not named Protein 1e-81 58
strB AFV47971.1 streptomycin (6) phosphotransferase StrB Not tested AbaR25 Protein 7e-82 58
ABZJ_00265 YP_005524221.1 streptomycin 3''-kinase Not tested AbaR22 Protein 9e-82 58
strB AFV47999.1 streptomycin (6) phosphotransferase StrB Not tested delta-AbaR25 Protein 7e-82 58
strB YP_005176179.1 aminoglycoside 6-phosphotransferase protein Not tested ICEPmu1 Protein 9e-82 58
strB AEQ20908.1 StrB, APH(6)-Id streptomycin(6) phosphtransferase Not tested Tn6166 Protein 9e-82 58
strB AEZ06048.1 StrB, APH(6)-Id, streptomycin(6) phosphotransferase Not tested Tn6167 Protein 9e-82 58
strB ACK44538.1 StrB Not tested SGI1 Protein 7e-82 58
strB AGK07030.1 StrB streptomycin phosphotransferase Not tested SGI1 Protein 7e-82 58
strB AGK07088.1 StrB streptomycin phosphotransferase Not tested SGI1 Protein 7e-82 58
ABK1_0257 YP_005512829.1 Streptomycin resistance protein B Not tested AbaR4d Protein 9e-82 58
strB AFH57206.1 streptomycin resistance protein Not tested AbaR4a Protein 7e-82 58
strB CAJ77026.1 Streptomycin phosphotransferase B Not tested AbaR1 Protein 2e-82 58

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesci_4442 YP_004143602.1 aminoglycoside/hydroxyurea antibiotic resistance kinase NC_010410.6003392.p0 Protein 1e-82 58
Mesci_4442 YP_004143602.1 aminoglycoside/hydroxyurea antibiotic resistance kinase DQ464881.1.gene5.p01 Protein 4e-82 58
Mesci_4442 YP_004143602.1 aminoglycoside/hydroxyurea antibiotic resistance kinase AF024602.1.gene6.p01 Protein 5e-82 57
Mesci_4442 YP_004143602.1 aminoglycoside/hydroxyurea antibiotic resistance kinase AJ313522.gene.p01 Protein 2e-70 53