Gene Information

Name : Alide_2714 (Alide_2714)
Accession : YP_004127332.1
Strain : Alicycliphilus denitrificans BC
Genome accession: NC_014910
Putative virulence/resistance : Unknown
Product : DNA topoisomerase iii
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 2806679 - 2808694 bp
Length : 2016 bp
Strand : -
Note : TIGRFAM: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; DNA topoisomerase type IA zn finger domain protein; KEGG: ajs:Ajs_2233 DNA topoisomerase III; SMART: DNA topoisomerase I DNA-binding;

DNA sequence :
ATGCGCGTGTTCCTGTGCGAGAAGCCGTCCCAGGGCAAGGACATCGCCCGTGTGCTGGGCGCCGGCCAACGCAGCAACGG
CTGCTACAGCGGTGCCGGTGTTGTCGTGACCTGGTGCATTGGTCATCTGGTCGAGGCGGTTCCGCCCGAAGGCTACGGCG
AGCAGTACAAGCGCTGGGCCATCGAGCAGCTGCCCATTGTTCCTGAGCGTTGGCGTGTCGAGCCCAAGGTGGCGACCGCA
GCGCAATTCAAGGTCGTGCAGCAGCTCGTCGCCAAGGCGGGCGAGCTAGTGATTGCGACCGACGCCGACCGCGAGGGCGA
GATGATCGCCCGCGAGATCATCGACCTATGCGGCTACCGCGGGCCGATTCAGCGCCTGTGGCTGTCGGCGCTCAACGATG
CGTCGATCCGTAAAGCGCTGGGTGCGCTCAAGCCGTCCGCCGAGACGCTGCCGCTGTATTTCTCCGCACTCGCCCGATCG
CGCGCCGACTGGCTGATCGGGATGAACCTGAGCCGCTTGTTCACACTGCTGGGGCGCCAGGCCGGCTATACCGGCGTGCT
GTCGGTGGGGCGCGTGCAGACGCCGACGCTGAAACTGGTGGTGGACCGCGATCGCGAGATCGCGCGCTTCGTCTCCGTGC
CGTATTGGGCCGCGGACGTGCTGCTATCCCATGCCGGCCAGTCCTTCACCGCGAGCTGGATACCGCCCGAAGGCAGCACC
GATGCAGCAGGTCGTTGCCTTCAGCAGCCGGTGGCGCAGCAGGCGGTGGATCGCATTCGCGCCGCACGCGATGCGCAGGT
CGTGTCGGTGGACACCGAGCGCGTGCGCGAGGCACCGCCGCTGCCGTTCGACCTGGGCACCTTGCAGGAAGTGTGTTCGC
GTCAGCTCGGCCTCGATGTGCAGGAGACGCTGGACATCGCGCAGGCGCTGTACGAGACGCACAAGGCGACGACCTATCCG
CGCAGCGACTCGGGATACCTGCCCGAAAGCATGCTCGCGGAAGTGCCGGCGGTGCTCGATGCACTGCTCGCCACCGAACC
CAGCCTGCGGCCCTTGCTCGGCCAGCTCGACCGCAACCAGCGTTCGCGCGCCTGGAACGACGGCAAGGTGACGGCGCACC
ACGGCATCATCCCCACGCTGGAGCCGGCCAAGCTCTTGGCCATGTCGGAGAAAGAACTGGCGGTCTACCAGCTGATCCGC
GGGCGCTATCTCGCGCAGTTTCTTCCACACCATGAGTTCGACCGCACGGTGACGCAGCTCGCTTGCGGCGGCCAGTCGCT
CGTGGCGGTGGGCAAGCAGATCGCCGTGATCGGCTGGCGCCAGGTACTGGCGACACCGGAGCCGGACGCTGCCGATGGCG
AGGAAGCGCAGCGCAGCCAGGTGCTGCCGCCACTGGCGAGCGGATCGCGCTGCGGGGTCGAGCAGGTCGAGCTGAAGGCG
CTGAGAACGCTGCCGCCGAAGCCCTACACCCAGGGCGAACTGGTCAAGGTGATGAAGGGCGTGGCCAAGCTAGTGGACGA
CCCGCGTCTGAAGCAGAAGCTGAAGGAGACGACGGGCATCGGCACCGAGGCCACGCGCGCCAGCACGATCAAGGGCCTGC
TCGATCGCGGCTACCTGCTGAAGAAGGGCCGCGCCATCCGCGCGTCGGATGCGGCCTTCACGCTCATCGACGCCGTGCCG
GCGGCCATCGCCGATCCCGGCATGACCGCCATCTGGGAGCAGGCGCTCGACATGATCGAGGCCGGCCAGATGACGCTGGA
CACCTTCATCGCCAAGCAATCCACCTGGGTGGCCCAGCTCGTGCAGCAGCATCGGGGCGCGACGCTTTCCATCGCGCTGC
CGCCGTCGCCGCCCTGCCCGCAGTGCGGCGCGCCGATGCGCCAGCGTACCGGCAAGAGCGGCGCGTTCTGGTCATGCAGC
CGTTATCCAGACTGCAAGGGCACGCTGCCGGTCGAATCCTCGGCAAGCAAGCGCGGTGCGCCACGCAAGCGGCGCACAGT
ACCCAAGGCGTCCTGA

Protein sequence :
MRVFLCEKPSQGKDIARVLGAGQRSNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWAIEQLPIVPERWRVEPKVATA
AQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARS
RADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAADVLLSHAGQSFTASWIPPEGST
DAAGRCLQQPVAQQAVDRIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSRQLGLDVQETLDIAQALYETHKATTYP
RSDSGYLPESMLAEVPAVLDALLATEPSLRPLLGQLDRNQRSRAWNDGKVTAHHGIIPTLEPAKLLAMSEKELAVYQLIR
GRYLAQFLPHHEFDRTVTQLACGGQSLVAVGKQIAVIGWRQVLATPEPDAADGEEAQRSQVLPPLASGSRCGVEQVELKA
LRTLPPKPYTQGELVKVMKGVAKLVDDPRLKQKLKETTGIGTEATRASTIKGLLDRGYLLKKGRAIRASDAAFTLIDAVP
AAIADPGMTAIWEQALDMIEAGQMTLDTFIAKQSTWVAQLVQQHRGATLSIALPPSPPCPQCGAPMRQRTGKSGAFWSCS
RYPDCKGTLPVESSASKRGAPRKRRTVPKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 79
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 77
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 63
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-164 52
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 2e-159 50
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 2e-159 50
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 1e-159 50
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 2e-162 49
topB AAW83109.1 TopB Not tested GGI Protein 2e-119 41