Gene Information

Name : Alide_1826 (Alide_1826)
Accession : YP_004126461.1
Strain : Alicycliphilus denitrificans BC
Genome accession: NC_014910
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1886172 - 1887860 bp
Length : 1689 bp
Strand : -
Note : KEGG: ajs:Ajs_1298 mercuric reductase; TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Heavy metal transport/detoxification protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region

DNA sequence :
ATGGCCGAAGCGATTGCTTTTCACATCGATGGAATGACCTGCGTGTCGTGCGCCGAGCACGTCAGGCAGGCTTTGGAGAA
CGTGTCCGGCGTGCGCACGGCCTCGGTGTCCTATCCGCATCGTCGGGCCGAGATCGAGGCGGATGCGGGCGTGAGCCTGG
ACCCGCTGGTTGCGGCGGTGACTGCGCTCGGCTACCGCGCACGGTTTTCCGATACGCCAAACAAGCCCGCCGGCCTGTTG
GACAAGGCGCTGGGCCGGCTCGGAGGCGAAACAAGGCGCGGTGGCGGCGAGCCGGCGCTGCACGTGGCCGTCATCGGCAG
CGGCGGCGCGGCGATGGCTGCGGCATTGAAGGCCGTGGAGCTTGGGACGCGCGTGACGCTGATCGAGCGCGGAACCATCG
GCGGCACCTGCGTCAACGTCGGATGCGTGCCGTCCAAGATCATGATTCGCGCCGCGCACATCGCGCATCTACGCCGCGGA
AGCCCGTTCGATTCTGGGCTCCCGCCTACGCCACCGTCTATCCTGCGCGAACGGCTGCTGGCCCAGCAACAAGGCCGCGT
CGAGGAACTGCGCCACGCCAAGTACGAAGGCATTCTGGAGAGTACTCCGGCGATCAACGTGCTACGCGGCGAGGCCCGGT
TCAAGGACGCGCGCACGCTGGCCGTGGCGACCGCTGACGGCGGCAAGCGCGAGGTGAGCTTCGACCGCTGCCTGATCGCC
ACCGGGGCGAGTCCGGCGATACCGCCGATCCCGGGCCTTGCGGACACGTCATACTGGACCTCCACCGAGGCGCTAGTGAG
CGACTCAATCCCTGAGCGGCTGGCCGTCATCGGCTCGTCGGTGGTCGCTGTCGAGCTGGCGCAAGCCTTCGCCCGGCTGG
GCAGTCATATCACGATCCTGGCGCGCAACGCACTGTTCTTCCGCGAAGACCCGGCCATTGGCGAGGCCGTCACGGCCGCC
TTCAGCGCCGAAGGCATCGAGGTACTGGATCACACCCAAGCCAGCCAGGTTGCCTATGCGGACGGTGAATTCGTACTCAC
GACTGGGCACGGCGAACTGCGCGCCGACAAGCTGCTGGTCGCCACCGGCCGAGCGCCGAACACGCGCAGCCTGAACCTCG
CGGCGGCGGGCGTCGAGGTCAACGCGCAAGGGGCCATCGTCATCGACCGCGCCATGCGCACCAGCGCGTCGCACATCTTT
GCTGCCGGCGACTGCACCGACCAGCCGCAATTCGTCTACGTAGCGGCGGCGGCCGGCACCCGTGCCGCGATCAACATGAC
CGGCGGTGACGCGGCGCTGGACCTGACGGCGATGCCGACAGTGGTGTTCACCGATCCGCAGGTGGCGACGGTGGGCTACA
GCGAAGCCGAAGCGCACCACGACGGCATCGAAACCGACAGCCGGCTGCTAACGCTGGACAACGTGCCAAGGGCGCTCGCC
AACTTCGACACGCGTGGCTTCATCAAGCTGGTCGCCGAGGCCGTCTCGGAACGGTTGATCGGAGTGCAGGCGGTCGCACC
CGAAGCGGGCGAGCTGATCCAGACGGCCGCGCTGGCGATCCGTCACCGGATGACCGTGCAAGAGCTGGCCGACCAGTTGT
TCCCGTATCTGACGATGGTCGAGGGGCTGAAGCTCGCGGCGCAAACTTTCAACAAGGACGTGAAGCAACTTTCCTGCTGC
GCCGGGTAA

Protein sequence :
MAEAIAFHIDGMTCVSCAEHVRQALENVSGVRTASVSYPHRRAEIEADAGVSLDPLVAAVTALGYRARFSDTPNKPAGLL
DKALGRLGGETRRGGGEPALHVAVIGSGGAAMAAALKAVELGTRVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRG
SPFDSGLPPTPPSILRERLLAQQQGRVEELRHAKYEGILESTPAINVLRGEARFKDARTLAVATADGGKREVSFDRCLIA
TGASPAIPPIPGLADTSYWTSTEALVSDSIPERLAVIGSSVVAVELAQAFARLGSHITILARNALFFREDPAIGEAVTAA
FSAEGIEVLDHTQASQVAYADGEFVLTTGHGELRADKLLVATGRAPNTRSLNLAAAGVEVNAQGAIVIDRAMRTSASHIF
AAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPTVVFTDPQVATVGYSEAEAHHDGIETDSRLLTLDNVPRALA
NFDTRGFIKLVAEAVSERLIGVQAVAPEAGELIQTAALAIRHRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCC
AG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 90
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 80
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 80
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 79
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 79
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 79
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 78
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 78
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 78
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 76
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 3e-86 41
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-86 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Alide_1826 YP_004126461.1 mercuric reductase BAC0653 Protein 0.0 81
Alide_1826 YP_004126461.1 mercuric reductase BAC0652 Protein 0.0 78
Alide_1826 YP_004126461.1 mercuric reductase BAC0650 Protein 8e-176 70
Alide_1826 YP_004126461.1 mercuric reductase BAC0651 Protein 1e-86 41
Alide_1826 YP_004126461.1 mercuric reductase BAC0224 Protein 2e-85 41