Gene Information

Name : Mesci_2311 (Mesci_2311)
Accession : YP_004141509.1
Strain : Mesorhizobium ciceri WSM1271
Genome accession: NC_014923
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2410667 - 2412880 bp
Length : 2214 bp
Strand : +
Note : KEGG: mlo:mll2475 metal-transporting P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy me

DNA sequence :
ATGACGGCGCCCCTCGACCAGGTAAAAATCAGGCAGACGCGGTTCAAGATCGGCGGCATGGATTGCGCCTCTTGCGCAAC
CAAGATCGATACGGCGGTGCGTCGCCTAGACGGCGTCGCCGATGTCTCGGTTTCGGTGACCGGTGCCAGCATGACGGTCA
GCCATGGCGGCGCGTTGCCGGAAGGCAGGGTGCTGCAGCAGGTTGCTCGGCTCGGCTACGGCATCGTCAGGGCCGAGGCA
CATGTATCGCCGATGTCAGACAAGGCGCACGCCGATCACGTCCACAATGACCATGAAGGCCACGATCATGCGAGCCACGA
TCCCAATCCCGATCATGGCCATTCCGAGACGGGGCAGGCGTGGTGGCGTTCCCGCCGGGCGGTGCTGACGCTCGCCTGCG
CGGCAGCGCTTCTCGCCGCATACGGCATCGGCCATCTGTTCCCGGTGGCGGAACGCGGGGTGTTCCTGGCCGCGCTGTTG
GTCGGCCTGGTGCCGATCGCACGGCGCGCGCTGATGGCGGCATTGGCCGGCACGCCGTTTTCGATCGAGATGCTGATGAC
CATCGCGGCGATAGGCGCCGTGATGATCGGTGCCACTGAAGAGGCCGCCGCCGTGGTGGTGCTCTTCCTGATCGGCGAGC
TTCTGGAGGGTGTCGCCGCCGGCCGGGCGCGGGCGAGCATCCAGGGACTTGCCGATCTGGTGCCGAAGACGGCCTTGGTC
GAGCGCGCAGGCGGCACATCGGAGTGTCCCGCCGAAGACCTTGCGGTCGGCGACATCATCCTGGTGCGGCCGGGCGACCG
CATCCCGGCCGATGGCGAGATCATCGAGGGCGCGAGCGAAATCGACGAGGCGCCGGTGACCGGCGAGAGCACCCCGAAGC
GCAAGGGCGCTACGGACGCCGTCTTTGCCGGCACGATCAGCACCGATGGCGTGCTCAAGGTGCGGGTGACGGCGGCCGCT
TCCGACAACACCATCGCCCGAATCGCGCGGCTGGTGGAGGAGGCGCAGGAGGCCAAGGCGCCGACAGAGCGCTTCATCGA
TCGCTTCTCGCGCACCTACACGCCGGCGGTGCTGGCGGTCGGTGCGCTGGTGGCATTGTTGCCGCCGCTGCTTGCCGGCG
GCGACTGGAACGAATGGATCTACAAGGGCTTGGCGATCCTGCTGATCGGCTGCCCCTGCGCGTTGGTCATCTCGACCCCG
GCGGCAATCGCCGCGGGCCTTGCGACCGGTGCGCGGCGTGGCCTGTTGATGAAAGGCGGTGCGGTGCTGGAAGGCTTTCG
CCGGATCACGGCGGTCGCCTTCGACAAGACCGGTACGCTGACCGCAGGCAAGCCTGCCGTCACCGACATCGTGGCGTATG
GAAGGGATGAACGCACCGTGCTGGCGCTGGCGGCAGCACTGGAGCAGGGCTCCAGCCATCCGTTGGCGATGGCGATCCTG
GACCGGGCCAAGGCCGACAAGGCGCCGGTGCCGCCGGCTCTCGCGGCGAAGGCAATCTCGGGCAAGGGTGTCGAGGGCAG
CGTTGGCGGCGTCGCCGTCTTCCTCGGCTCCGGCCAGGCGGCGGGCGAACGCGCCGACATGACGCAAGCGCAGCGCCTCG
CCGTCGACAGCCTCAACGGCCAGGGCAAGACGGTGTCAGTGCTGGTCGCCGATGGCGTGGTGGCCGGGCTGATTGCCATG
CGCGACGAGCCGCGGCCGGATGCTGCGGCCGGGATCGCGGCGCTGGAGGCCGAGAGCATCCGCGCGGTGATGTTGACCGG
CGACAACCGCCGCACGGCGCAAGCCATCGCCGCTTCGCTCGGCATCGAGGCGCGGGCGGAGCTGTTGCCCCAGGACAAGC
AGCGCATCGTCGGCGAATTGCAGCGCGAGGGTTTCAAGGTCGCCAAGGTCGGTGACGGCATCAACGACGCGCCGGCGCTC
GCGGCCGCCGACATTGGCATTGCCATGGGCGGCGGCACCGACGTGGCGCTGGAGACCGCGGACGCGGCGATCCTGCACGG
CCGCGTCATGGACGTCGCGCGTATGGTGAAACTGTCGCGGGCGGTGATGGCCAATATCGGCCAGAACATCACCGTGGCGC
TGGGGCTGAAGGCGGTGTTCTTGGTCACCACCATTTTGGGCATCACCGGCCTGTGGCCGGCGATCCTGGCCGATACCGGC
GCGACCGTGCTGGTCACCGCCAACGCCATGCGCCTGCTGCGCTGGCGCGGGTGA

Protein sequence :
MTAPLDQVKIRQTRFKIGGMDCASCATKIDTAVRRLDGVADVSVSVTGASMTVSHGGALPEGRVLQQVARLGYGIVRAEA
HVSPMSDKAHADHVHNDHEGHDHASHDPNPDHGHSETGQAWWRSRRAVLTLACAAALLAAYGIGHLFPVAERGVFLAALL
VGLVPIARRALMAALAGTPFSIEMLMTIAAIGAVMIGATEEAAAVVVLFLIGELLEGVAAGRARASIQGLADLVPKTALV
ERAGGTSECPAEDLAVGDIILVRPGDRIPADGEIIEGASEIDEAPVTGESTPKRKGATDAVFAGTISTDGVLKVRVTAAA
SDNTIARIARLVEEAQEAKAPTERFIDRFSRTYTPAVLAVGALVALLPPLLAGGDWNEWIYKGLAILLIGCPCALVISTP
AAIAAGLATGARRGLLMKGGAVLEGFRRITAVAFDKTGTLTAGKPAVTDIVAYGRDERTVLALAAALEQGSSHPLAMAIL
DRAKADKAPVPPALAAKAISGKGVEGSVGGVAVFLGSGQAAGERADMTQAQRLAVDSLNGQGKTVSVLVADGVVAGLIAM
RDEPRPDAAAGIAALEAESIRAVMLTGDNRRTAQAIAASLGIEARAELLPQDKQRIVGELQREGFKVAKVGDGINDAPAL
AAADIGIAMGGGTDVALETADAAILHGRVMDVARMVKLSRAVMANIGQNITVALGLKAVFLVTTILGITGLWPAILADTG
ATVLVTANAMRLLRWRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-75 44
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-75 44
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 4e-76 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesci_2311 YP_004141509.1 heavy metal translocating P-type ATPase BAC0461 Protein 4e-96 54
Mesci_2311 YP_004141509.1 heavy metal translocating P-type ATPase BAC0298 Protein 1e-77 47