Gene Information

Name : Tmar_1513 (Tmar_1513)
Accession : YP_004102351.1
Strain : Thermaerobacter marianensis DSM 12885
Genome accession: NC_014831
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 1820012 - 1821670 bp
Length : 1659 bp
Strand : -
Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: bts:Btus_1063 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase family

DNA sequence :
ATGACGGTGTGGGATGAAGGGGGGGCAGTGCCGCCTGGCGGCGGCACCGCCGCCGAGGCAGCGCCCGCGGCGGAGCCGAC
GGCGGCAGGGGCCGCCGCGGCGGGGAAGGCGGTGGAAGCTGCGGCTGGACCGGGGACCGGGGGCCCGGGTTCCCCCCTCA
CCCGCACCCGCACCCTGAAGCTTCCTTTCGTGGCGCCGGTCGTGCGCCAGTGGCTCGGGTCCCGCAAGCTGCTCTTCATC
GGTGGGCGCTGGCAGGAGCCGCGGTCGGGTCGCTACCTGGTGGTGACGGACCCGGCCACCGGGGAGCCCCTGGCGGAGGT
GGCCGAGGCCGGGGAGGAGGACGTCGACCTAGCCGTCAAGGCGGCCCGGCGGGCCCTGGAGGGCACCTGGGGCAAGCTAC
CCCCGGCGGAGCGGGGTCGGCTGCTCTGGAAGCTGGCCGACCTCCTGGAAGAGAACGCCCAGGAGTTCGCCCAGTTGGAG
TCCCTCAACACCGGCAAGCCGGTCACGGAGACCACCATGGCCGACGTGCCCCTAGCCGTCGAGCACTTCCGCTACTTCGC
CGGCTGGGCGACCAAGTGGACGGGCGAGACCCTGCCCGCGTCCTTCCCCGGCGAGTACCTGGCCTACACCCGGCGGGAGC
CGGTGGGGGTGGTGGGGGCCATCGTCCCCTGGAACTTCCCCCTGATGATCGCCTCCTGGAAGCTGGCGCCGGCCCTGGCC
ACGGGGAACACGGTGGTGCTCAAGCCCAGCGAGCTCACTCCCCTGACGGCCCTGCGGCTGGCCGAGCTGGTGCGGCAGGC
GGGCTTCCCGCCGGGCACGGTGAACGTGGTGCCCGGCTACGGTGAGCCGGCGGGCCGCGCCCTGGTCGACCATCCCGGCG
TAGACAAGATCTCCTTCACCGGTTCGCCGGGGGTCGGCCGCAAGATCATGACGGCGGCGGCCCGGGACTTCAAGCGGGTG
ACCCTGGAGCTGGGGGGCAAGTCGCCCAACATCGTCTTCCCCGACGCCGACCTCGACAACGCCGTGGCGGGGGCGATGAT
GGGGATCTTCTTCAACCAGGGCGAGGTCTGCTGTGCCGGATCCCGCCTGTTCGTCCACAAGGAGCACTTCGACCGGATAG
TCCAGGACATCGCCGACCGGGCAAGCCGGCTGCGCCAGGGGCCCGGCATCCACCCCATGACGCAGATGGGACCGCTGATC
AGCCGCAGCCACTTGGAGCGGGTGCTGAGTTACATCGAGCGTGGTCGGGAGGAAGGGGCCGAGCTCCTGGTGGGGGGCGA
GCCCAACTCCGAGGCGGGGCCGGGCTACTTCGTCAAGCCCACCGTCTTCGTCGGCCGGGACGACATGACCATCGCCCGGG
AGGAGATCTTCGGTCCGGTGCTGACGGTGCTGCCCTTCGAGAGCCTGGACGAGGTGGTGCGGCGGGCCAACGACACCCCG
TACGGCCTGGCGGCGGGGATCTGGACGCGGGACGTGGCTAAGGCCATCAAGGTGGCCCACCGCCTGAAGGCCGGGACGGT
GTGGATCAACGGCTACAACCTGCTGGACGCCACCAGCCCGTGGGGCGGGTTCAAGCAGAGCGGCATCGGGCGGGAGATGG
GGCGGTACGCGCTGGAACACTACACGGAGGTCAAGAGCGTCTGGGTCAATCTGGGATGA

Protein sequence :
MTVWDEGGAVPPGGGTAAEAAPAAEPTAAGAAAAGKAVEAAAGPGTGGPGSPLTRTRTLKLPFVAPVVRQWLGSRKLLFI
GGRWQEPRSGRYLVVTDPATGEPLAEVAEAGEEDVDLAVKAARRALEGTWGKLPPAERGRLLWKLADLLEENAQEFAQLE
SLNTGKPVTETTMADVPLAVEHFRYFAGWATKWTGETLPASFPGEYLAYTRREPVGVVGAIVPWNFPLMIASWKLAPALA
TGNTVVLKPSELTPLTALRLAELVRQAGFPPGTVNVVPGYGEPAGRALVDHPGVDKISFTGSPGVGRKIMTAAARDFKRV
TLELGGKSPNIVFPDADLDNAVAGAMMGIFFNQGEVCCAGSRLFVHKEHFDRIVQDIADRASRLRQGPGIHPMTQMGPLI
SRSHLERVLSYIERGREEGAELLVGGEPNSEAGPGYFVKPTVFVGRDDMTIAREEIFGPVLTVLPFESLDEVVRRANDTP
YGLAAGIWTRDVAKAIKVAHRLKAGTVWINGYNLLDATSPWGGFKQSGIGREMGRYALEHYTEVKSVWVNLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 6e-86 47
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-84 45
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-93 45
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-96 45
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-96 45
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-96 45
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-96 45
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 4e-84 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmar_1513 YP_004102351.1 aldehyde dehydrogenase VFG0082 Protein 6e-94 45