Gene Information

Name : Alide_0227 (Alide_0227)
Accession : YP_004124898.1
Strain : Alicycliphilus denitrificans BC
Genome accession: NC_014910
Putative virulence/resistance : Virulence
Product : heavy metal response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 254110 - 254796 bp
Length : 687 bp
Strand : +
Note : TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; KEGG: dia:Dtpsy_2215 two component heavy metal response transcriptional regulator, winged helix family; SMART: response regula

DNA sequence : 
ATGAAGCTGCTGATCGTGGAAGACGAAGCCAAGCTCGCGGACTATCTTCGCAAGGGACTCTCTGAAGAAGGCTATGTGAT
CGATGTGGCTGTCAACGGCATCGATGGCCTCCACATGGCCTCTGACGGCCACTACGACCTGATCGTTCTCGACACCATGC
TGCCGGGCATCGACGGCTTTGGCTTGCTGGCCGCGCTGCGACAGAACAAGCAGACGCCGGTGATCATGTTGACGGCCCGT
CATCGTATCGAGGATCGCGTGCGCGGACTGAAGACGGGAGCGGACGACTACCTCGTTAAGCCGTTCGCCTTTTCCGAACT
GGTGGCACGCATCGAGGTGCTGCTGCGCCGCGCTGCTGGTACTGCACCCGCGCCTGATGCGCTGGTGCTGTGCCTTGGGG
ATTTGCAAGTGGACCTGGCGAGGCGGCGCGCTACTCGGGCCGGCCAGCGCATCGACCTGTCCGCAAAGGAGTTCCAACTG
CTGACGCTGCTCTTGCGCCGCAAGGGCGAGGTTCTGTCACGTACCGAAATCGCGGAGCAAGTATGGGACGTGAACTTCGA
TCACGGTACCAACGTGATCGACGTCGCTGTGCGTCGCCTTCGGAGCAAGCTCGACCTGCCCTTCGAGCGCCCACTGCTGC
ACACCGTCCGTGGCATGGGCTACGTACTCGAAGATCGGCAGTCGTGA

Protein sequence : 
MKLLIVEDEAKLADYLRKGLSEEGYVIDVAVNGIDGLHMASDGHYDLIVLDTMLPGIDGFGLLAALRQNKQTPVIMLTAR
HRIEDRVRGLKTGADDYLVKPFAFSELVARIEVLLRRAAGTAPAPDALVLCLGDLQVDLARRRATRAGQRIDLSAKEFQL
LTLLLRRKGEVLSRTEIAEQVWDVNFDHGTNVIDVAVRRLRSKLDLPFERPLLHTVRGMGYVLEDRQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-55 52
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-54 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Alide_0227 YP_004124898.1 heavy metal response regulator BAC0125 Protein 2e-61 58
Alide_0227 YP_004124898.1 heavy metal response regulator BAC0083 Protein 3e-58 57
Alide_0227 YP_004124898.1 heavy metal response regulator BAC0197 Protein 1e-61 57
Alide_0227 YP_004124898.1 heavy metal response regulator BAC0111 Protein 7e-59 57
Alide_0227 YP_004124898.1 heavy metal response regulator BAC0308 Protein 2e-56 56
Alide_0227 YP_004124898.1 heavy metal response regulator BAC0638 Protein 2e-52 56
Alide_0227 YP_004124898.1 heavy metal response regulator BAC0347 Protein 1e-50 51
Alide_0227 YP_004124898.1 heavy metal response regulator HE999704.1.gene1528. Protein 6e-33 44
Alide_0227 YP_004124898.1 heavy metal response regulator NC_007793.3914065.p0 Protein 2e-37 43
Alide_0227 YP_004124898.1 heavy metal response regulator NC_002758.1121390.p0 Protein 2e-37 43
Alide_0227 YP_004124898.1 heavy metal response regulator NC_010079.5776364.p0 Protein 2e-37 43
Alide_0227 YP_004124898.1 heavy metal response regulator NC_002952.2859858.p0 Protein 2e-37 43
Alide_0227 YP_004124898.1 heavy metal response regulator NC_007622.3794948.p0 Protein 2e-37 43
Alide_0227 YP_004124898.1 heavy metal response regulator NC_003923.1003417.p0 Protein 2e-37 43
Alide_0227 YP_004124898.1 heavy metal response regulator NC_013450.8614146.p0 Protein 2e-37 43
Alide_0227 YP_004124898.1 heavy metal response regulator NC_002951.3238224.p0 Protein 2e-37 43
Alide_0227 YP_004124898.1 heavy metal response regulator AE015929.1.gene1106. Protein 2e-32 41
Alide_0227 YP_004124898.1 heavy metal response regulator NC_002516.2.879194.p Protein 3e-33 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Alide_0227 YP_004124898.1 heavy metal response regulator VFG0596 Protein 8e-56 52
Alide_0227 YP_004124898.1 heavy metal response regulator VFG1389 Protein 3e-40 45
Alide_0227 YP_004124898.1 heavy metal response regulator VFG0473 Protein 3e-32 41