Gene Information

Name : Pat9b_4768 (Pat9b_4768)
Accession : YP_004118657.1
Strain :
Genome accession: NC_014839
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 57613 - 59217 bp
Length : 1605 bp
Strand : -
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: sen:SACE_2694 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGTCTGAACCGATTGCGAACCCCGATCATCGCATCCTGCCACAGGAGATGCGCTGGCCGGTTGCACTGGCTGAACGTTA
TACGCAACGCGGCTACTGGCAGCCGGAAACCCTCGGACAGCTGATTCTGCAATGGCGGCAGTATGGTGAACGTACTGCTC
TGATCGAACCGGGCCGCAGCTGGAGTTATCAACAGTTGATCACTCAGGCTCGTCGCTTCGCCAGTGACCTCAGGCAGCGA
GGGATGCGCAGCGGAGAAACGGTGGTTATCCAGTTGCCTAACGGTGCCGATTTTGTGGTGGCCTTGTTCGCGGTGATCCT
TAACGGAGCGGTGCCCGTGCTGATGTTACCCGCCCATCGCCAGCGTGAAATCCTGCACGTGGTGGAGCTGGCACAGGCGC
GCTGGTTCCTGAGTGACGCCGAACAGACGGGCATCGACGCTCAGACTCTGCGTAATAACGCCCCTGATTGTCATCGCCTG
TTTTCCATCGCAGGCGAGCGTTTTGCCGCCAGCCAGGCTCCGGCGATTGACGGGTTGCCGCCCGGCGATGCGGCCCAACA
TATCGCTTTGCTGCTGCTTTCAGGCGGCACTACCGGGTTACCCAAGCTGATCCCACGCACCCACGCCGATTATCACTACA
ACTTTCGCGCCAGCGCCGCGCTTTGCCATGTGCTGCCGGATGACTGTTATATGGCGGTGCTTTCGATGGCACATAACTTT
CCCCTCGCCTGTCCGGGCATCCTCGGCATCTTTTCCCGTGGTGGTTGTGTGGTAGTCCCGGCCACGGCGGCTGCGGAGGA
TGCGTTTGACGCGATTCGTCAGCACCGCGTGACGCTGACGGCGCTGGTGCCTTCTCTGGCAACGCTATGGCTGGAAGCGG
CGGAATGGGAACAACCGGATCTCAGCTCGCTGAGGCTGGTCCAGGTGGGTGGTGCCAGGTTGGGAGCCGATGCTGCTCGC
CAGTTGCTGGCCCAGTGGGGATGCCAGTTGCAACAGGTGTTTGGCATGGCGGAAGGGTTACTGAACTACACGCGGCTGGA
TGATTCGCCCGAACGGATAACCACCACGCAGGGCCGACCATTGTGTGACGACGATGAGATCCGGGTGGTGGACGAGCAGG
GCCAAGCCGTGGTCACAGGGCAGGCGGGGGAATTGCTGGTTCGCGGGCCTTACACCATCCGTGGTTACTATCGTGCGCCT
GAACACAATCGGCAGGCGTTTGCCTCTGAGGGATTTTACCGCAGCGGCGATCGGGTGCGGCAGTTGCCTGGCGGTGAACT
GCTGGTGGAGGGACGCACGCGCGACATGATCAACCGCCACGGGGAATCGGTCGCCGCCGATGAAATCGAGGAATGTCTGC
GGGCGCATCCGCTGGTGCGTGACGTGACGGTACTGGCAGATGCAGACGGAGAGCAACAGGAAGCGATCCATGCGGTGGTC
ATCGCCCATACCCCTTTCACGCTGGCCGAACTGCGGGCATTCCTTGAGCAGCAACAAGTCGCGTCATTTAAATGGCCGGA
TCGACTGACACTGGTGGATGCTTTCCCGCTCACACCGATTGGCAAAATCAATAAACACGTGCTGGCCACCCGGCTGGCGG
TTTAA

Protein sequence : 
MSEPIANPDHRILPQEMRWPVALAERYTQRGYWQPETLGQLILQWRQYGERTALIEPGRSWSYQQLITQARRFASDLRQR
GMRSGETVVIQLPNGADFVVALFAVILNGAVPVLMLPAHRQREILHVVELAQARWFLSDAEQTGIDAQTLRNNAPDCHRL
FSIAGERFAASQAPAIDGLPPGDAAQHIALLLLSGGTTGLPKLIPRTHADYHYNFRASAALCHVLPDDCYMAVLSMAHNF
PLACPGILGIFSRGGCVVVPATAAAEDAFDAIRQHRVTLTALVPSLATLWLEAAEWEQPDLSSLRLVQVGGARLGADAAR
QLLAQWGCQLQQVFGMAEGLLNYTRLDDSPERITTTQGRPLCDDDEIRVVDEQGQAVVTGQAGELLVRGPYTIRGYYRAP
EHNRQAFASEGFYRSGDRVRQLPGGELLVEGRTRDMINRHGESVAADEIEECLRAHPLVRDVTVLADADGEQQEAIHAVV
IAHTPFTLAELRAFLEQQQVASFKWPDRLTLVDAFPLTPIGKINKHVLATRLAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-90 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 47
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-90 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 47
ybtE CAA21394.1 - Virulence HPI Protein 3e-90 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-90 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-90 46
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 7e-90 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Pat9b_4768 YP_004118657.1 AMP-dependent synthetase and ligase VFG0168 Protein 9e-97 49
Pat9b_4768 YP_004118657.1 AMP-dependent synthetase and ligase VFG1817 Protein 3e-87 44
Pat9b_4768 YP_004118657.1 AMP-dependent synthetase and ligase VFG0932 Protein 4e-86 42