Gene Information

Name : Intca_3283 (Intca_3283)
Accession : YP_004100493.1
Strain : Intrasporangium calvum DSM 43043
Genome accession: NC_014830
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3624102 - 3626663 bp
Length : 2562 bp
Strand : -
Note : COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR018368: IPR001270: IPR017730: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: xce:Xcel_3161 ATP-dependent chaperone ClpB; PFAM: ATPase AAA; ATPase AAA; Clp domain p

DNA sequence :
ATGGATCTTCAGCTGACCACCAGGGCCCAGGAGGCCTTCGCCCAGGCGGCGACGACTGCGGCCGCCAAGCACCACCCGAA
CATCGAGCCGGCCCACCTGCTCCTCGCCCTCGCGGCCCAGCCCGGCACGACGACTCCGACCCTGCTCGAGAAGGCAGGGT
CCTCCGTCGCTGCCGCCACGGCAGCCGCGGAGAAGGAGCTGGCGGCCCTCCCGCAGGTCACCGGCGGCGCCCAGCAGCCG
CAGCTGTCGCGCACGGCCGCGGCCGCGATCCAGCAGGCCCAGCAGTACATGACGGCGATGGGGGACACGTTCGTCTCCAC
CGACCACCTCCTGCTCGCGCTGGCCCGCACCGGCCAGTTCGGCCTCGACGCCGACGCGATCGAGCAGGCCATCCCCGAGC
TGCGCGGCGGCCGCCCCGTGACGTCCGAGAACCCCGAGGGGACCTACGAGGCGCTCGCCAAGTACGGCACGGACCTCACC
GCCCGCGCTCGCGAGGGCAGGCTCGACCCGGTCATCGGTCGCGACGCCGAGATCCGCCGCGTCGTGCAGGTCCTCTCCCG
CCGCACCAAGAACAACCCGGTCCTCATCGGTGAGCCGGGCGTCGGCAAGACCGCCGTGGTCGAGGGGCTGGCGCAGCGCA
TCGTCGAGGGCGACGTGCCCGAGAGCCTGCGCGACAAGACGCTCTACTCCCTCGACCTGGCCGCCATGGTCGCCGGCGCG
AAGTACCGCGGCGAGTTCGAGGAGCGGCTCAAGGCCGTGCTCGAGGAGATCAAGGCCTCCGACGGCCAGATCGTCACGTT
CATCGACGAGCTGCACACCGTCGTCGGAGCGGGTGCCGGCAGCGAAGGCGCGATGGACGCCGGCAACATGCTCAAGCCGA
TGCTCGCCCGTGGCGAGCTGCGCCTGGTCGGCGCGACGACGCTCGACGAGTACCGCAAGCACATCGAGAAGGACGCTGCG
CTCGAGCGACGCTTCCAGCAGGTTTTCGTCGGCGAGCCCTCCGTCGAGGACACGGTCGCCATCCTGCGCGGGCTGAAGGA
GCGCTACGAGGCGCACCACAAGGTGACCATCGCCGACTCGGCGCTCGTGGCCGCGGCCAGTCTGTCCGACCGCTTCATCA
GCGGGCGCAAGCTGCCCGACAAGGCCATCGACCTCATCGACGAGGCGGCGTCGCGGCTCCGGATGGAGATCGACAGCTCA
CCGGTCGAGATCGACGAGCTGCGACGCACCGTCGACCGGCTCAAGATGGAGGAGTTCGCGCTCGAGCAGGAGCACGACGA
GGCCTCCCGCGAGCGGCTCGAGCGGCTGCGCAAGGACCTCGCCGACCGGACCGAGGAGCTCGCTGCGCTGACCGCCCGCT
GGGAGGCGGAGAAGTCCGGCCTCAACGCCGTCGGTGAGCTCAAGGCCCGGGTCGACGACCTGCGCACCCAGGCCGACCGG
CTCCAGCGGGAGGGCGACCTCGCCGGCGCCTCGAAGATCCTCTACGGCGACATCCCCACGCTCGAGAAGGAGCTCGCCGC
CGCCCAGGAGCGCGAGGCGGCCACCGTCGTCGGGAGCGAGGCCCCGATGGTCAAGGAGGAGGTCGGCGCCGACGACATCG
CCGACGTCATCTCGGCCTGGACCGGCATCCCGTCCGGCCGGCTCCTCGAGGGCGAGACCGAGAAGCTGCTCCACATGGAG
CAGCACATCGGGGCCCGCCTGATCGGCCAGACGGAGGCAGTGCGCGCCGTCTCCGACGCGGTCCGGCGCACCCGGGCCGG
CGTGTCCGACCCCGACCGGCCGACCGGCTCGTTCCTCTTCCTCGGGCCCACCGGCGTGGGCAAGACCGAGCTCGCCAAGA
GCCTCGCTGACTTCCTCTTCGACGACGAGCGGGCCATGGTCCGCATCGACATGTCCGAGTACTCGGAGCGGCACGCCGTG
GCCCGGCTCATCGGGGCGCCCCCCGGATACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGGCGGTCCGGCGCCGGCC
CTACTCCGTCATCCTGCTCGACGAGGTGGAGAAGGCGCACCCGGAGACCTTTGACGTCCTCCTTCAGGTGCTCGACGACG
GCCGCCTCACCGACGGCCAGGGGCGGACCGTGGACTTCCGCAACGTCATCCTGGTCATGACGTCGAATCTCGGGTCGCAG
TTCCTGGTGGACCCGCTGCTGTCGCCGGAGGAGAAGCGCAACGAGGTGATGGCCGTGGTCCGGGCCGCCTTCAAGCCGGA
GTTCCTCAACCGGCTCGACGAGGTCGTCGTCTTCGACGCGCTGTCCCAGCAGGAGCTGGCCGAGATCGTCGACCTGCAGG
TCCGATCGTTCGCGACCCGGCTCGCGGACCGGCGCATCACGCTGGAGGTCACGGACGCGGCGCGCACCTGGCTGGCGCAG
CGCGGTTTCGACCCGGCCTACGGCGCGCGCCCGCTGCGGCGGCTCGTCCAGAAGGAGATCGGCGACCGCCTCGCTCGGGC
CCTGCTCAGCGGCGAGGTCCGCGACGGGCAGACCGTCCGGGTCGACCGCGACACCTCCGGGGACACGCTCGTCGTCGGCT
GA

Protein sequence :
MDLQLTTRAQEAFAQAATTAAAKHHPNIEPAHLLLALAAQPGTTTPTLLEKAGSSVAAATAAAEKELAALPQVTGGAQQP
QLSRTAAAAIQQAQQYMTAMGDTFVSTDHLLLALARTGQFGLDADAIEQAIPELRGGRPVTSENPEGTYEALAKYGTDLT
ARAREGRLDPVIGRDAEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVEGDVPESLRDKTLYSLDLAAMVAGA
KYRGEFEERLKAVLEEIKASDGQIVTFIDELHTVVGAGAGSEGAMDAGNMLKPMLARGELRLVGATTLDEYRKHIEKDAA
LERRFQQVFVGEPSVEDTVAILRGLKERYEAHHKVTIADSALVAAASLSDRFISGRKLPDKAIDLIDEAASRLRMEIDSS
PVEIDELRRTVDRLKMEEFALEQEHDEASRERLERLRKDLADRTEELAALTARWEAEKSGLNAVGELKARVDDLRTQADR
LQREGDLAGASKILYGDIPTLEKELAAAQEREAATVVGSEAPMVKEEVGADDIADVISAWTGIPSGRLLEGETEKLLHME
QHIGARLIGQTEAVRAVSDAVRRTRAGVSDPDRPTGSFLFLGPTGVGKTELAKSLADFLFDDERAMVRIDMSEYSERHAV
ARLIGAPPGYVGYEEGGQLTEAVRRRPYSVILLDEVEKAHPETFDVLLQVLDDGRLTDGQGRTVDFRNVILVMTSNLGSQ
FLVDPLLSPEEKRNEVMAVVRAAFKPEFLNRLDEVVVFDALSQQELAEIVDLQVRSFATRLADRRITLEVTDAARTWLAQ
RGFDPAYGARPLRRLVQKEIGDRLARALLSGEVRDGQTVRVDRDTSGDTLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-106 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-102 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-102 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Intca_3283 YP_004100493.1 ATP-dependent chaperone ClpB VFG2084 Protein 2e-110 43
Intca_3283 YP_004100493.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-114 41