Gene Information

Name : Tmar_1819 (Tmar_1819)
Accession : YP_004102647.1
Strain : Thermaerobacter marianensis DSM 12885
Genome accession: NC_014831
Putative virulence/resistance : Unknown
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.60
Position : 2176923 - 2178554 bp
Length : 1632 bp
Strand : -
Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR011985: IPR016160: IPR015590; KEGG: aac:Aaci_0338 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: 5-carboxymethyl-2-hydroxymuconate semialdeh

DNA sequence :
ATGGACGGAGGAACCCAGCCGGAGGCGGCGGCCGCAGCGGCCGGGCCCGCCGGTGCGAGGAAGGCGGTGCCGGGAGCGGC
TGCAGGGACGGCTGCGGGGACGGTTGCGGGGACGGTGTCGGAAGCGGCGGGCGGTCCGGAGCCGGCCGTGCCCCGGCAGG
TGCTGCACTACATCGGCGGCCGGTTCGTCCCGCCCCGGTCGGGCCGGTTCTTCTCCACCCTGAACCCGGCCACCAACCGC
CCCCTGGCGGAGGTGGCGGAGGGGAGCCCGCACGACGTGGACGCGGCAGTCCAGGCCGCCCGAAAGGCCTTCGACGAGGG
ACCGTGGCCGCGGATGCTGCCCGCCGAGCGGGCCCGGTACCTGGAGCGGATCGCGGAGCGCATCGAGGCGCAGGGGGAGG
CCATCGCCCGGGTCGAGGTGATGGACACGGGCATGCCCATCAGCCAGGCCCGGGGCCAGGCGGCCCGGGCGGCGGAGAAC
TTCCGCTTCTTCGCCCGGCGGATCCAGGACCTGGGCGGCCAATCCTGGCCGGTGGGGGGCCGGTTCGTCAACTACGTGAT
CCACAAGCCCGTGGGCGTGGCGGGGCTCATCACCCCGTGGAACACGCCCTTCATGCTGGCGACCTGGAAGGTGGCCCCCT
GCCTGGCGGCGGGGAACACCTGCGTGCTCAAGCCCGCCGAATGGGCGCCCCTCTCGGCCCACCTGCTGGCGGAGATCGTG
GCCGAGGCGGGGCTCCCCGAAGGCGTTTTCAACGTGGTCCACGGTTTCGGCGAGCCGGCCGGGGCCGGCTTGGTGGCCCA
TCCGGCGGTGAACCTGATCTCCTTCACCGGCGAGACTACGACGGGGAAGGCCATCATGGCCAACGGCGCCGCCACCCTCA
AGCGGTACTCCTTCGAGCTGGGCGGCAAGTCGCCAGTGGTGATCTTCGCCGACGCGGACCTCGAGCGGGCGGTGGACGCC
GCGGTGTTCGGGGTCTTCTCCCTCAACGGCGAGCGGTGCACGGCGGGGTCGCGGCTTCTGGTGGAAGAACCGGTCTACCG
CGACGTGGTGGAGGCCGTGGCCCGGCGGGCGGCGCGGATCCGCATCGGCGACCCGGCCGATCCCGGCACGGAGCTGGGGC
CGCTGATCCACCCCGAGCACTGGCGGCGGGTGATGGGCTACGTGGAAGCCGGGCGGGCCGAGGGGGCGGAGCTCGTGACC
GGCGGGCGGCGGCCAACGGGGCTCCCGCCGGAGCTCGCGGGGGGCAACTACCTCGAGGCGACGGTCTTCGCCGGCGCCCG
GCCCGAGATGAAGGTGTTCCAGGAAGAGATCTTCGGGCCGGTGGTGGTGGCGACGCCCTTCCGCACCGAGGAGGAGGCGG
TCCGCCTGGCCAACGCCGTGCGCTACGGGCTGGCGGCTTACGTCTGGACCCGGGACGTAGGGCGGGGCCACCGGGTCGGG
CACGCCATCGACGCCGGCATGGTCTGGCTCAATTCGCAGAACGTGCGCGATCTGCGGACGCCCTTCGGCGGCATGAAGGA
GAGCGGCATCGGCCGGGAGGGCGGCGACTACAGCTTCGAGTTCTACTGCGAGCGGCAGGTCATCCACGTGGCGCTGGGGG
AGCACCCGATCCCGCGCTTCGGTACGGGATGA

Protein sequence :
MDGGTQPEAAAAAAGPAGARKAVPGAAAGTAAGTVAGTVSEAAGGPEPAVPRQVLHYIGGRFVPPRSGRFFSTLNPATNR
PLAEVAEGSPHDVDAAVQAARKAFDEGPWPRMLPAERARYLERIAERIEAQGEAIARVEVMDTGMPISQARGQAARAAEN
FRFFARRIQDLGGQSWPVGGRFVNYVIHKPVGVAGLITPWNTPFMLATWKVAPCLAAGNTCVLKPAEWAPLSAHLLAEIV
AEAGLPEGVFNVVHGFGEPAGAGLVAHPAVNLISFTGETTTGKAIMANGAATLKRYSFELGGKSPVVIFADADLERAVDA
AVFGVFSLNGERCTAGSRLLVEEPVYRDVVEAVARRAARIRIGDPADPGTELGPLIHPEHWRRVMGYVEAGRAEGAELVT
GGRRPTGLPPELAGGNYLEATVFAGARPEMKVFQEEIFGPVVVATPFRTEEEAVRLANAVRYGLAAYVWTRDVGRGHRVG
HAIDAGMVWLNSQNVRDLRTPFGGMKESGIGREGGDYSFEFYCERQVIHVALGEHPIPRFGTG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-110 51
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 8e-62 42
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-69 42