Gene Information

Name : GYMC52_2379 (GYMC52_2379)
Accession : YP_004132909.1
Strain : Geobacillus sp. Y412MC52
Genome accession: NC_014915
Putative virulence/resistance : Unknown
Product : adenine-specific DNA-methyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 2446022 - 2447515 bp
Length : 1494 bp
Strand : -
Note : KEGG: gyc:GYMC61_0286 site-specific DNA-methyltransferase (adenine-specific); PFAM: N-6 DNA methylase

DNA sequence :
ATGGCGACGATCGGTTTTGAAGAAAAGTTATGGTCCGCAGCCGATAAGCTGCGAAACAATATGGATGCGGCAGAATATAA
ACACGTCGTCTTAGGGCTTATTTTCTTAAAATACGTGTCTGATACGTTTCAAGAAAAATGGGAAGAACTGATGAAAGAAG
ATCCCGATTTTGCGGAAGACCGCGACGCGTATATGGCGGACGGAGTGTTTTGGGTGCCGGAAACGGCCCGTTGGAGCTAT
ATAGCGGAACGTTCGAAGTCGCCGGAAATCGGAAAAATTGTCGATGAGGCGTTGGATGCAATCGAAAAAGAGAATGACAG
TTTAAAAGGAGTGCTCCCGAAAAACTACTCCCGCCCTGAGTTAGACAAGCGCATTTTAGGGGAAATTATTGACTTGTTTT
CCAATATTGACGTCGGCGGCAGCGGGGCAAAGGAAAAAGACGTCTTAGGGCGGGTGTACGAATACTTCTTAGGCAAATTT
GCGGCCAGCGAAGGAAAAGGAGGAGGCGAGTTTTACACGCCGAAATGCGTCGTCAAACTGATGGTCGAAATGATTCAGCC
GTTCAAAGGGTATGTGTACGACCCGGCATGCGGCAGCGGCGGGATGTTCGTCCAGTCGATGAAATTCGTCGAAGAACATG
CGGGAAACAAGTTTGATATTTCCATTTACGGCCAAGAATCGAACCCAACGACATGGAAGCTCGCCAAAATGAACTTGGCG
ATTCGCGGCATTGAAAACAATCTCGGTCCGAAACATGCCGACACGTTTCATGAAGACTTGCATCCGACGTTAAAAGCGGA
CTATATTTTAGCGAATCCACCGTTTAATGACAGCGACTGGGGGCAACCGAAATTAATCGACGACCCACGCTGGAAATTTG
GTATTCCACCAGCTGGAAACGCCAACTACGCCTGGCTGCAGCATATGATCGACAAGCTTAGCCAAAACGGAAAAGCGGCG
GTTGTGCTGGCGAACGGCTCGCTGTCCTCGATGACGTCCGGCGAAGGGGAGATTCGCAAAAACATTGTCAACGCAGATTT
AGTCGACGCGATCATCGCGTTGCCGGATAAATTGTTTTACACAACGCAAATCCCGGTGTGCATTTGGATTTTAAACCGCA
ACAAGAAACATCCGAGGAAAACGTTATTCATCGATGCGCGCAAATTCGGCCAGCTCGTCACCCGGAAGTTGCGAGAGTTG
ACGGATGAGGATATCCGCAAAATCGCCGATACGTATATCAATTGGCAAAACAACGAGAACTACGAAGACGTGCAAGGCTT
TTGCAAATCAGCGACGATCGACGACATTCGCGAGCACAACTACATCCTCACGCCCGGCCGCTACGTCGGCATTGAAGAAG
AGGAAGAAGACGGGGAATCGTTTGAGGAAAAAATGGAGCGGCTGACAGCGACATTGGCGAAGCAATTTCAAAAATCGCGC
CAGTTGGAAGAAGAAATTCGCAAGCAGTTGGGGGGGATAGGGTATGAGATATGA

Protein sequence :
MATIGFEEKLWSAADKLRNNMDAAEYKHVVLGLIFLKYVSDTFQEKWEELMKEDPDFAEDRDAYMADGVFWVPETARWSY
IAERSKSPEIGKIVDEALDAIEKENDSLKGVLPKNYSRPELDKRILGEIIDLFSNIDVGGSGAKEKDVLGRVYEYFLGKF
AASEGKGGGEFYTPKCVVKLMVEMIQPFKGYVYDPACGSGGMFVQSMKFVEEHAGNKFDISIYGQESNPTTWKLAKMNLA
IRGIENNLGPKHADTFHEDLHPTLKADYILANPPFNDSDWGQPKLIDDPRWKFGIPPAGNANYAWLQHMIDKLSQNGKAA
VVLANGSLSSMTSGEGEIRKNIVNADLVDAIIALPDKLFYTTQIPVCIWILNRNKKHPRKTLFIDARKFGQLVTRKLREL
TDEDIRKIADTYINWQNNENYEDVQGFCKSATIDDIREHNYILTPGRYVGIEEEEEDGESFEEKMERLTATLAKQFQKSR
QLEEEIRKQLGGIGYEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-157 63
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 2e-159 63
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-158 62
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 9e-117 50