Gene Information

Name : Alide_4159 (Alide_4159)
Accession : YP_004128748.1
Strain : Alicycliphilus denitrificans BC
Genome accession: NC_014910
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 4350079 - 4351521 bp
Length : 1443 bp
Strand : -
Note : TIGRFAM: pyruvate kinase; KEGG: dia:Dtpsy_3305 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence : 
ATGTCCATGCGAAGCCGCCGCGCCACCAAAATCGTCGCCACCCTGGGCCCCGCCTCCAGCGACCCGCTGCTGCTGGAGCA
GATGATCGCGGCGGGCGTGAACGTGGTGCGCTTGAACTTCAGCCACGGCAAGGCGCGCGACCACGTGGAGCGCGCCGCCA
AGGTGCGCGAGGCCGCCCAGCGCGCCGGGCGCGAGGTGGCCATCATGGCCGACCTGCAGGGCCCCAAGATCCGCGTGGGC
AAGTTCGCCGAGGGGCGCGTGCACCTGGAGGTGGGGCAGCCGTTCGTCCTCGACGCCTCGCGCACCGAGCCCGGCGACCT
GCAGGGCGTGGGGCTGGACTACAAGGAGCTGCCGCGCGACGTGAGGGCGGGCGACGTGCTGCTGCTCAACGACGGCCTGA
TCGTGCTGCAGGTCGATGCGGTGCGCGGCGAGGCCGTGCACACCACGGTGAGGATAGGCGGCGAGCTGTCCAACAACAAG
GGCATCAACAAGCAGGGCGGGGGCCTGACGGCGCCGGCCCTCACGGCCAAGGACATGGAGGACATCAAGACGGCGATGAG
CTTCCAGGCCGACTACGTGGCCGTGAGCTTTCCCAAGAACGCCACCGACATGGAGATGGCGCGCCAGCTGTGCAACGTGG
CGGCCGCCGAGTTCCGCCACAAGCCCGGGCTGATCGCGAAGATAGAGCGCGCCGAGGCCATTCCGCGCCTCGAAGAGATC
CTGCACGTATCCGACGGCATCATGGTCGCGCGCGGCGATCTGGCCGTGGAGGTGGGCAACGCCGCCGTGCCGGCGCTGCA
GAAGAAGATGATCCGCATGGCGCGCGACATGGACAAGGTCGTGATCACCGCCACCCAGATGATGGAGAGCATGATCTCCA
ACCCCGTGCCCACGCGCGCCGAGGTCAGCGACGTGGCCAACGCCGTGCTCGACGGCACCGACGCCGTGATGCTCAGCGCC
GAGACGGCCGCCGGCAAGTATCCGCTGGAGACGGTGCAGGAGATGGCCAAGATCTGCGCCGCCGCCGAGGCCGCAGAGGA
CCCCGACCGCGACGCCGACTTCGACGGCCAGACGGCGGGCCGCGTCGACCAGTCCGTGGCCATGGGCGCGCTGTTCACCG
CCCACCACCTGGGCGCCAAGGCCATCGTGGCCATGACCGACAGCGGCTCCACGGCCCTGTGGATGAGCCGCCACCGCATC
CACATCCCGATCTACGCGCTGACGCCCAAGGTGGCCACGCAGCGGCGCATGGCCATGTTCCGCAATGTGCGCCCCCTGCT
CATGGACACCAGCGCCGACCGCGACACGGCCCTGGAGCAGGCCGAGAACCACCTGAAGATGCGCAACATCGTGCAGCAGG
GCGACCTGTACGTGATTACCTGCGGCGAGCCCATGGGCGCGCCGGGCGGCACGAACATGCTCAAGATCTGCCGGGCGCGG
TGA

Protein sequence : 
MSMRSRRATKIVATLGPASSDPLLLEQMIAAGVNVVRLNFSHGKARDHVERAAKVREAAQRAGREVAIMADLQGPKIRVG
KFAEGRVHLEVGQPFVLDASRTEPGDLQGVGLDYKELPRDVRAGDVLLLNDGLIVLQVDAVRGEAVHTTVRIGGELSNNK
GINKQGGGLTAPALTAKDMEDIKTAMSFQADYVAVSFPKNATDMEMARQLCNVAAAEFRHKPGLIAKIERAEAIPRLEEI
LHVSDGIMVARGDLAVEVGNAAVPALQKKMIRMARDMDKVVITATQMMESMISNPVPTRAEVSDVANAVLDGTDAVMLSA
ETAAGKYPLETVQEMAKICAAAEAAEDPDRDADFDGQTAGRVDQSVAMGALFTAHHLGAKAIVAMTDSGSTALWMSRHRI
HIPIYALTPKVATQRRMAMFRNVRPLLMDTSADRDTALEQAENHLKMRNIVQQGDLYVITCGEPMGAPGGTNMLKICRAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-112 57
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-60 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-61 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-61 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Alide_4159 YP_004128748.1 pyruvate kinase VFG0479 Protein 2e-61 41