Gene Information

Name : Mesci_3448 (Mesci_3448)
Accession : YP_004142621.1
Strain : Mesorhizobium ciceri WSM1271
Genome accession: NC_014923
Putative virulence/resistance : Resistance
Product : Bcr/CflA subfamily drug resistance transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 3602466 - 3603662 bp
Length : 1197 bp
Strand : -
Note : KEGG: mxa:MXAN_2566 drug resistance transporter Bcr/CflA family protein; TIGRFAM: drug resistance transporter Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1

DNA sequence :
ATGCCTTTTCCAAAAAACCCGACATGGACCACTTCCCTGCCAGCAGCCATGGTGCTGATGGCGCCCTTCGACATCCTGGC
CTCGCTGGCCATGGACATCTACCTCCCGATTGTCCCGGCGATGCCGGGGATCCTCGAGACATCGCCTGATGTCATCCAGC
TGACGCTGAGCCTCTACATGATCTGTCTTGGGCTCGGCCAAGTCGTCTTCGGCCCGATTTCCGACAGGATCGGCAGGCGC
CCGGTGCTGATCGGTGGCGCGCTTTTGTTTTCAGGCGCTTCCTTTCTGCTCGCCAGCACCTCGCTGGCCGCTGTCTTCGT
CGTCCTGCGCGTCGTGCAGGCCATTGGTGCGTCCGCCATTCTCGTTGCAACCTTCGCAACGGTTCGCGACGTCTATGCGC
AAAGAGCCGAAAGTGCCGTCATTTACGGCCTGTTCAGCTCGATGTTGGCTTTCGTGCCGGCGTTGGGGCCGGTTGCCGGT
GCGTTGATTGCCGACAATTTCGGCTGGCGGGCGATCTTCCTGACGCTCGGAGTCCTGGCCACGGCAGCTACCCTCAACGC
ATGGCCGAAATGGCACGAAACCCGCCCCTCGAATGGCGATACCAGGCGAATGGCGCTTCGACCCATTCTCTCCAGTCTTG
CCTTCTGGACCTACACGCTTGCATTCAGTGCCGCCATGGGCGCCTTCTTCGTGTTCTTTTCGACTGCGCCACGGGTGCTC
ATGGATCGCGCCGGCTTTTCACAGTTCGGCTTCAGTCTAGCCTTCGCCACCGCGGCGCTGGTGATGATCGTCACCACCCG
CTTCGCCAGAAGGTTCATTGCAAGCTGGGGCATCGCCGGCAGTGCCATCAGGGGCATGGCGATGCTGCTGTTCGGCGCGG
CGCTATTGGCAGTGGGGCAACTGTTCGCACAGCCGTCCTTCGCGACATTTATCTTGCCGATGTGGGTCGTTGCCGTGGGT
ATCGTCTTCATTGTCTCAGTCACCGCAAACGGTGCACTCGAGGCGTTTGGCGATGTCGCGGGAACCGCAGTCGCACTCTA
CTTCTGCATCCAGAGCCTTGTCGTCGGCATCTTCGGCACGTTGTTCGTCGTCCTGCTCGGCGGAGACACGGCGTGGCCGC
TGGTCGCCTACTGTTCGGTCATGGCGACGCTCACACTAAGCGCACTGAGGCATTTGCAGAAACGCCAAACCGAATAG

Protein sequence :
MPFPKNPTWTTSLPAAMVLMAPFDILASLAMDIYLPIVPAMPGILETSPDVIQLTLSLYMICLGLGQVVFGPISDRIGRR
PVLIGGALLFSGASFLLASTSLAAVFVVLRVVQAIGASAILVATFATVRDVYAQRAESAVIYGLFSSMLAFVPALGPVAG
ALIADNFGWRAIFLTLGVLATAATLNAWPKWHETRPSNGDTRRMALRPILSSLAFWTYTLAFSAAMGAFFVFFSTAPRVL
MDRAGFSQFGFSLAFATAALVMIVTTRFARRFIASWGIAGSAIRGMAMLLFGAALLAVGQLFAQPSFATFILPMWVVAVG
IVFIVSVTANGALEAFGDVAGTAVALYFCIQSLVVGIFGTLFVVLLGGDTAWPLVAYCSVMATLTLSALRHLQKRQTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 5e-93 67
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 3e-96 66
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 3e-96 66
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 3e-96 66
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 2e-97 66
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 2e-97 66
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 3e-69 51
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 3e-69 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesci_3448 YP_004142621.1 Bcr/CflA subfamily drug resistance transporter AF156486.gene.p01 Protein 2e-68 52
Mesci_3448 YP_004142621.1 Bcr/CflA subfamily drug resistance transporter AF294653.1.gene4.p01 Protein 2e-69 51
Mesci_3448 YP_004142621.1 Bcr/CflA subfamily drug resistance transporter DQ984668.gene.p01 Protein 2e-69 51
Mesci_3448 YP_004142621.1 Bcr/CflA subfamily drug resistance transporter DQ522237.1.gene4.p01 Protein 2e-69 51
Mesci_3448 YP_004142621.1 Bcr/CflA subfamily drug resistance transporter NC_010410.6003586.p0 Protein 2e-69 51