Gene Information

Name : GYMC52_2137 (GYMC52_2137)
Accession : YP_004132682.1
Strain : Geobacillus sp. Y412MC52
Genome accession: NC_014915
Putative virulence/resistance : Virulence
Product : two component transcriptional regulator, winged helix family
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2218987 - 2219661 bp
Length : 675 bp
Strand : -
Note : KEGG: gct:GC56T3_1345 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver

DNA sequence :
ATGAACGGACGTATTTTATTGATTGAAGATGAAGCCGGGCTCGCCCGGTTTTTGGAGCTTGACTTAAAGCACGAAGGCTT
TGACGTGCATGTATGCGCCGATGGACGCGAAGGGCTCGAGCTCGCTCTTTCGGAGCAGTGGGATCTCATTTTGCTTGATG
TGATGCTGCCTAGTCTCAATGGCATGGAAGTATGCCGCCGCATCCGGGCGGCGAAATCGACGCCGATCATGATGATCACA
GCGCGCGACAGCGTGTTTGACCGCGTCATGGGGCTCGATAACGGGGCCGATGACTACATCGTCAAACCGTTTGCCATTGA
AGAGCTGCTCGCCCGCATCCGCGCCTTGTTCCGCCGCGTTCATCCAGAAGCGAACGCCCAAGTGTTGACGTTTAAAGATT
TAGTCGTTGACGTGCAGGCGCGCACCGTGAAAAAAGGAGACGAATTTATTGAGCTGACGAAGCGGGAATACGACTTGCTC
GTCGCCTTTATGCAAAACATCAATGTCGTCTTGACGCGTGATGCGCTGCTTGACAAAGTGTGGGGATTTGACGCCGAAGT
CGAGACGAACGTCGTCGATGTGTATGTCCGCTACTTGCGGCAAAAGCTTGACGAACACGATAAAGAGCGGTATATCCAAA
CGGTGCGCGGCACGGGATATGTGATGCGGCCATGA

Protein sequence :
MNGRILLIEDEAGLARFLELDLKHEGFDVHVCADGREGLELALSEQWDLILLDVMLPSLNGMEVCRRIRAAKSTPIMMIT
ARDSVFDRVMGLDNGADDYIVKPFAIEELLARIRALFRRVHPEANAQVLTFKDLVVDVQARTVKKGDEFIELTKREYDLL
VAFMQNINVVLTRDALLDKVWGFDAEVETNVVDVYVRYLRQKLDEHDKERYIQTVRGTGYVMRP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 3e-35 43
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-34 43
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 9e-36 41
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 6e-36 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family HE999704.1.gene1528. Protein 6e-70 66
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_003923.1003417.p0 Protein 2e-56 55
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_013450.8614146.p0 Protein 2e-56 55
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_002951.3238224.p0 Protein 2e-56 55
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_007793.3914065.p0 Protein 2e-56 55
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_002758.1121390.p0 Protein 2e-56 55
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_010079.5776364.p0 Protein 2e-56 55
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_002952.2859858.p0 Protein 2e-56 55
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_007622.3794948.p0 Protein 2e-56 55
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family AE015929.1.gene1106. Protein 7e-53 54
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family BAC0125 Protein 2e-38 44
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family BAC0308 Protein 3e-38 44
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family AE000516.2.gene3505. Protein 2e-38 44
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family BAC0197 Protein 5e-36 43
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family CP001485.1.gene721.p Protein 1e-32 42
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_012469.1.7686381. Protein 2e-44 42
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family NC_012469.1.7685629. Protein 3e-40 42
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family BAC0083 Protein 1e-38 42
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family HE999704.1.gene2815. Protein 3e-39 41
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family BAC0111 Protein 2e-37 41
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family BAC0638 Protein 8e-36 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family VFG1390 Protein 2e-47 47
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family VFG0596 Protein 1e-35 43
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family VFG1389 Protein 2e-39 43
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family VFG1563 Protein 5e-36 41
GYMC52_2137 YP_004132682.1 two component transcriptional regulator, winged helix family VFG1702 Protein 2e-36 41