Gene Information

Name : GYMC52_2774 (GYMC52_2774)
Accession : YP_004133294.1
Strain : Geobacillus sp. Y412MC52
Genome accession: NC_014915
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 2830512 - 2832275 bp
Length : 1764 bp
Strand : -
Note : KEGG: gyc:GYMC61_0778 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
ATGAAGCGGAAAACGAAAATCGTCTGTACGATCGGGCCGGCAAGCGAGAGCGTAGACAAGCTCGTGCAATTGATCGAAGC
GGGGATGAACGTGGCGCGCCTCAACTTTTCGCACGGAGATCATGAGGAACACGGGCGGCGCATCGCCAACATTCGCGAGG
CGGCGAGGCGGACGGGCCAAACGGTCGCCATTTTGCTCGATACGAAAGGTCCGGAAATCCGCACGCACAATATGGAGAAC
GGCGCCATCGAACTGAAGGAAGGGGCAAAGCTCATCATTTCGATGAGCGAAGTGCTCGGCACGCCGGAAAAAATTTCTGT
CACCTATCCGGGGCTGATCGATGATGTGTCCGTTGGTTCGAAAATTTTGCTGGACGACGGGTTGATCGGCCTTGAAGTCA
ACGCGGTCGACAAGCAAGCTGGAGAAATTGTCACGACCGTCTTAAACAGCGGTGTGCTCAAAAACAAAAAAGGGGTCAAT
GTCCCCGGCGTGCGTGTCAATTTGCCGGGCATCACCGAGAAGGACCGAGCCGATATTTTATTTGGCATCCGCCAAGGCAT
CGACTTCATCGCCGCCTCGTTTGTGCGCCGGGCGTCTGATGTGCTCGAAATCCGCGAGCTGCTCGAGGCGAATGACGCCT
TACATATCCAAATTATCGCGAAAATTGAAAATGAAGAAGGCGTCGCCAACATCGATGAAATTTTGGAAGCCGCCGATGGC
CTCATGGTGGCGCGCGGCGACCTTGGCGTTGAGATTCCGGCTGAGGAAGTGCCTCTCATTCAAAAAATGCTCATTAAAAA
GTGCAACATGCTTGGCAAGCCGGTCATCACAGCGACGCAAATGCTCGACTCGATGCAGCGCAATCCGCGGCCGACGCGGG
CTGAGGCGAGCGATGTCGCCAACGCCATTTTTGACGGCACCGACGCCGTCATGCTTTCCGGAGAAACCGCAGCCGGCCAG
TATCCGGTCGAAGCGGTAAGGACGATGCACCAAATCGCGCTCCGCACCGAGCAGGCGTTGGAGCATCGCGACATTTTGTC
CCAGCGCACGAAAGAGAGCCGAACGACGATCACCGATGCCATCGGCCAATCGGTCGCCCACACGGCGCTCAATTTGGATG
TCGCGGCGATCGTGACGCCGACGGTGAGCGGAAAAACGCCGCAGATGGTGGCGAAATACCGCCCGAAAGCCCCGATCATC
GCGGTGACATCAAACGAAGCGGTCTCGCGGCGGCTGGCGCTCATTTGGGGCGTGTATACGAAAGAAGCACCGCATGTCAA
TACAACCGATGAAATGCTCGATGTGGCGGTCGACGCGGCAGTGCGCTCCGGCTTGGTGAAGCACGGCGACTTGGTCGTCA
TCACGGCCGGCGTGCCGGTCGGCGAAACGGGATCGACGAACTTAATGAAAGTGCACGTCATCAGCGACTTGCTTGCCAAA
GGGCAAGGCATCGGCCGCAAGTCGGCATTCGGCAAGGCGGTCGTCGCCAAAACGGCGGAAGAGGCGTGCCGAAAAATGGT
AGAGGGCGGCATTTTAGTCACCATCAGCACCGATGCCGATATGATGCCGGCTCTCGAAAAAGCAGCGGCGATCATTACTG
AGGAAGGCGGGTTGACGAGCCATGCGGCGGTCGTCGGCTTAAGCCTTGGCATTCCGGTCGTCGTCGGGGTGGAAAATGCC
ACAAGCTTGTTTAAAGATGGGCAAGAGATCACGGTCGATGGCGGCTTTGGCGCCGTCTACCGCGGCCATGCGAGCGTGTT
GTAA

Protein sequence :
MKRKTKIVCTIGPASESVDKLVQLIEAGMNVARLNFSHGDHEEHGRRIANIREAARRTGQTVAILLDTKGPEIRTHNMEN
GAIELKEGAKLIISMSEVLGTPEKISVTYPGLIDDVSVGSKILLDDGLIGLEVNAVDKQAGEIVTTVLNSGVLKNKKGVN
VPGVRVNLPGITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELLEANDALHIQIIAKIENEEGVANIDEILEAADG
LMVARGDLGVEIPAEEVPLIQKMLIKKCNMLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAVMLSGETAAGQ
YPVEAVRTMHQIALRTEQALEHRDILSQRTKESRTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPII
AVTSNEAVSRRLALIWGVYTKEAPHVNTTDEMLDVAVDAAVRSGLVKHGDLVVITAGVPVGETGSTNLMKVHVISDLLAK
GQGIGRKSAFGKAVVAKTAEEACRKMVEGGILVTISTDADMMPALEKAAAIITEEGGLTSHAAVVGLSLGIPVVVGVENA
TSLFKDGQEITVDGGFGAVYRGHASVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-108 53
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-108 53
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-108 53
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-108 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GYMC52_2774 YP_004133294.1 pyruvate kinase VFG0479 Protein 2e-108 53