Gene Information

Name : Tmar_0981 (Tmar_0981)
Accession : YP_004101821.1
Strain : Thermaerobacter marianensis DSM 12885
Genome accession: NC_014831
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 1193671 - 1195059 bp
Length : 1389 bp
Strand : +
Note : COGs: COG1157 flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR003593: IPR005714: IPR020003: IPR004100: IPR 000194; KEGG: hmo:HM1_2224 flagellar protein export ATPase FliI, PFAM: H+transporting two-sector ATPase alpha/subunit beta cen

DNA sequence :
ATGGCCGTGACCGCGGCGGACCTGCAGGCGGCAGCCCCGCGCATGGACGAAGCGCTTCCGGACGGCCCGGACTCCCTCCT
GGACTGGTCGCGGCTGCAGGCGGCGCTGGAAACCGCCGACCCCCGGCCGACCCAGGGCTGGGTCGAGCAGGTGGTGGGCC
TGGCGGTGGAGGCCCGGGGACCGGTGAGCTCCCTGGGGGAGCTCTGCTGGATCCACCGGGCCGGACTGCCGCCCGTGCCG
GCCGAGGTGGTGGGATTCCGCGGCCCCCACACCCTGCTGATGCCCCTGGGCGACGCGCGGGCCATCCGGCCCGGCAGCCT
GGTGGAAGCCACGGGCCGCGGCTTCACCGTGGGCGTGGGCGAGGGCCTGCTGGGCCGCGTCCTGGACGGCCTGGGCCGGC
CGCTGGACGGGCAGGGACCGGTGGCCGTGGAGGCGTGGTACCCCGCCGAAGGCGAGCCGCCGCCGCCGCTGGCCCGCCAG
CCGATCCGCGAGCCCCTGCCCGTGGGCGTGCGGTCCATCGACGCCCTGCTGACCTGCGGCCGGGGCCAGCGGGTCGGCAT
CTTCGCCGGCAGCGGGGTGGGCAAGAGCACGCTCCTGGCCATGATGACCCGCCACACCGCCGCCGACGTGGTGGTGGTGG
CCCTGATCGGCGAGCGGAACCGCGAAGTCCGCGACTTCGTGGACCACCACCTGGCGGGCAGCCGTCGCCGCACGGTGGTG
GTGGCGGCCACCGCCGACCGGCCCGCCCTGGTGCGGATCAAGGCCGCCCAGGTGGCCACGGCCATCGCCGAGTTCTTCCG
CGACCGGGGCCGCCACGTGCTGCTGGTGATGGACTCCGTCACCCGCTACGCCATGGCCCTGCGGGAGGTGGGGCTGGCCG
TGGGCGAGCCGCCGGCCACCCGGGGCTACCCGCCGTCGGTCTTTGCGGCCCTGCCGCGGCTGCTGGAGCGGGCCGGGACC
GGCCCCCGGGGCAGCATCACCGGGTTCTACACCGTGCTGGTGGACGGCGACGACTTGAACGAGCCCATCGCCGACGCGGT
GCGGGGCACTCTGGACGGGCACATCGTCCTGTCGCGGCAACTGGCCGAGGAAGGGCAGTTCCCCGCGGTGGACGTCCTGG
CCAGCGTCAGCCGGCTGATGCCCGAGCTGGTGGAACCGGCCCACTGGGCGGCCGCCCAGCGGTTGCGGCGGTGGCTGGGG
GCGTACCGGGAGGCCCGGGATCTGCTGGAGATCGGCGCCTACCAGCGAGGCAGCAACCCGGACGTGGACCGGGCCCTGGA
GCGGATGCCGGCCATTCGCGCCTTCCTGACCCAAGGCCGCGACGAGGCGTCGCCCTTCGCCGAGGCCGTGGCCCGGTTGC
AGGAGGTGGCCGGCGGTGCGGTGACCTAG

Protein sequence :
MAVTAADLQAAAPRMDEALPDGPDSLLDWSRLQAALETADPRPTQGWVEQVVGLAVEARGPVSSLGELCWIHRAGLPPVP
AEVVGFRGPHTLLMPLGDARAIRPGSLVEATGRGFTVGVGEGLLGRVLDGLGRPLDGQGPVAVEAWYPAEGEPPPPLARQ
PIREPLPVGVRSIDALLTCGRGQRVGIFAGSGVGKSTLLAMMTRHTAADVVVVALIGERNREVRDFVDHHLAGSRRRTVV
VAATADRPALVRIKAAQVATAIAEFFRDRGRHVLLVMDSVTRYAMALREVGLAVGEPPATRGYPPSVFAALPRLLERAGT
GPRGSITGFYTVLVDGDDLNEPIADAVRGTLDGHIVLSRQLAEEGQFPAVDVLASVSRLMPELVEPAHWAAAQRLRRWLG
AYREARDLLEIGAYQRGSNPDVDRALERMPAIRAFLTQGRDEASPFAEAVARLQEVAGGAVT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-93 53
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-91 53
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-91 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-91 53
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 6e-90 53
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-84 52
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-84 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-84 52
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-84 52
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-85 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-90 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 8e-91 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-90 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-90 51
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-87 51
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-87 51
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-68 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-72 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 9e-73 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-73 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-70 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 7e-70 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-71 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-77 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-67 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-67 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-71 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-76 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-69 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-77 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-71 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-71 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-71 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 7e-99 54
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 3e-95 54
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 2e-94 53
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 1e-84 52
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 2e-95 49
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 2e-85 49
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 3e-83 49
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 1e-93 47
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 4e-77 44
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG1008 Protein 6e-72 42
Tmar_0981 YP_004101821.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 1e-71 41