Gene Information

Name : Intca_0294 (Intca_0294)
Accession : YP_004097576.1
Strain : Intrasporangium calvum DSM 43043
Genome accession: NC_014830
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 316439 - 317962 bp
Length : 1524 bp
Strand : +
Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: nca:Noca_2092 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase (NAD(+)); PFAM: aldehyde dehydrogenase family

DNA sequence :
ATGACCATCTACGCCCCGCCCGGATCGGCGGACTCGCTCGTCAGCGTGGAGCCGCGCTACGGCCACTTCATCGGCGGCAA
CTGGGTCGAGCCGAAGAAGGGCGAGTACTTCGAGAACATCTCCCCGGTCACCGGGCGCGCCTTCTGCGAGGTGGGCCGCG
GGACGGAGGAGGACATCGAGGCGGCCCTGGACGCCGCCCACGCCGCGGCACCGGCGTGGGGACGCACCTCGCTCGGCGAC
CGCTCACTCATCCTCAACCGCATCGCCGACCGGATCGAGGAGAACCTCGAGATGCTCGCCGTGGCGGAGACGTGGGAGAA
CGGCAAGGCCGTCCGAGAGACGCTCGCCGCGGACCTGCCCCTGGCCGTCGACCACTTCCGCTACTTCGCGGGTGTGCTTC
GGGGACAGGAGGGTTCGAGCTCGGAGATCGACGAGAACACCGTCGCCTACCACTTCCACGAGCCGCTCGGGGTCGTCGGC
CAGATCATCCCCTGGAACTTCCCGATCCTCATGGCCGTGTGGAAGCTCGCGCCCGCGCTCGCGGCTGGCAACTGCGTCGT
CCTCAAGCCGGCCGAGCAGACCCCGTGGTCGATCCTCAAGGTCGTCGAGCTCATCGGCGACCTCCTCCCGGCAGGCGTCC
TCAACGTCGTCAACGGGTTCGGCGTCGAGGCCGGCAAGCCGCTCGCATCCTCCCCGCGGATCGCCAAGATCGCCTTCACG
GGCGAGACGACGACCGGCCGGCTGATCATGCAGTACGCCTCGCAGAACATCATCCCGGTGACGCTCGAGCTGGGCGGCAA
GAGTCCCAACGTCTTCTTCGACGATGTGGCGCAGGAGCGGGACGCGTTCTATGACAAGGCCCTCGAGGGTTTCACCATGT
TCGCGCTCAACCAGGGCGAGGTGTGCACCTGTCCGTCGCGCGCGCTCGTCCAGCGCTCGATCTACGCCGACTTCGTGCCG
GACGCGATCGCCCGCGTTGAGAAGATCGTCCAGGGCAACCCGCTCGACACGACGACGACGATGGGTGCACAGGCGAGCAA
CGACCAGCTCGAGAAGATCCTGTCCTACATCGACATCGGCCGGCAGGAGGGGGCCAAGGTCCTCACCGGTGGGGAGCGCA
ACGTCCTCGACGGCGACCTCGCCGGGGGCTACTACGTGACGCCGACCGTCTTCGAGGGAAGCAACTCGATGCGGATCTTC
CAGGAGGAGATCTTCGGCCCGGTCCTCTCGCTGACCGGCTTCGACGATGAGGCCGACGCGCTGTCGATCGCCAACGACAC
CCTCTACGGCCTCGGCGCCGGGGTCTGGACGCGCGACGGCTCGCGGGCGTACCGGATGGGTCGTGGCATCAAGGCCGGAC
GGGTGTGGACGAATTGCTACCACCAGTACCCTGCGCACGCAGCCTTCGGTGGCTACAAGCAGTCGGGCATCGGCCGCGAG
AACCACAAGATGATGCTCGACCACTACCAGCAGACGAAGAACCTTCTCGTCTCCTACTCTCCTGACGCCCTCGGCTTCTT
CTGA

Protein sequence :
MTIYAPPGSADSLVSVEPRYGHFIGGNWVEPKKGEYFENISPVTGRAFCEVGRGTEEDIEAALDAAHAAAPAWGRTSLGD
RSLILNRIADRIEENLEMLAVAETWENGKAVRETLAADLPLAVDHFRYFAGVLRGQEGSSSEIDENTVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNCVVLKPAEQTPWSILKVVELIGDLLPAGVLNVVNGFGVEAGKPLASSPRIAKIAFT
GETTTGRLIMQYASQNIIPVTLELGGKSPNVFFDDVAQERDAFYDKALEGFTMFALNQGEVCTCPSRALVQRSIYADFVP
DAIARVEKIVQGNPLDTTTTMGAQASNDQLEKILSYIDIGRQEGAKVLTGGERNVLDGDLAGGYYVTPTVFEGSNSMRIF
QEEIFGPVLSLTGFDDEADALSIANDTLYGLGAGVWTRDGSRAYRMGRGIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRE
NHKMMLDHYQQTKNLLVSYSPDALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-145 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 8e-151 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 8e-151 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 8e-151 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-150 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Intca_0294 YP_004097576.1 aldehyde dehydrogenase VFG0082 Protein 3e-145 63