Gene Information

Name : Alide_4499 (Alide_4499)
Accession : YP_004129077.1
Strain :
Genome accession: NC_014911
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 70303 - 71949 bp
Length : 1647 bp
Strand : -
Note : KEGG: enc:ECL_A232 mercuric reductase; TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Heavy metal transport/detoxification protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region

DNA sequence : 
ATGACCGAAATCACCGTGAATGGCATGACCTGCACATCCTGCGCCACCCATGTCAAAGATGCTTTGGAAAAGATTCCCGG
CGTGAATGCCGCTGTGGTGTCCTATCCAGAAAGCCGCGCGCAAGTCATGGCAGACACCGCCGTGAGCCACAACCAACTGC
TGGCCGCCATCGCCGCATTGGGTTATCAAGGCTCGATCCGGGTTGGTGATTTCAAAGATGAACCAAAAATCCGTGATGCA
CTTGAGGGCGCCGGTTTGCATATCGCCATCATTGGCAGCGGCGGGGCCGCGATGGCGGCGGCGCTGAAGGCCGTCGAGCA
AGGCGCGACGGTCACGCTGATCGAACGCGGCACCATCGGCGGCACCTGCGTCAATATCGGCTGTGTGCCGTCCAAGATCA
TGATCCGCGCTGCCCATATTGCCCATCTGCGCCGGGAAAGTCCGTTCGACGGCGGTATTGCGGCAACTGTGCCTGCGATT
GACCGCAGCAAACTGCTGGCCCAGCAGCAGGCCCGTGTCGATGAACTGCGGCACGCCAAATACGAAGGCATCCTGGACGG
CAATCCAGCCATCACCGTTTTGCACGGTGAAGCGCGTTTCAAGGACGACCAGAGCCTGGTCGTCCGTTTGAACGAGGGTG
GCGAGCGCGAGGTAACGTTCGACCGCTGCCTGGTCGCCACCGGTGCCAGTCCGGCCGTGCCGCCGATTCCGGGCCTGAAA
GAGTCACCCTACTGGACTTCCACCGAAGCGCTTGTCAGCGACACCATTCCCGCACGCCTGGCCGTGATCGGTTCGTCGGT
GGTGGCGTTGGAACTGGCGCAAGCCTTTGCCCGGCTCGGCAGCCAGGTCACGATCCTGGCACGCAGCACCTTGTTCTTCC
GGGAAGACCCGGCCATCGGCGAGGCCGTGACAGCCGCTTTCCGCGCCGAGGGCATCGAGGTGCTGGAGCACACGCAAGCC
AGCCAGGTCGCCCATGTGAACGGCGAATTCGTGCTGACCACCGGACACGGTGAATTGCGCGCTGACAAGTTGCTGGTTGC
CACCGGTCGGGCACCGAATACGCGCAGCCTCGCGCTGGACGCGGCGGGGGTCACTGTCAATGCGCAAGGGGCCATCGTTA
TCGACCAAGGCATGCGCACGAGCAACCCGAACATCTACGCGGCCGGCGACTGCACCGACCAGCCGCAGTTCGTCTACGTG
GCAGCGGCCGCCGGCACCCGTGCCGCGATCAACATGACCGGCGGCGACGCAGCCCTCAATCTGACCGCGATGCCGGCAGT
GGTGTTCACCGACCCGCAAGTCGCCACCGTGGGCTACAGCGAGGCGGAAGCGCACCACGATGGCATCGAGACCGACAGTC
GCACGCTGACACTCGACAACGTTCCGCGAGCGCTTGCCAACTTCGACACACGCGGCTTCATCAAGCTGGTCATCGAGGAA
GGTAGCGGACGGCTCATCGGCGTGCAGGCGGTGGCCCCGGAAGCGGGCGAACTGATCCAGACGGCGGTGCTCGCCATCCG
CAACCGCATGACGGTGCAGGAACTGGCCGACCAGTTGTTCCCCTACCTGACAATGGTCGAGGGGTTGAAGCTTGCGGCGC
AGACCTTCAACAAGGACGTGAAGCAGCTTTCCTGCTGCGCTGGATAA

Protein sequence : 
MTEITVNGMTCTSCATHVKDALEKIPGVNAAVVSYPESRAQVMADTAVSHNQLLAAIAALGYQGSIRVGDFKDEPKIRDA
LEGAGLHIAIIGSGGAAMAAALKAVEQGATVTLIERGTIGGTCVNIGCVPSKIMIRAAHIAHLRRESPFDGGIAATVPAI
DRSKLLAQQQARVDELRHAKYEGILDGNPAITVLHGEARFKDDQSLVVRLNEGGEREVTFDRCLVATGASPAVPPIPGLK
ESPYWTSTEALVSDTIPARLAVIGSSVVALELAQAFARLGSQVTILARSTLFFREDPAIGEAVTAAFRAEGIEVLEHTQA
SQVAHVNGEFVLTTGHGELRADKLLVATGRAPNTRSLALDAAGVTVNAQGAIVIDQGMRTSNPNIYAAGDCTDQPQFVYV
AAAAGTRAAINMTGGDAALNLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEE
GSGRLIGVQAVAPEAGELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 84
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 84
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 84
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 83
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 81
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 79
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 79
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 79
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 78
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 75

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Alide_4499 YP_004129077.1 mercuric reductase BAC0652 Protein 0.0 84
Alide_4499 YP_004129077.1 mercuric reductase BAC0653 Protein 0.0 82
Alide_4499 YP_004129077.1 mercuric reductase BAC0650 Protein 2e-172 67
Alide_4499 YP_004129077.1 mercuric reductase BAC0224 Protein 3e-83 41