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Name : Intca_2184 (Intca_2184) Accession : YP_004099420.1 Strain : Intrasporangium calvum DSM 43043 Genome accession: NC_014830 Putative virulence/resistance : Resistance Product : dihydrofolate reductase Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0262 EC number : 1.5.1.3 Position : 2440539 - 2441003 bp Length : 465 bp Strand : - Note : COGs: COG0262 dihydrofolate reductase; InterPro IPR001796: IPR012259; KEGG: kfl:Kfla_5968 dihydrofolate reductase; PFAM: dihydrofolate reductase region; PRIAM: dihydrofolate reductase; SPTR: Probable dihydrofolate reductase oxidoreductase protein; PFAM: d DNA sequence : ATGACGAACGTGACGATGATCGCCGCCGTGGGTCGTAACGGCGTGATCGGCGACGGGTCAACAATGCTCTGGCACATCCC CGAGGACCTCAAGTTCTTCAAGCGCACGACGATGGGCCATCCGATGATCATGGGCCGGCGCACGTTCGAGACGATGGGCG TGCTCCCCGGTCGTCGCAGCATCGTCGTGACCCGCCAGCCCGACTGGGCCCACCCCGGGGTCGAGACCGCCCATTCGCTC GCCGAGGCCCTCAGCCTCGCCGGGCCGGCGGACGAGGTGTTCATCGTGGGCGGGGGAGAGGTCTATCGGGAGGCGATGCC GTATGCCGCTCGGCTCGTCATCACCGAAGTGGACCAGGCACCGGACGGCTCGGTCACCTTCCCTGAGATCGACGGCGAGC AGTGGCAGGAGACCGACCGGGAGGATCGCGACGGCTTCTCGTGGGTGACCTACGCCCGGCGCTGA Protein sequence : MTNVTMIAAVGRNGVIGDGSTMLWHIPEDLKFFKRTTMGHPMIMGRRTFETMGVLPGRRSIVVTRQPDWAHPGVETAHSL AEALSLAGPADEVFIVGGGEVYREAMPYAARLVITEVDQAPDGSVTFPEIDGEQWQETDREDRDGFSWVTYARR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| dfrA5 | AFG30110.1 | dihydrofolate reductase | Not tested | PAGI-2 | Protein | 5e-17 | 42 |
| dfrA5 | AET25387.1 | dihydrofolate reductase | Not tested | PAGI-2(C) | Protein | 5e-17 | 42 |
| dfrA1 | ADZ05803.1 | trimethoprim-insensitive dihydrofolate reductase | Not tested | AbaR3 | Protein | 4e-18 | 42 |
| unnamed | AEL12695.1 | DfrA5 | Not tested | AbaR21 | Protein | 4e-18 | 42 |
