Gene Information

Name : GYMC52_1901 (GYMC52_1901)
Accession : YP_004132465.1
Strain : Geobacillus sp. Y412MC52
Genome accession: NC_014915
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1965764 - 1967473 bp
Length : 1710 bp
Strand : -
Note : TIGRFAM: urease subunit alpha; KEGG: gyc:GYMC61_2771 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein

DNA sequence :
ATGAGTTTTTCCATGTCAAGACGGCAATACGCGGATATGTTTGGGCCGACGACTGGGGACTGCATCCGGTTGGCGGATAC
TGACTTATGGATTGAAATTGAGCATGACTATACGGTTTACGGCGATGAAGTGAAATTCGGCGGCGGGAAGGTGATTCGCG
ACGGGATGGGGCAACATCCGCTCGCAACCCGCGACGAAGCGGTCGATTTAGTGCTGACGAATGCCGTCATCGTTGATTAC
ACCGGCATTTACAAAGCCGATATCGGGATCAAAGATGGAAACATCGCCGCCATCGGCAAGGCTGGGAATCCGCTGTTAAT
GGATGGCGTCAATATTGTCATCGGCGCCTCAACGGAAGTGATCGCGGCGGAAGGAAAAATCGTGACAGCCGGCGGGGTCG
ACGCCCATATCCATTTCATTTGCCCGCAGCAAATCGAAACTGCTCTGTCATCGGGCATTACGACGATGATCGGCGGCGGG
ACCGGGCCGGCGACCGGAACGAATGCCACGACGTGCACGCCGGGAGAGTGGAACATTTACCGGATGCTTGAAGCCGCCGA
AGCGTTCCCGATGAATATCGGTTTTTTAGGAAAAGGCAACGCATCGGCGAAAGAGCCGATCGCTGAGCAAGTCCGCGCCG
GAGCGATTGGACTCAAACTTCATGAAGACTGGGGAACGACGGCGGCGGCGATTGATGCGTGCTTGCGAGTGGCGGATGAG
TACGATGTGCAAGTCGCCATTCATACCGATACATTGAATGAAGGCGGGTTTGTCGAGCATACACTGAAGGCCATTAACGG
GCGCGTCATTCATACATATCATACGGAAGGAGCCGGAGGGGGGCATGCGCCCGATATTATGAAAGTCGCCAGCTTCCCGA
ACATTTTGCCTTCTTCCACGAATCCGACGCGGCCGTATACGAAAAACACGGTTGATGAGCATTTAGATATGTTAATGGTG
TGCCATCATTTAGATCCGTCCGTTCCGGAAGACATTGCCTTTGCCGATTCGCGCATCCGCAAAGAAACGATCGCTGCTGA
AGATATTTTGCACGACATCGGCGCCTTCAGCATGATCAGTTCCGACTCGCAAGCGATGGGGCGCGTCGGTGAAGTCATTT
TACGCACGTGGCAAACGGCCGACAAAATGAAAAAACAGTTTGGCCGCTTGCCGGAGGAAACGGGGCGGGGCGATAATGTC
CGCGTCAAACGGTATGTAGCCAAATACACGATCAATCCAGCCATTACGCATGGGATTGCCGAATATGTCGGCTCGGTGGA
AGTCGGAAAATTCGCGGATTTGGTCGTTTGGCATCCCGCTTTTTTCGGGGTCAAGCCTGAGCTCGTCATCAAAGGCGGGA
TGATCGCCTACAGCGTGATGGGCGACCCGAACGCCAGCATTCCGACGCCGCAGCCCGCGCTGTACCGCCCGATGTTCGCC
AGCTATGGCGCCGCCATCGCGAAAACGTCCATCACCTTTTTATCCAAAGCGGCGTTCGAGCGCGGCATTCCTGACAAGCT
GGGGCTGCACAAAATCGTCAAACCGGTTGGAAACATTCGCTCGTTGACGAAACACGATATGGTATTCAACAACGCCATGC
CCCAAATCGATGTCGATCCGCAGACGTATGAAGTGAAGGTCGACGGGCGGCTCATTACGTGCGAGCCGGCCGAAGTGGTG
GCCATGGCGCAACGATATTTTCTTTTTTGA

Protein sequence :
MSFSMSRRQYADMFGPTTGDCIRLADTDLWIEIEHDYTVYGDEVKFGGGKVIRDGMGQHPLATRDEAVDLVLTNAVIVDY
TGIYKADIGIKDGNIAAIGKAGNPLLMDGVNIVIGASTEVIAAEGKIVTAGGVDAHIHFICPQQIETALSSGITTMIGGG
TGPATGTNATTCTPGEWNIYRMLEAAEAFPMNIGFLGKGNASAKEPIAEQVRAGAIGLKLHEDWGTTAAAIDACLRVADE
YDVQVAIHTDTLNEGGFVEHTLKAINGRVIHTYHTEGAGGGHAPDIMKVASFPNILPSSTNPTRPYTKNTVDEHLDMLMV
CHHLDPSVPEDIAFADSRIRKETIAAEDILHDIGAFSMISSDSQAMGRVGEVILRTWQTADKMKKQFGRLPEETGRGDNV
RVKRYVAKYTINPAITHGIAEYVGSVEVGKFADLVVWHPAFFGVKPELVIKGGMIAYSVMGDPNASIPTPQPALYRPMFA
SYGAAIAKTSITFLSKAAFERGIPDKLGLHKIVKPVGNIRSLTKHDMVFNNAMPQIDVDPQTYEVKVDGRLITCEPAEVV
AMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 5e-178 69
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 5e-178 69
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-175 66
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-177 66
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 7e-177 66
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-177 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GYMC52_1901 YP_004132465.1 urease subunit alpha VFG0270 Protein 2e-164 66