Gene Information

Name : Intca_2644 (Intca_2644)
Accession : YP_004099876.1
Strain : Intrasporangium calvum DSM 43043
Genome accession: NC_014830
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2961479 - 2962804 bp
Length : 1326 bp
Strand : -
Note : COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: bbr:BB0876 polysaccharide biosynthesis protein; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dim

DNA sequence :
ATGCGGAACCAGGGGTTTGGAGCTCCATCTGACGTGGTGCCGCCGGCCGCGGTGCGAGACGGCACGCGGCTGGCTGTCCT
CGGCCTGGGCTATGTCGGGCTGCCGCTGGCGGTCGAGTTCGGCAAACAGTTCGACGTGCTCGGCTACGACATCGACTCGC
GGAGGGTCAAGGAGCTGCAGGACGGGCACGACCACACCTTGGAGGTCGACGACTCGGACCTCGCGGGCGCGAGCCGGCTG
CGGTTCAGCGACGACGAGGGCGACCTTGCCTGGGCCAACGTCTACATCGTCACGACGCCGACGCCCATCGATGCGCACAA
GCAGCCCGACCTGTCGCCGGTGTTGTCGGCGACCGAGGCGATCGCCCGAGCCCTCCGTCCGGGTGACGTGGTCATCTACG
AGTCGACGGTCTATCCGGGGGCCACCGAGGAGCAGTGTGTGCCCGTGCTCGAGGCCGTCTCCGGGCTGGTCTTCAACCAG
GACTTCTCCGTCGGCTACAGCCCGGAGCGGATCAACCCGGGCGACCGGGAGCACCGGCTGCCGTCGATCGTCAAGGTGAC
CTCCGGCTCGACGCCCGAGGCGGCCGACTTCGTCGACGACCTCTACCGGTCGATCATCACCGCTGGCACGCACCGGGCGC
CGTCGATCCGGGTCGCCGAGGCGGCGAAGGTCATCGAGAACACGCAGCGCGACGTCAACATCGCGCTCATCAACGAGCTC
GCGGTGCTCTTCAACCGGCTCGGCATCGACACCGAGGACGTGCTCCTCGCGGCCGGCTCGAAGTGGAACTTCCTCGGCTT
CCGACCCGGTCTCGTCGGTGGCCACTGCATCGGCGTGGACCCGTACTACCTGACCCACAAGGCACAGTCCGTCGGCTACC
ACCCCGAGGTGATCCTCGCCGGCCGCCGGCTCAACGACTCGATGGGCTCCTACGTCGCCAGCCAGCTCGTCAAGCGGATG
ACGAAGGAGGAGATCCAGGTCCACGGGGCCCGGGTCCTCGTCCTCGGTCTGACCTTCAAGGAGAACACGCCCGACCTGCG
CAACTCCCGGGTCGTGGACATCCTCGCCGAGCTCGCCGACTACGACATCACGGTGGACGTCTGCGACCCGTGGGCGGACC
CGGAGGAGGCCCGGCGGGAGTACGGAGTCGACCTCGTCGCATCCCCCGCACGCGGGGCCTATGACGGCATCATCATTGCT
GTGGCACACCACCAGTTCGTGGATCTCGGTGCCGACGGGATCCGAGCCTTCGGCAGCGCCGACGGCCACGTGGTCTATGA
CCTGAAGTATGTGCTCGGCCGAGCGGATTCGGACCTGCGGCTGTGA

Protein sequence :
MRNQGFGAPSDVVPPAAVRDGTRLAVLGLGYVGLPLAVEFGKQFDVLGYDIDSRRVKELQDGHDHTLEVDDSDLAGASRL
RFSDDEGDLAWANVYIVTTPTPIDAHKQPDLSPVLSATEAIARALRPGDVVIYESTVYPGATEEQCVPVLEAVSGLVFNQ
DFSVGYSPERINPGDREHRLPSIVKVTSGSTPEAADFVDDLYRSIITAGTHRAPSIRVAEAAKVIENTQRDVNIALINEL
AVLFNRLGIDTEDVLLAAGSKWNFLGFRPGLVGGHCIGVDPYYLTHKAQSVGYHPEVILAGRRLNDSMGSYVASQLVKRM
TKEEIQVHGARVLVLGLTFKENTPDLRNSRVVDILAELADYDITVDVCDPWADPEEARREYGVDLVASPARGAYDGIIIA
VAHHQFVDLGADGIRAFGSADGHVVYDLKYVLGRADSDLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-131 61
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-131 61
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 7e-110 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Intca_2644 YP_004099876.1 nucleotide sugar dehydrogenase VFG0431 Protein 1e-131 61