Gene Information

Name : Rumal_0869 (Rumal_0869)
Accession : YP_004104030.1
Strain : Ruminococcus albus 7
Genome accession: NC_014833
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 969057 - 970634 bp
Length : 1578 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: dae:Dtox_2676 AMP-dependent synthetase and ligase

DNA sequence :
ATGGTTAAAGATTATGAAGCAGCAGGCTATTGGGAAAAGAAGACCCTCTGGGACAGACTTGAGGAGTGGAAAAACAGCTA
TGCAGATAGATGTGCATTGGTGGATGAAGATATCCGTATCAGCTATCAGCAATTGTATGACCACGCACTGCAGTATGCTG
CAGCATTTGCGGCAGACGGTATACACGAAGGAGATACTGTTGCGGTACAGCTTCCTAATTGCGCAGCGTTTGTGGAAATG
GTGTTCGGCTTGTTCCGGATAGGTGCAGTTCCTATCTTTGTTTTGCCGGCGCACCGTGAAAAAGAGATAACAGGTATTTT
TAATGCGGCTTCTCCGAAGGCATACATAACTGCGAGAACTTTTTTGGGCTTTGATTATACAGCTATGGCAGAACGAATCC
TGAAAGAGCGTTCTGATCAGCAGATAAGATACTATGTTGCGGATGAACTGCAAAACACAGCAAAGCTCGCTGATGTGACA
ACACTTTCCTCTGACGGACCTTGCTACAGGGATACAGCATTTCTGCTGTTATCAGGTGGAACAACAAATACCCCTAAACT
GATCCCCAGGACGCATTGTGACTATGCGTATAATTTCCGTATGGCTGCAGAGAAAAGCTGGCTGGATTCGGACAGTGTCT
ATCTGGTGACACTTCCGATCGAGCATAATTTCCCGTGGGGAATGCCGGGTGTACTGGGAACCCTTTCTGTAGGCGGCAAA
GTAGTTATCGCCAAAACATCGAGCTTTGACGAAGTTTTTCCGCTGATAGAGGAGGAGAAGGTAACTATCACCGCAGCTGT
ACCGGCTGTCCTTCAGACCTGGCTGGAAGCACTGGAATGGGAAGATTCCTATGATCTGGGATCGCTGCGACTGATCCAGG
TGGGAGGTGCAAAGCTTCTCGATTCGATAGCAAGAAAAGTCAGACCTGCTTTTAATTGTACCTTACAGCAGGTGTTTGGC
ATCGCTGAGGGGCTGATCACTTTTACATCTCCCGATGATACGGAGGATATAATCACCACCTGCCAGGGCAAACCGTTGAG
TGAAGGCGATGAGATACGAATTGTTGATGAGCAGGAGCAGGATGTTGAAGATGGTGAATTCGGACAGCTTCTTATGAAAG
GGCCTTACACTATACGCGGCTATTACGGATGCCCTGAATTCCAATCGGATATTTTTACTGAGGACGGATTTTTCCGTACA
GGTGACAAGGCGTGTATCACTAAAGAAGGGAACCTGCTGGTGGACGGTCGTATTACTGATCAGATCAACCGCGGAGGAGA
AAAGGTAATGCCCACGGAGATCGAGGAACTTCTGCTGGAGCATGAAGCTGTACAGGAAGCGATCGTTGTCCCTGTCCCTG
ACGAACAGTTCGGTCAGAAAAGCTTTGCTTTTCTGAAATGCAGCCGTGAAGTATCTTTTGCAGAGGTGTATGAATTTTTA
AAGTCCAGAAGACTTGCAAGATACAAATATCCTGACTATATCCGCTTTTTGGACAGGATACCTCTTACCAATATGGGAAA
AACCAATCGCGCAGAATTAAAGAAAATGGCAGTGGAGGACATAAATGAAAGAACTTGA

Protein sequence :
MVKDYEAAGYWEKKTLWDRLEEWKNSYADRCALVDEDIRISYQQLYDHALQYAAAFAADGIHEGDTVAVQLPNCAAFVEM
VFGLFRIGAVPIFVLPAHREKEITGIFNAASPKAYITARTFLGFDYTAMAERILKERSDQQIRYYVADELQNTAKLADVT
TLSSDGPCYRDTAFLLLSGGTTNTPKLIPRTHCDYAYNFRMAAEKSWLDSDSVYLVTLPIEHNFPWGMPGVLGTLSVGGK
VVIAKTSSFDEVFPLIEEEKVTITAAVPAVLQTWLEALEWEDSYDLGSLRLIQVGGAKLLDSIARKVRPAFNCTLQQVFG
IAEGLITFTSPDDTEDIITTCQGKPLSEGDEIRIVDEQEQDVEDGEFGQLLMKGPYTIRGYYGCPEFQSDIFTEDGFFRT
GDKACITKEGNLLVDGRITDQINRGGEKVMPTEIEELLLEHEAVQEAIVVPVPDEQFGQKSFAFLKCSREVSFAEVYEFL
KSRRLARYKYPDYIRFLDRIPLTNMGKTNRAELKKMAVEDINERT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-91 44
ybtE CAA21394.1 - Virulence HPI Protein 2e-91 44
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-91 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-91 44
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-91 44
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-91 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-91 44
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-91 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-91 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rumal_0869 YP_004104030.1 AMP-dependent synthetase and ligase VFG0168 Protein 4e-89 42