Gene Information

Name : Theam_1748 (Theam_1748)
Accession : YP_004134136.1
Strain :
Genome accession: NC_014917
Putative virulence/resistance : Unknown
Product : DNA topoisomerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 15020 - 16966 bp
Length : 1947 bp
Strand : +
Note : SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; TIGRFAM: DNA topoisomerase I; KEGG: pmx:PERMA_1975 DNA topoisomerase I; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-co

DNA sequence :
GTGCTGGTAATCGTTGAGTCTCCCACCAAGGCAAAGAAAATCCAGTCCTTTTTAGGCAAAGGCTACACGGTTAAGGCCAG
TTTAGGCCACGTCAGAGACCTGCCCCCAGACGAATTTGCAGTCTCAATAGAGGCTTTAGAGCAGGGGAAGTTTCCCTTCA
AGTTCAAAGTCCTTGCGGGCAAAGGCAGAGTGGTTAAGGAGCTTCAGAGGCTCGCCTCCGGGGAGCTCGTTCTCTGTGCC
TCAGACCCGGATAGAGAAGGGGAGGCCATCGCTTGGCACTTAGCCCAGCTACTCAAAGAAAAGGCTAAAGAGGTTAAAAG
GATTGAGTTCCACGAAATAACGAAGAAAGCCCTCCAAGAGGCCGTAAAGAGGCCCAGGGAGATAGACCTCAACAGAGTCC
GTGCCCAGTTCGCAAGGAGGGCGATAGACAGGATACTGGGCTACCTGATTAGCCCTGAACTCTCAAAGGAGCTGGGCAAA
AGAGGCCTCTCTGCGGGCAGAGTTCAGTCAACCGCTTTGGCAGAAATCGTCAAGAGAGAGCGGGAGATAAAAGAGTTCGT
CCCCAAGCCCTACTGGGTGGTTGAGGTAGAGCTTGAGAAAGACGGCAAAAAGTTCAGGGCAAGGACTGAGAAGTTCTGGG
ACAAGAAAGAGGCTCAGGAAAACCTCAGGTTCCCCACGCTCCTTGTAATCAGGGCCGATAAGAGAAAGAAACTTGAAAAG
CCCAAGGCTCCCTTTACAGCCTCAGCTCTCCAGCAGGAGGCCAACCGTCTCTTTAAGTGGAGCCCTGAATACACTATGAA
GGTGGCTCAGGAGCTATTTGAGAACGGTTACATAACCTACCACCGTTCAGACTCCCCGAGGCTGTCTGAAGAAGCCGTCG
GCTTTTTAAGGAACCTAATCCCCCGCCTTTTCGGCAAGGACTACCTTCCTGCAAAGCCTTTCGTTTATAAGGCCAAAGAG
GGAGCTCAGGACGCCCACGAGGCAATTAGGCCGACTAAACTCACCCCGGAGGGAGCTCCCGAAAACCTCAAGGACAGGCT
CACTCCTCAGCAGCTAAAGCTCTACACCCTTATCTGGAAAAGAACGCTTGCCTCACAAATGAAAGAGGCCGTCTGGAATA
CTCAAACGGTAGTTCTGCAAAACGACAGGGGAGTCAAGTTCACGGCAAAGGGCAAGACCCTCGTCTTTGAGGGCTGGAGG
AAGGTTTACGACGCTGAAGTGGAGGAAGACGGAGAGGGAATTCTTCCAGAGCTCAGGGTCGGGGAGAAGCTCCCTGCGAA
GCTCAGGCTCAAGGAGGACAAGACAAAGCCCCCGGCCCGCTACACCGAAGGTTCTTTAGTTAAGTGGCTGGAGAAAACTG
GAGTGGGCCGTCCCTCAACCTACGCTTCTACGGTGAAGACCCTGAAGGCAAGAAAGTACGTTGTCGTTAAGGGCGGCAAG
ATGGTTCCAACGGAGACGGCCTTCCGGGTGATTGAGTTCCTTGAGGAAAAACACCCGTGGATACTCTCACCTGAGCTGAC
CGCCCAGATGGAAAAACAGCTTGACCTTGTGGAGCAGGGGAAACTTGACTGGAGAAAGCCTGTTCTGGAGACGGTGGAGA
AGGTTAGGGAGCTTCTGCCTCTCCTATCGGAAGAAAGGGACGACAGGCCTACCGAGAAACAGCTTGAGTTTGCCCGCAGT
TTGGCTGAGAAGCTCAAGAAAGAGCTCCCTGCCGACGTTCTCCTCTCCAAGAAGAAGCTCTCAAAGTGGATAGACGGGGC
AAAGAGGGAGCTTGCCAAGGAAAAGGCCAATGCTCCGCTGTCTGAAAAACAGGTTGCCGTCATAGAGAAGCACGGCGACG
AAAAGGTCAGGGAAGCCCTCCTGAGGGGCGACTACGCCTACTGCCGAAAGTGGCTTGACGGGTTTTTCAGGGAGCTGAAG
AGGAGCGGGAGGAGGAAGAAGAAGTGA

Protein sequence :
MLVIVESPTKAKKIQSFLGKGYTVKASLGHVRDLPPDEFAVSIEALEQGKFPFKFKVLAGKGRVVKELQRLASGELVLCA
SDPDREGEAIAWHLAQLLKEKAKEVKRIEFHEITKKALQEAVKRPREIDLNRVRAQFARRAIDRILGYLISPELSKELGK
RGLSAGRVQSTALAEIVKREREIKEFVPKPYWVVEVELEKDGKKFRARTEKFWDKKEAQENLRFPTLLVIRADKRKKLEK
PKAPFTASALQQEANRLFKWSPEYTMKVAQELFENGYITYHRSDSPRLSEEAVGFLRNLIPRLFGKDYLPAKPFVYKAKE
GAQDAHEAIRPTKLTPEGAPENLKDRLTPQQLKLYTLIWKRTLASQMKEAVWNTQTVVLQNDRGVKFTAKGKTLVFEGWR
KVYDAEVEEDGEGILPELRVGEKLPAKLRLKEDKTKPPARYTEGSLVKWLEKTGVGRPSTYASTVKTLKARKYVVVKGGK
MVPTETAFRVIEFLEEKHPWILSPELTAQMEKQLDLVEQGKLDWRKPVLETVEKVRELLPLLSEERDDRPTEKQLEFARS
LAEKLKKELPADVLLSKKKLSKWIDGAKRELAKEKANAPLSEKQVAVIEKHGDEKVREALLRGDYAYCRKWLDGFFRELK
RSGRRKKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
top ACP28824.1 DNA topoisomerase I Not tested AbaR5 Protein 1e-68 41
topA ADI24145.1 DNA topoisomerase I Not tested AbaR1 Protein 1e-68 41