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Name : GYMC52_3214 (GYMC52_3214) Accession : YP_004133710.1 Strain : Geobacillus sp. Y412MC52 Genome accession: NC_014915 Putative virulence/resistance : Resistance Product : mercuric reductase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : - Position : 3242779 - 3244419 bp Length : 1641 bp Strand : - Note : KEGG: gyc:GYMC61_3185 mercuric reductase; TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Heavy metal transport/detoxification protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region DNA sequence : ATGAAAACATATCGAATGACCGTCCAAGGCATGACATGCACCGGCTGTGAACAACATGTCGCCAGAGCGCTGGGGGCGAT TGGGGCCAAGCTGATGGATGTCAGCTTCCAGCGCAGTGAAGCGGTATTCGCGCTGCCTGAGGGCACGGACGTTGACATGG CGAGACAAGCGGTCAAAAACGCCCATTACGAGCCGGGGGAAGCCGAGGAGATCACCGCATCAGCCAGATCTGTCATCGAT GGCGAGGGAGAGTATGACTACATCGTCATCGGTTCCGGCGGGGCGGCGTTTTCCTCGGCGATCGAAGCGGTGAAATACGG GGCGAAAGTGGCGATGGTCGAACGTGGCACGGTCGGGGGGACGTGCGTCAATATCGGCTGCGTGCCGTCAAAGACATTGC TTCGGGCTGGTGAAATCAATGCGTTGGCGCGAAATCATCCGTTTCTCGGCCTGCATACATCCGCTGGTCCGGTTGATTTG GCGCCGTTAGTGAAGCAAAAAAATGAGCTGGTCGAGCAGCTTCGCCAAGCGAAATATGCAGACTTGATCGGAGAGTATGG GTTCGATTTCATCCAAGGGGAAGCCCGATTTGTTGGGCGCCAAACGATTGAAGTGAACGGCCAAACGCTGTCGGCGAAAC GGTTTTTGATCGCGACAGGCGCTTCCCCGGCTGTGCCGGATATTCGGGGGCTTCATGATGTCGACTACTTGACCAGCACG ACGTTGCTCGAGCTGAAAAAGGTGCCGAAGCGGCTCGCCGTCATCGGCGCCGGCTACATCGGTATGGAGTTGGGACAACT GTTCCACCATCTCGGCTCGGAGGTGACGTTGATGCAGCGAAGCCCACGCCTGCTGAAAGAGTATGACCCGGAAATTTCCG AAGCGGTGGCGCGGGCGCTCACGGAACAAGGCATCCGCATCATCACCGGCGCTTCGTTTGAACGGGTCGAACAAGACGGG AATACGAAAAAAGTGTATGTGAATGTAGACGGCCGCACCCGGGTCATCGAAGCGGACGAATTGCTCGTGGCTGCCGGGAG AACGCCGAATACGGCGGCGTTGAACTTGCCAGCAGCCGGTGTGGAAGTCGGGGCGCGCGGGGAAATTTTGATCGACGAAT ATACACGGACGACGAACCCGTCGATTTATGCGGCAGGCGATGTCACGCTCGGCCCGCAGTTCGTCTATGTCGCGGCCTAT CAGGGAGCCGTTGCCGCGGCCAATGCCGTCGGCGGGCTGAACAAGCGCTGGGATACGGCCGTCGTTCCGGCGGTGACGTT CACCCATCCGGCCATCGCCACCGTCGGGTTGACCGAACAGCGGGCGAAAGAAAACGGGTATGACGTGAAAACGTCCGTCC TGCCGCTTGAGGCGGTGCCGCGCGCGATCGTCAACCGGGAAACGACGGGGGTGTTTAAACTTGTCGCTGAGGCCCGTACG GGCAAGCTGCTAGGCGCCCACGTTGTTGCGGACAATGCCGGCGAGGTCATTTACGCTGCGACGTTGGCGATTCAATTCGG ATTAACGATCGACGACCTTCGCCGCACGTTGGCTCCGTATTTAACGATGGCGGAGGGGCTGAAGCTGGCGGCGCTTACGT TTGACCAAGATGTTTCGAAGTTATCGTGCTGCGCGGGATGA Protein sequence : MKTYRMTVQGMTCTGCEQHVARALGAIGAKLMDVSFQRSEAVFALPEGTDVDMARQAVKNAHYEPGEAEEITASARSVID GEGEYDYIVIGSGGAAFSSAIEAVKYGAKVAMVERGTVGGTCVNIGCVPSKTLLRAGEINALARNHPFLGLHTSAGPVDL APLVKQKNELVEQLRQAKYADLIGEYGFDFIQGEARFVGRQTIEVNGQTLSAKRFLIATGASPAVPDIRGLHDVDYLTST TLLELKKVPKRLAVIGAGYIGMELGQLFHHLGSEVTLMQRSPRLLKEYDPEISEAVARALTEQGIRIITGASFERVEQDG NTKKVYVNVDGRTRVIEADELLVAAGRTPNTAALNLPAAGVEVGARGEILIDEYTRTTNPSIYAAGDVTLGPQFVYVAAY QGAVAAANAVGGLNKRWDTAVVPAVTFTHPAIATVGLTEQRAKENGYDVKTSVLPLEAVPRAIVNRETTGVFKLVAEART GKLLGAHVVADNAGEVIYAATLAIQFGLTIDDLRRTLAPYLTMAEGLKLAALTFDQDVSKLSCCAG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 2e-177 | 65 |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 3e-177 | 65 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 2e-81 | 44 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 5e-83 | 44 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 1e-82 | 43 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 1e-82 | 43 |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 1e-82 | 43 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 2e-79 | 43 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 2e-79 | 43 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 2e-79 | 43 |
| unnamed | ABR13401.1 | mercuric reductase | Not tested | PAGI-5 | Protein | 7e-79 | 42 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 8e-82 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| GYMC52_3214 | YP_004133710.1 | mercuric reductase | BAC0224 | Protein | 0.0 | 70 |
| GYMC52_3214 | YP_004133710.1 | mercuric reductase | BAC0651 | Protein | 1e-177 | 65 |
| GYMC52_3214 | YP_004133710.1 | mercuric reductase | BAC0652 | Protein | 3e-80 | 43 |
| GYMC52_3214 | YP_004133710.1 | mercuric reductase | BAC0653 | Protein | 9e-80 | 41 |
| GYMC52_3214 | YP_004133710.1 | mercuric reductase | BAC0650 | Protein | 4e-76 | 41 |
