Gene Information

Name : Intca_1398 (Intca_1398)
Accession : YP_004098641.1
Strain : Intrasporangium calvum DSM 43043
Genome accession: NC_014830
Putative virulence/resistance : Unknown
Product : hydroxymethylpyrimidine synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1561483 - 1563195 bp
Length : 1713 bp
Strand : -
Note : COGs: COG0422 thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: nca:Noca_3400 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; PF

DNA sequence :
ATGACGCACGCCAACCCCGCGCGGAGCAAGGTCTACGTGCCGAGCGAGCCCAGCGGCATACGGGTGCCGTTCACCGAGGT
CACCCTCACGGAAGGCAACGAACCCTTCCACCTCTACGACACATCGGGGCCCGGGAGCGTCGCCGAGGAGGGTCTCCCGC
CCGCCCGGGCTCGCTGGATCGAGGGCCGCGCCGACGTCGAGACGTACACCGGTCGGGAGCGCGACCTCGCCGACGACGGA
CGCTCGGCCGTCCGACGGGGTGAGGCGTCCCTCGAGTGGCGCGGCGAGCGGCGAGCACCGCTGCGCGCCAAGCCCGGCCG
GCGGGTCACTCAGATGGCGTACGCGCGCGCCGGCACCGTCACCCGAGAGATGGAGTACGTCGCGGCCCGCGAGCGCTGCG
ACGTCGAGCTCGTCCGATCGGAGGTCGCCGCGGGCCGGGCCATCATCCCGAGCAACGTCAACCATCCGGAGAGCGAGCCG
ATGGTCATCGGCCGGCGCTTCCTCGTCAAGATCAACGCGAACATCGGCAACTCCGCCGTGACCAGCTCGATCGCCGAGGA
GGTCGAGAAGCTCACCTGGGCGACGCGCTGGGGTGCCGACACCGTGATGGACCTGTCCACCGGCGATGACATCCACACCA
CCCGCGAGTGGATCGTGCGCAACTCGCCCGTCCCGATCGGCACCGTGCCGATCTACCAGGCGCTCGAGAAGGTGGACGGT
GACGCGTCGCAGCTCTCGTGGCCCGTCTTCCGCGACACCGTCATCGAGCAGTGCGAGCAGGGTGTCGACTACATGACCAT
CCACGCCGGGGTGCTGCTGCGCTACGTGCCGATGACGGCGCAGCGGATCACCGGCATCGTCAGCCGCGGCGGCTCGATCA
TGGCCGGCTGGTGCCTGGCCCACCACGAGGAGAACTTCCTGTACACGCACTTCGACGAGCTCTGCGAGATCTTCGCCCAG
TACGACGTCGCGTTCAGCCTCGGTGACGGGCTGCGTCCCGGCTGCACCGCGGACGCGAACGACGAGGCCCAGCTGTCCGA
GCTGCGCACCCTCGCCGAGCTGACGAAGCGGGCGTGGGAGTTCGACGTCCAGGTCATGGTCGAGGGTCCGGGCCACGTGC
CGCTCAACCTCGTCAAGGAGAACGTCGACCTCCAGCAGGACTGGTGCCACGGAGCTCCGTTCTACACGCTCGGCCCGCTC
GTGACCGACGTCGCGCCCGGCTACGACCACATCACCTCGGCGATCGGCGCCGCGCACATCGCGTGGCACGGCACGGCGAT
GCTCTGCTACGTCACGCCCAAGGAGCACCTCGGGCTGCCCAACCGGGACGACGTCAAGACCGGCGTCATCACGTACAAGC
TGGCCGCGCACGCCGCCGACGTCGCCAAGGGGCACCCGTACGCGCGCGACTGGGACGACGCCCTGTCCAAGGCGAGGTTC
GAGTTCCGGTGGGAGGACCAGTTCAACCTGTCGCTCGACCCCGACACGGCCCGTGCCTTCCACGACGAGACCCTGCCCGC
CGAGCCGGCCAAGACGGCGCACTTCTGCTCGATGTGCGGCCCGAAGTTCTGCTCCATGCGGATCTCGCAGGACGTTCGGA
GGTATGCCGCTGAGCGCGGTCTCACGGACGAGGTGGCCGTGGGTGCCGGGCTGGCGGAGAAGAGCCGCGAGTTCGTGGAG
CTCGGCTCGTCGGTGTACGTCGAGACCCCTTGA

Protein sequence :
MTHANPARSKVYVPSEPSGIRVPFTEVTLTEGNEPFHLYDTSGPGSVAEEGLPPARARWIEGRADVETYTGRERDLADDG
RSAVRRGEASLEWRGERRAPLRAKPGRRVTQMAYARAGTVTREMEYVAARERCDVELVRSEVAAGRAIIPSNVNHPESEP
MVIGRRFLVKINANIGNSAVTSSIAEEVEKLTWATRWGADTVMDLSTGDDIHTTREWIVRNSPVPIGTVPIYQALEKVDG
DASQLSWPVFRDTVIEQCEQGVDYMTIHAGVLLRYVPMTAQRITGIVSRGGSIMAGWCLAHHEENFLYTHFDELCEIFAQ
YDVAFSLGDGLRPGCTADANDEAQLSELRTLAELTKRAWEFDVQVMVEGPGHVPLNLVKENVDLQQDWCHGAPFYTLGPL
VTDVAPGYDHITSAIGAAHIAWHGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPYARDWDDALSKARF
EFRWEDQFNLSLDPDTARAFHDETLPAEPAKTAHFCSMCGPKFCSMRISQDVRRYAAERGLTDEVAVGAGLAEKSREFVE
LGSSVYVETP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 63
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 63
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-168 60