Gene Information

Name : Intca_1646 (Intca_1646)
Accession : YP_004098886.1
Strain : Intrasporangium calvum DSM 43043
Genome accession: NC_014830
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1861152 - 1862609 bp
Length : 1458 bp
Strand : +
Note : COGs: COG0469 pyruvate kinase; InterPro IPR015793: IPR018209: IPR015794: IPR001697; KEGG: cfl:Cfla_1980 pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PRIAM: pyruvate kinase; SPTR: pyruvate kinase; TIGRFAM: pyruvate kinase; PFA

DNA sequence :
ATGCGTCGCGCCAAGATCGTCTGCACGATCGGTCCCAAGACATCGTCCCCCCAGCAGCTCCGAGCCCTCGTCGACGCCGG
CATGGACGTTGCCCGACTCAACCTCTCGCACGGCGAGCAGGCTCTGCACGCCCAGGTCTACCGCGACGTACGTGCCGCGA
GTGACGCCTCGGGCCGCGCGGTGGGTATCCTCGTGGACCTTCAGGGCCCGAAGATCCGGACCGGCCGCTTCAAGGACGGC
CCGGTCGAGCTCTCTCCGGGACAGCGGTTCACCATCACCACCCGCGACGTGGAGGGTGACGACACCGAGGTCAGCACGAC
CTTCAAGGGGCTGCCGCAGGACGTCCGCCCCGGCGACGTCCTGCTCATCGACGACGGCAAGGTGTGTCTGCGGGCCGTCG
ACGTCTCGGACACGGACGTCGTCACCGAGACCGTGGTCGGTGGCGAGGTGTCGAACAACAAGGGCATCAACCTGCCCGGC
GTCGCCGTGAGTGTCCCCGCTTTGTCCGAGAAGGACCGGGACGACCTGCGGTTCGCGATGCGGCTCGGCGTCGACATGGT
CGCACTTTCCTTCGTCCGCTCGGCGACCGACATCGAGGATGTCCACGCGATCATGGACGAGTTCGACCGCCGCATCCCGG
TGATCGCCAAGATCGAGAAGCCGCAGGCGGTCGCCAACCTCGAGGAGATCGTCGCCGCGTTCGACGGGATCATGGTGGCG
CGTGGAGACCTCGGCGTGGAGATGCCGCTCGAGGACGTCCCGCTCGTCCAGAAGCGCGCCTGCGAGCTCGCCCGTCAGGA
GGCCAAACCGGTCATCGTCGCGACCCAGGTGCTCGAGTCCATGATCGAGAACCCCAGGCCCACACGGGCCGAGGCATCCG
ACGCGGCCAATGCCGTGCTCGACGGAGCGGATGCGCTGATGCTGTCGGGTGAGACGTCCATCGGCGCCTGGCCGATCGAG
GCGGTCATGACCATGGCGCGCATCATCAAGTCCACCGAGGAGCACGGGCACGACAAGATCTCCCCGATGCGCACACCGAT
GACGACTGTCGCCGGGGCCATCACCAAGGCCGCCGTCGAGATCGGGGACGTCGTCGACGCGAAGTTCCTGATCACCTTCA
CCGAGACGGGAGGTTCCGCCCGACGCCAGGCGCGCCTGCGTCCGCGGCTCCCGATGCTCGCGTTCACCTCGGAGCCGCAG
ACCCGGTCCCAGCTGGCGCTCGTCTGGGGGATCGAGACCTACATCGTGCCGCGCATGATGCACACCGACCAGTTCGCGAT
GCAGGTGGACCTCAACCTCATTCCCGAGGGGCGCGTGACGGAGGGCGACCGGGTGCTCATCGTGGCCGGTTCCCCTCCCG
GCATCCCCGGGTCGACGAACGCCCTCCGCGTCCACCGGGTGGGCGATGCCGTGAACCGGGCGGCCCCCGCCTACCACCCG
GACGAGGTGACCGGCTGA

Protein sequence :
MRRAKIVCTIGPKTSSPQQLRALVDAGMDVARLNLSHGEQALHAQVYRDVRAASDASGRAVGILVDLQGPKIRTGRFKDG
PVELSPGQRFTITTRDVEGDDTEVSTTFKGLPQDVRPGDVLLIDDGKVCLRAVDVSDTDVVTETVVGGEVSNNKGINLPG
VAVSVPALSEKDRDDLRFAMRLGVDMVALSFVRSATDIEDVHAIMDEFDRRIPVIAKIEKPQAVANLEEIVAAFDGIMVA
RGDLGVEMPLEDVPLVQKRACELARQEAKPVIVATQVLESMIENPRPTRAEASDAANAVLDGADALMLSGETSIGAWPIE
AVMTMARIIKSTEEHGHDKISPMRTPMTTVAGAITKAAVEIGDVVDAKFLITFTETGGSARRQARLRPRLPMLAFTSEPQ
TRSQLALVWGIETYIVPRMMHTDQFAMQVDLNLIPEGRVTEGDRVLIVAGSPPGIPGSTNALRVHRVGDAVNRAAPAYHP
DEVTG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-66 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-66 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-65 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Intca_1646 YP_004098886.1 pyruvate kinase VFG0479 Protein 3e-66 41