Gene Information

Name : Intca_2081 (Intca_2081)
Accession : YP_004099318.1
Strain : Intrasporangium calvum DSM 43043
Genome accession: NC_014830
Putative virulence/resistance : Resistance
Product : arsenic resistance protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0798
EC number : -
Position : 2329590 - 2330720 bp
Length : 1131 bp
Strand : +
Note : COGs: COG0798 Arsenite efflux pump ACR3 and related permease; InterPro IPR002657: IPR004706; KEGG: nfa:pnf2250 arsenic resistance transporter; PFAM: sodium symporter; SPTR: arsenic resistance transporter; TIGRFAM: arsenic resistance protein; PFAM: Sodium

DNA sequence :
ATGAGCCAGCACGCCGACGTGACCCAGCCCAGCGGCATACGGCCCAATGGTCCCGCGACCGACCATGTGACCGAGCGCCT
GTCGACGCTCGACCGGTTCCTCCCGGTCTGGATCGGCGCCGCCATGGTGGCTGGGCTGCTCCTCGGTCGGGTCGTGCCGG
GACTGGGCGAGGCCCTGGGAGCCGTCGAGATCGACGGGGTCTCCCTGCCGATCGCGCTCGGCCTGCTCGTGATGATGTAC
CCCGTGCTGGCCAAGGTCCGCTACGACCGGCTCGACACCGTCACGGCAGACAAGCGGATGCTTGTCAGCTCGCTCGTGCT
CAACTGGCTCATCGGCCCGGCGCTGATGTTCGCCCTCGCGTGGATCTTCCTGCCCGACCTGCCCGCCTACCGCACCGGGC
TGATCATCGTCGGCCTCGCGCGCTGCATCGCCATGGTCATCATCTGGAACGACCTGGCCTGCGGCGACCGAGAGGCCGCT
GCCGTCCTCGTCGCGCTCAACTCCATCTTCCAGGTCATCGCGTTCGGCGGTCTCGGGTGGTTCTACCTGTCGGTCCTGCC
CGGCTGGCTCGGACTCGAGCAGGCGACGCTCGACGTCTCCGCGTGGCAGATCGCGAAGTCGGTGCTCATCTTCCTCGGCA
TCCCCCTCCTCGCCGGCTACCTCTCACGGACCTACGGCGAGAGGGCTCGCGGACGCGACTGGTACGAAAGGCGATTCCTT
CCCCGGATCGGCCCCTGGGCCCTCTACGGACTGCTCTTCACCATCGTCATCCTCTTCGCCCTTCAGGGTGACCAGATCTC
CAGCCGTCCCTTGGACGTGGCCCGCATCGCGGTTCCCCTGCTGGTCTACTTCGCCCTCATGTGGGGCGGCGGCTACGCGT
TGGGCAGGGCCCTCGGGATGACGTACGAGCGCACCACGACCCTCGCGTTCACCGCCGCCGGCAACAACTTCGAGCTCGCC
ATCGCGGTCGCCATCGCGACCTTCGGCATCACCTCCGGTCAGGCCCTCGCCGGGGTCGTCGGCCCCCTCATCGAGGTACC
CGTCCTGGTCGGCCTCGTCTACGTCAGCCTCTGGCTGCGCCGTCGCTTTCCCCATGCGCCGGCCCCCCTCGCGAGGAGCC
ATCATGGGTGA

Protein sequence :
MSQHADVTQPSGIRPNGPATDHVTERLSTLDRFLPVWIGAAMVAGLLLGRVVPGLGEALGAVEIDGVSLPIALGLLVMMY
PVLAKVRYDRLDTVTADKRMLVSSLVLNWLIGPALMFALAWIFLPDLPAYRTGLIIVGLARCIAMVIIWNDLACGDREAA
AVLVALNSIFQVIAFGGLGWFYLSVLPGWLGLEQATLDVSAWQIAKSVLIFLGIPLLAGYLSRTYGERARGRDWYERRFL
PRIGPWALYGLLFTIVILFALQGDQISSRPLDVARIAVPLLVYFALMWGGGYALGRALGMTYERTTTLAFTAAGNNFELA
IAVAIATFGITSGQALAGVVGPLIEVPVLVGLVYVSLWLRRRFPHAPAPLARSHHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB ADZ05767.1 arsenic resistance protein Not tested AbaR11 Protein 7e-70 54
arsB AFC76433.1 ArsB Not tested AbaR5 Protein 3e-82 53
arsB CAJ77016.1 transmembrane protein of arsenate pump Not tested AbaR1 Protein 2e-82 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Intca_2081 YP_004099318.1 arsenic resistance protein BAC0573 Protein 2e-85 53
Intca_2081 YP_004099318.1 arsenic resistance protein BAC0004 Protein 2e-63 46