Gene Information

Name : hsdM1 (HIBPF01460)
Accession : YP_004134739.1
Strain : Haemophilus influenzae F3031
Genome accession: NC_014920
Putative virulence/resistance : Virulence
Product : type i restriction-modification system, methyltransferase subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 137059 - 139431 bp
Length : 2373 bp
Strand : +
Note : -

DNA sequence :
ATGGATCATTCTGTTCATAACAAGCTGGTTTCTTTTATTTGGAGTATTGCAGACGATTGTCTGCGCGATGTGTATGTGCG
CGGTAAATATCGTGATGTGATTTTACCGATGTTTGTGCTTCGTCGTTTGGATACTTTACTTGAGCCAAGCAAAGATGCCG
TATTGGAAGAAATGCGTTTTCAAAAAGAAGAATTGGCATTCACCGAATTGGATGACCTTCCCCTTAAAAAAATTACCGGT
CATGTTTTTTATAACACCTCAAAATGGACATTAAAATCCCTCTATCAAACCGCCAGCAATACGCCGCAGTATATGCTGGC
CAATTTTGAAGAATATCTTGATGGTTTCAGCACCAACGTTCATGAAATCATCAACTGCTTCAAGCTGCGTGAACAAATCC
GCCACATGTCCCATAAAAATGTTTTGCTGAGTGTGTTGGAAAAATTTGTATCGCCCTATATCAATCTTACCCCTAAAGAA
CAACAAGACCCTGAGGGCAACAAATTACCAGCGCTGACCAATCTGGGCATGGGCTATGTATTTGAAGAACTGATTCGTAA
ATTTAACGAAGAAAATAACGAAGAAGCTGGCGAACACTTTACCCCACGCGAAGTGATCGAGCTGATGACGCATTTAGTCT
TTGATCCGCTCAAAGACCAAATTCCGGCCATTATTACGATTTACGACCCAGCTTGCGGCAGCGGTGGCATGCTGACCGAG
TCGCAAAACTTTATTGAGCAAAAATATCCGCTATCTGAATCACAAGGCGAGCGTTCCATCTTTTTGTTTGGTAAAGAAAC
CAATGATGAAACCTATGCCATTTGTAAATCTGACATGATGATTAAAGGTGATAATCCCGAAAACATCAAAGTCGGCTCAA
CCCTTGCTACAGATAGCTTCCAAGGTAATCACTTTGACTTTATGCTTTCCAACCCGCCATATGGTAAAAGCTGGAGCAAA
GATCAAGCCTATATCAAAGACGGCAATGAGGTTATCGACAGTCGCTTTAAAGTTACCTTACCAGATTACTGGGGCAATGT
AGAAACCCTTGATGCCACCCCGCGCTCCAGCGATGGTCAGCTGCTTTTCCTGATGGAAATGGTCAACAAAATGAAATCGC
CGAAAAACAACAAAATCGGCAGCCGTGTTGCCTCTGTGCATAACGGCTCAAGCCTGTTTACCGGCGATGCAGGTTCAGGA
GAAAGCAACATTCGTCGCCATATTATTGAAAAAGATTTGCTCGAAGCCATCGTACAGCTGCCTAATAATCTGTTTTATAA
CACAGGCATTACCACTTATATTTGGTTGCTGTCCAACAATAAATCCGAAGCACGCAAAGGCAAAGTTCAGCTGATTGATG
CCAGCCTCTTATTCCGCAAATTGCGTAAAAACCTTGGCGATAAAAACTGCGAATTTGTACCTGAACATATCTCCGAAATT
ACCCAAAACTATCTTGATTTCACCGCCAAAGCGCGCGAAACCGACAGCCAAAATGAAGCGGTCGGTTTGGCTTCGCAGAT
TTTTGACAATCAAGATTTCGGCTATTACAAAGTCACCATCGAACGCCCGGATCGTCGTTCTGCCCAATTTACCGTCGAAA
ATATTGCGTCTTTACGTTTTGACAAAGCCTTGTTTGAGCCGATGCAATATCTTTATCGGCAATATGGCGGACAAGTTTAC
AACGCCAGATTTTTAGCCAAAACCGAGCAAGAAATTACCGCTTGGTGCGAAGCGCAGGGCATAGCCTTAAACAACAAAAA
CAAGGCAAAGCTGCTGGATGTCAAAACGTGGGAAAAAGCCGCCGCACTTTTTCAGACGGCATCAAAACTGCTCGAACATT
TCGGCGAACAACAATTTCACGATTTCAACCAATTCAAACAAGCAGTGGAAGGCCGTCTGAAAACCGAAAAAATCCCCCTT
TCCGCCACAGAGAAAAAGGCCGTTTTCAATGCCGTAAGTTGGTACGACGAAAATTCAGCCAAAGTGATTGCCAAAACACT
CAAACTCAAACCAAACGAATTGGACGCCCTTTGCCAACGCTACCAATGCCAAGCCGACGAGCTGGCAGACTTTGGCTATT
ACGCCACCGGCAAAGCAGGCGAATATATCCTATATGAAACCAGTAGCGACTTGCGCGACAGCGAATCCATACCGCTCAAA
CAAAATATCCACGACTATTTCAAAGCCGAAGTGCAAGCGCACATCAGCGAAGCATGGCTGAATATGGAAAGCGTAAAAAT
CGGCTATGAAATCAGCTTCAACAAATACTTCTACCGCCACAAACCATTACGCAGCCTTGCAGAAGTTGCCCAAGATATTT
TGGCGTTAGAAAAACAGGCTGACGGCTTGATTAGTGAAATTCTAGAGGCTTAA

Protein sequence :
MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRFQKEELAFTELDDLPLKKITG
HVFYNTSKWTLKSLYQTASNTPQYMLANFEEYLDGFSTNVHEIINCFKLREQIRHMSHKNVLLSVLEKFVSPYINLTPKE
QQDPEGNKLPALTNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE
SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSFQGNHFDFMLSNPPYGKSWSK
DQAYIKDGNEVIDSRFKVTLPDYWGNVETLDATPRSSDGQLLFLMEMVNKMKSPKNNKIGSRVASVHNGSSLFTGDAGSG
ESNIRRHIIEKDLLEAIVQLPNNLFYNTGITTYIWLLSNNKSEARKGKVQLIDASLLFRKLRKNLGDKNCEFVPEHISEI
TQNYLDFTAKARETDSQNEAVGLASQIFDNQDFGYYKVTIERPDRRSAQFTVENIASLRFDKALFEPMQYLYRQYGGQVY
NARFLAKTEQEITAWCEAQGIALNNKNKAKLLDVKTWEKAAALFQTASKLLEHFGEQQFHDFNQFKQAVEGRLKTEKIPL
SATEKKAVFNAVSWYDENSAKVIAKTLKLKPNELDALCQRYQCQADELADFGYYATGKAGEYILYETSSDLRDSESIPLK
QNIHDYFKAEVQAHISEAWLNMESVKIGYEISFNKYFYRHKPLRSLAEVAQDILALEKQADGLISEILEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 70
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 70
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 70

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hsdM1 YP_004134739.1 type i restriction-modification system, methyltransferase subunit VFG1102 Protein 0.0 70