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Name : Tmar_1608 (Tmar_1608) Accession : YP_004102444.1 Strain : Thermaerobacter marianensis DSM 12885 Genome accession: NC_014831 Putative virulence/resistance : Resistance Product : mercuric reductase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : 1.16.1.1 Position : 1936903 - 1938654 bp Length : 1752 bp Strand : + Note : COGs: COG1249 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR000815: IPR013027: IPR006121: IPR011796: IPR 012999: IPR017969: IPR004099: IPR021179; KEGG: gka:GK3096 mercuric reductase; PFAM: FAD-dependent pyr DNA sequence : TTGTCAACCTTGAAGCCGGGTCGCTATCATCTCGCGATCGAGGGCATGACCTGTGCACACTGCGCGACCACCGTGCAGCT GGCTTTGGAACAGGCCGGAGCGCGGGCGGTAGAAGCCGACTTCCGGCGCGGTGTGGCGGTGTTCGACCTGCCGCAACCCG CCGATCCCGAGGACCTGCGGGCCGCCGTACGGGGGGCCGGTTACCAGCCCGGGGCCTTGGCACGGCTGGAACCGGGCGAC GGTTGCTCCCAGGCGGCCCCAGCCCCTCAGGCTGTTCGGGCCGCTCAGTCGTCCCCCGCCCCTCATGCCTCTCCCGCCTC CAAAGCAACACCCCGCCAACCCTATGATCTGGTGATCGTTGGTTCAGGGTCGGCTGCTTTCGCCGCCGCCATCGAGGCGA GCCAGGGGGGTGCCCGGGTGGCCATGGTCGAGCGGGGCGTGGTGGGGGGCACCTGTGTCAACATCGGCTGCGTGCCGTCG AAGACGCTGCTGCGGGCCGCCGAGATCTACTTCCGCACTCGCCACCACCCTTTCGCCGGCATCGCCACCCAGGCGGGGCC GGTGGACCTACCGCTGCTCATCGGCCAGAAGAACGAGCTGGTTTCGCGGCTGCGGTACCAGAAGTACGAGCGCCTGGTTG ATACGTACGGCTTCGACCTGCTGCGCGGCGAGGGGCGGTTCCTCGATGCCCATACCCTGCAGGTAGTCGACCCGCAGAAC GGTGAGGTGAGCCGGACGCTCGAGGCCCGGGCGTTCCTCATCGCGACCGGCGCCGCCCCGGCCGTCCCCGACGTGCCGGG GCTCGAGGCCGTCGACTTCCTGACCAGTACCTCGGCCCTCGACCTGCGGCGGCTGCCCGAGAGCGTGGCCGTCATCGGCG CGGGGTACATCGCCCTGGAGCTGGGCCAGTTCTTCCGGCACCTGGGGGCCCAGGTGACCATCATGCAGCGCAGCCCCGAG CTGCTGAAGGCGTATGACCCTGAGATTCGAGACGCCGTTCGCCGCATGCTGGACGAACACGGCATCGAGGTGCTGACAGG GGTTCGCTACCTCGGGGTCGACCAGGCGGGCGGGCTCAAGCGGGTGCGGCTTGAGGTCGCGGGGGTCGAACGGGCCGTCG AGGCGGAGGCCCTGCTGGTTGCGACGGGCCGGCGCCCCAATACCGCGGCGCTACAGCTCGACAGGGCCGGCGTCCGTACG GGACTCCGCGGCGAGGTTGTGGTCGACGAGCAGCTGCGGACCAGCGTCCCCCACATCTTCGCGGCCGGCGACGTGACCAT GGGGCCCCAGTTCGTCTATGTGGCCGCCTACCAGGGCGCCCTGGCCGCCCGCAACGCCGTCTGTGGAGCAGAGGAGCGGG TCGATCTGCGTGCCGTCCCGCGGGTGACCTTCACCACCCCGGCCATCGCTAGCGTGGGTCTGACGGAGGAGCAGGCCCGG GCCGCCGGCCACCGGGTACGGGCCTCCGTCCTCCCCCTGGAGACGGTGCCACGGGCCCTGGCTAATCGCGAGACCACCGG GGTGTACAAGTTGGTCGCCGACGCCGACACAGGCCGGTTGCTGGGGGCCCACGTGGTGGCAGAGAATGCTGGCGATGTGA TCTACGCCGCTACCCTGGCCGTCAAGTTCGGGCTGACGATCGAAGACCTGCGGTCCACCCTGGCACCATACCTGACCATG GCCGAGGGACTGAAGCTTGCGGCACTGGGTTTCAAGACCGAGGTCTCCAACCTCTCCTGTTGCGCGGGGTAG Protein sequence : MSTLKPGRYHLAIEGMTCAHCATTVQLALEQAGARAVEADFRRGVAVFDLPQPADPEDLRAAVRGAGYQPGALARLEPGD GCSQAAPAPQAVRAAQSSPAPHASPASKATPRQPYDLVIVGSGSAAFAAAIEASQGGARVAMVERGVVGGTCVNIGCVPS KTLLRAAEIYFRTRHHPFAGIATQAGPVDLPLLIGQKNELVSRLRYQKYERLVDTYGFDLLRGEGRFLDAHTLQVVDPQN GEVSRTLEARAFLIATGAAPAVPDVPGLEAVDFLTSTSALDLRRLPESVAVIGAGYIALELGQFFRHLGAQVTIMQRSPE LLKAYDPEIRDAVRRMLDEHGIEVLTGVRYLGVDQAGGLKRVRLEVAGVERAVEAEALLVATGRRPNTAALQLDRAGVRT GLRGEVVVDEQLRTSVPHIFAAGDVTMGPQFVYVAAYQGALAARNAVCGAEERVDLRAVPRVTFTTPAIASVGLTEEQAR AAGHRVRASVLPLETVPRALANRETTGVYKLVADADTGRLLGAHVVAENAGDVIYAATLAVKFGLTIEDLRSTLAPYLTM AEGLKLAALGFKTEVSNLSCCAG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 4e-140 | 55 |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 3e-140 | 55 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 2e-70 | 45 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 1e-70 | 45 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 1e-70 | 45 |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 6e-71 | 45 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 6e-71 | 45 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 6e-71 | 45 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 1e-74 | 44 |
| unnamed | ABR13401.1 | mercuric reductase | Not tested | PAGI-5 | Protein | 6e-72 | 44 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 1e-74 | 41 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 6e-75 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tmar_1608 | YP_004102444.1 | mercuric reductase | BAC0651 | Protein | 2e-140 | 55 |
| Tmar_1608 | YP_004102444.1 | mercuric reductase | BAC0224 | Protein | 1e-142 | 54 |
| Tmar_1608 | YP_004102444.1 | mercuric reductase | BAC0650 | Protein | 5e-71 | 43 |
| Tmar_1608 | YP_004102444.1 | mercuric reductase | BAC0653 | Protein | 2e-72 | 42 |
| Tmar_1608 | YP_004102444.1 | mercuric reductase | BAC0652 | Protein | 9e-75 | 41 |
